Drug Discovery World

MAY 9, 2023

Jantzen Sperry , PhD, Director of Scientific Operations at Certis Oncology looks at how the adoption of orthotopic PDX models can elevate the impact of cancer research and improve translation in oncology drug development. Fewer than 5% of oncology drugs that enter clinical trials in the US receive US FDA approval.

Development 52

Development Drugs In-Vivo Clinical Trials 52

pharmaphorum

MAY 11, 2022

The importance of antibiotics in the development of modern medicine is well-established; prior to their discovery minor infections were enough to kill and the average life expectancy was 47 years old. The spread of drug-resistant pathogens poses a serious problem to treat common infections. Why AMR is a threat.

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Bacteria Development Production Vaccination 144

Drug Discovery World

JULY 27, 2022

“Mathematical oncology abstraction provides a novel and promising way to conceptualise the effect of various cancer treatments on a patient’s tumour and the local immune environment and gives us an opportunity to rethink the immunotherapy numbers game,” said Heiko Enderling, Ph.D.,

Research 52

Research Development Drugs 52

Drug Discovery World

AUGUST 22, 2023

In September 2021, the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) announced the initiation of a pilot programme 1 to provide parallel scientific advice to pharma companies applying for marketing authorisation for generic versions of hybrid products and complex generic drug products.

Production 52

Production Bioequivalency In-Vivo In-Vitro 52

Drug Discovery World

JUNE 16, 2023

” The post ISCT 2023 key trends: redefining manufacturing appeared first on Drug Discovery World (DDW). This would help meet the growing demands of viral vectors and alleviate the currently existing bottleneck, thus enabling more patients to have access to these curative therapies.”

Manufacturing 52

Manufacturing In-Vivo Production Compliance 52

Drug Discovery World

FEBRUARY 22, 2023

Advances in new manufacturing technology accelerate Back in 2019 I wrote a paper about transforming the drug life cycle, which included what I felt were the opportunities and the challenges that were going to affect the pharmaceutical sector over the next few years.

Development 52

Development Drugs Manufacturing Contract Manufacturing 52

Drug Discovery World

FEBRUARY 9, 2023

Andrew A Radin Chief Executive Officer of Aria Pharmaceuticals, on the critical use of artificial intelligence in solving some of drug discovery’s most new and complex challenges. Scientists are already using AI to accelerate the traditional drug screening and drug discovery process.

Drugs 52

Drugs Development Big Data Scientist 52

Drug Discovery World

NOVEMBER 15, 2022

Anita Ramanathan outlines four synthetic biology approaches that are improving and accelerating drug discovery. . It has made its way into almost every aspect of drug discovery, whether it’s exploring basic biology, modelling diseases, identifying and validating targets, or performing drug screens. .

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DNA Drugs Antibody Engineer 98

pharmaphorum

MAY 27, 2021

This means establishing a sustainable process that supports scientific discovery through a data-first framework that leverages technology and emphasises the development of new skills within our teams. “The organisations that will be competitive in the drug development industry will be those that enable AI capabilities” .

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Clinical Trials Clinical Trials Trials Life Science 119

Drug Discovery World

OCTOBER 2, 2023

We need to rethink comparability models and the clinical development models that would enable a therapy to move into earlier lines of treatment. One sobering statistic presented at the conference detailed that only 20% of patients who qualified to receive a CAR-TCR obtained access to the lifesaving drug.

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Pharma Marketing Network

JUNE 10, 2020

And that reduces a time of drug discovery from 10 years to five years. Where I think they are looking at disruption more broadly and intelligently is on the clinical side, the clinical guys have figured out that there are places where they can create digital partner ecosystems to truly disrupt the way they do discovery.

Marketing 52

Marketing Clinical Trials Clinical Trials Nurses 52

Pharma Marketing Network

JUNE 10, 2020

And that reduces a time of drug discovery from 10 years to five years. Where I think they are looking at disruption more broadly and intelligently is on the clinical side, the clinical guys have figured out that there are places where they can create digital partner ecosystems to truly disrupt the way they do discovery.

Marketing 40

Marketing Clinical Trials Clinical Trials Nurses 40

The Pharma Data

MAY 15, 2021

Meaning that a natural, drug-free remedy for gout is already known. I started with the standard meds: anti-inflammatories, steroid jabs, drugs to reduce the uric acid in my blood…. But even when a drug did do some good I knew I was just managing the condition. And practitioners were getting close to 100% clear-up rates.

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Bacteria Doctors Doctor Production 52