Remove tag pipeline
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Cannabinoids receptors: popular preclinical target but banned in 137 countries

Pharmaceutical Technology

In 2022, a surge in the pipeline has led to cannabinoid receptors becoming the most popular target in preclinical development. Collectively, cannabinoid receptors (CB1 and CB2) are currently the most popular targets in preclinical stage of development, with 391 drugs tagged in total.

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What is Biogen and can they repair their reputation?

World of DTC Marketing

They had a new MS drug that was the talk of the industry and an exciting pipeline. Then, against the advisory panel’s advice, Aduhelm was approved, but insiders within the industry criticized both the FDA and Biogen weren’t sold on the drug or its price tag.

Drugs 222
Insiders

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Versanis’ bimagrumab, first-in-class obesity therapy, enters Phase IIb of development

Pharmaceutical Technology

Furthermore, bimagrumab is a long-acting therapy, thus significantly reducing the number of treatment days in comparison to many currently marketed and late-stage pipeline therapies. Despite its high price tag, bimagrumab’s unique features set it apart from currently marketed therapies. was observed in the study.

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A broad range of unmet needs remains in the immuno-oncology space

Pharmaceutical Technology

IO therapies come with a hefty price tag, with ICI therapies in the US typically exceeding $100,000, while cell therapies can exceed $400,000. There is currently a rich and diverse IO pipeline that aims to address these unmet needs, with 703 IO products currently in clinical trials. Cost-related unmet needs also scored highly.

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Grand Rounds January 26, 2024: Advancing the Safe, Effective and Equitable Use of AI in Healthcare (Mark Sendak, MD, MPP; Suresh Balu, MD, MBA)

Rethinking Clinical Trials

DIHI built a modular infrastructure to support many projects via a flexible data pipeline technology infrastructure that started with one model and now includes dozens of models. The next key decision point is clinical integration. – How do you get reliable information and data for care that is received outside of Duke?

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Grand Rounds August 19, 2022: Inclusion and Diversity in Clinical Trials: Actionable Steps to Drive Lasting Change (Gerald Bloomfield, MD, MPH; Michelle Kelsey, MD)

Rethinking Clinical Trials

We have made tremendous progress with some of the programs that Michelle alluded to, programs that are developing a pipeline of researchers. This is an issue that a number of institutions have been thinking about for some time. Ask questions like here’s what we think are priorities; are we right? Learn more. pctGR, @Collaboratory1.

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J&J gets first approval for multiple myeloma bispecific Tecvayli

pharmaphorum

The category is getting increasingly crowed, with Pfizer also anticipating approval of its BCMA-targeting bispecific elranatamab in the coming months, with several more multiple myeloma bispecifics coming through the pipeline from the likes of Regeneron, AbbVie, Amgen and Roche.