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Grand Rounds July 28, 2023: How Can Researchers Fight Misinformation About Medicine? (Carl T. Bergstrom, PhD)

Rethinking Clinical Trials

Publishers will need to rethink how to identify who is saying things and what are their credentials to make sure the ideas in the scientific literature are coming from humans who are trustworthy. How can we prioritize where to focus the resources to address misinformation? Learn more Read Misinformation in and about science.

Medicine 130
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Grand Rounds August 12, 2022: Equitably Including Diverse Participants in Pragmatic Clinical Trials (Consuelo H. Wilkins, MD, MSCI)

Rethinking Clinical Trials

How do we adjust, repair, bring in resources to recruit and work with these populations? The Trial Innovation Network Recruitment Innovation Center aims to positively impact human health by improving participant enrollment and retention in multi-center clinical trials. Passitonstudy.org/results. New Ideas study. pctGR, @Collaboratory1.

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Amtagvi (Lifileucel) Scores Landmark Win as First FDA-Approved T-Cell Therapy for a Solid Tumor

XTalks

Addressing the high price tag, Iovance’s commercial chief Jim Ziegler said, “Payers have expressed their appreciation for the value proposition for Amtagvi.” This included promising efficacy shown in animal and human trials in advanced melanoma. However, the FDA extended its review due to its own issues of resource limitations.

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Grand Rounds April 7, 2023: A Nudge Towards Cardiovascular Health: Incorporating Insights From Behavioral Science to Improve Cardiovascular Care Delivery (Srinath Adusumalli, MD, MSHP, MBMI, FACC)

Rethinking Clinical Trials

Customizing existing tools to different systems can save significant time and resources in developing behavioral health tools. They are intended to remind, guide, or motivate a decision, and they should be transparent. Dr. Srinath Adusumalli described a nudge as something that helps make the right choice an easier choice. .

Medicine 100
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The FDA’s Technical Rejection Criteria for Study Data: Does Your eCTD Submission Comply?

Camargo

A final binding guidance published April 2017, Providing Regulatory Submissions in Electronic Format — Certain Human Pharmaceutical Product Applications and Related Submissions Using the eCTD Specifications required that electronic submissions be formatted according to eCTD submission standards and defined technical rejection criteria.

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Ways IoT Has Transformed The Pulse Of Healthcare, And Will Continue To Do So In The Future

Delveinsight

The Internet of Things is the interconnection of available medical devices, software applications and other resources to collect and exchange data to provide a reliable, efficient, and smart healthcare service to the patients. The other benefit of IoT is in understanding the drug usage on the human body. Improved Drug Usage.

Doctors 59
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AI is critical to solving new complexities in drug discovery

Drug Discovery World

Basic research and new technologies are uncovering insights every day that build on our understanding of human biology. The first is that in-roads made in decoding the complexity of human disease will make drug discovery more difficult and costly, limiting the potential to develop new life-saving therapies. This creates two scenarios.

Drugs 52