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Surrogate Endpoints: How to Choose the Best One for Your Rare Disease Trial

XTalks

In rare disease trials, it’s not always feasible to choose clinically-relevant endpoints to measure the efficacy of a new therapeutic. Symptoms and Etiology: Caused by an overproduction of growth hormone, acromegaly primarily affects adults. Acromegaly. Prevalence: 50 to 70 people per 1 million.

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Type 1 Diabetes Vaccine: Does Diamyd Have a Winning Formula?

XTalks

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. In the trial, the vaccine was injected directly into the lymph nodes of type 1 diabetic individuals. The DIAGNODE-2 Trial.

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Quick Guide to Pediatric Plaque Psoriasis

Olympian Clinical Research

With ongoing research and clinical trials , institutions like Olympian Clinical Research are at the forefront of finding innovative treatment options. Hormonal Changes: Hormonal fluctuations, especially during puberty, can influence the severity and onset of psoriasis. What is Pediatric Plaque Psoriasis?

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Why the Potential Effects of COVID-19 Vaccines on the Menstrual Cycle Are Not Concerning

XTalks

Currently, there is no scientific evidence to suggest that the vaccines induce any hormonal changes that would lead to irregular periods. Vaccines could cause an inflammatory response as part of the overall immune response. This had led some to wonder whether period changes may be a potential side effect of the vaccines.

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What Innovative Treatments For Metastatic Breast Cancer are being developed?

Find Me Cure

There currently are drugs that do just that but now they’re in clinical trials for metastatic breast cancer as well. CDK4/6 inhibitors are used alongside hormone therapy. There are antibody drugs targetting those cells that are already FDA approved and there are antibody drugs still in trials. Rosenberg, M.D.

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Research Roundup: Healthcare Workers Highest Risk for COVID-19 and More

The Pharma Data

It is a hormone. It was based on a clinical trial of people older than 40 who were showing symptoms of cognitive decline. Koronyo-Hamaoui thinks it’s possible that a specific form of immune-modulation therapy might be able to fight Alzheimer’s by decreasing toxic proteins and harmful inflammation in the brain. Working with C.

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Lynparza and Imfinzi combination improved progression-free survival in newly diagnosed patients with advanced ovarian cancer without tumour BRCA mutations in DUO-O Phase III trial

The Pharma Data

2-5 Philipp Harter, Director, Department of Gynaecology and Gynaecologic Oncology, Evangelische Kliniken Essen-Mitte, Germany and principal investigator for the trial, said: “DUO-O showcases the power of academia and industry collaboration in advancing new treatment combinations for patients with ovarian cancer.

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