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Grand Rounds January 26, 2024: Advancing the Safe, Effective and Equitable Use of AI in Healthcare (Mark Sendak, MD, MPP; Suresh Balu, MD, MBA)

Rethinking Clinical Trials

In 2021, DIHI started a Health AI Partnership to empower healthcare professionals to use AI effectively, safely, and equitably through community-informed up-to-date standards. Through this partnership, we are trying to build those skills in low resource settings and build a community of practice.

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Grand Rounds July 15, 2022: Overview of Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Public-Private Partnership and Lessons Learned (Stacey J. Adam, PhD)

Rethinking Clinical Trials

Associate Vice President, Research Partnerships. The normal timeline for public-private partnerships is around 9 months of planning. Across all is the need for clear communication, resources, and partnerships. – How did the public-private partnership contributed to the success of ACTIV? Foundation for the NIH.

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Jolly Good/Teijin Pharma develop VR digital therapeutics for depression

pharmaphorum

Technology firm Jolly Good and Teijin Pharma have begun a partnership to develop virtual reality digital therapeutics (VR DTx) for major depressive disorder. The goal of the partnership for approval for the Japanese market from the Pharmaceuticals and Medical Devices Agency (PMDA).

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Cartherics grants licence for CTH-004 to Shunxi

Pharmaceutical Technology

CTH-004 is developed by genetically altering patient T cells for inserting a chimeric antigen receptor (CAR) to target a marker (TAG-72) on ovarian cancer cells and delete genes which are involved in T cell function suppression. In animal models of ovarian cancer, it demonstrated promising results.

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Grand Rounds August 19, 2022: Inclusion and Diversity in Clinical Trials: Actionable Steps to Drive Lasting Change (Gerald Bloomfield, MD, MPH; Michelle Kelsey, MD)

Rethinking Clinical Trials

Three key themes emerged from the Think Tank discussion: build partnerships with participants and communities; improve accessibility of clinical trials; improve representation among clinical investigators. In systematic reviews, community involvement and partnership with community-based organizations are universally cited as key to success.

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Orphan drugs and where to launch them: The keys to Europe’s forgotten territories

Pharmaceutical Technology

Due to the high price tags associated with these speciality medicines, innovators have naturally favoured big markets with high GDP such as the US and EU-5 (Germany, France, Spain, Italy, and the UK). “The The Commercial Partnerships division has been known to take innovative and unique approaches to the challenges of orphan drug launch.

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Grand Rounds September 23, 2022: Effect Of An Intensive Nurse Home Visiting Program On Adverse Birth Outcomes In A Medicaid-Eligible Population (Margaret McConnell, PhD)

Rethinking Clinical Trials

The home visit services were covered through a Medicaid waiver that allowed the Nurse Family Partnership (NFP) to serve about 4,000 people over 4 years (up to 40 visits at home). We are largely looking at state data but are thinking about federal data that we can access. pctGR, @Collaboratory1.

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