XTalks

OCTOBER 19, 2023

In August, Campbell Soup acquired Rao’s sauce owner Sovos Brands for $23 per share, reflecting a total value of a staggering $2.7 Despite the premium price tag, the brand has gained a cult following thanks to its inclusion of high quality ingredients and successful word-of-mouth marketing.

Branding 59

Branding Packaging Packaging Production 59

Rethinking Clinical Trials

NOVEMBER 6, 2023

Participants who are connected by group membership or share the same intervention agent will likely have correlated outcomes, which are often quantified using the interclass correlation (ICC), which reflects the extra variation attributable to group or shared agent.

Trials 130

Trials Clinical Trials Clinical Trials Contamination 130

Pharmaceutical Technology

MAY 15, 2023

Instead, their evolution takes the form of an S-shaped curve that reflects their typical lifecycle from early emergence to accelerating adoption, before finally stabilising and reaching maturity. However, not all innovations are equal and nor do they follow a constant upward trend.

Antibody 130

Antibody DNA Development Vaccination 130

Rethinking Clinical Trials

AUGUST 3, 2023

More broadly, citations in medical journals often do not reflect the material cited. Tags #pctGR, @Collaboratory1 The post Grand Rounds July 28, 2023: How Can Researchers Fight Misinformation About Medicine? One step journals can take is checking to see if cited papers have been retracted. We need to find a way to tackle this.

Medicine 130

Medicine Research Vaccination Vaccine 130

Rethinking Clinical Trials

AUGUST 23, 2022

There is a national priority to increase diversity in clinical trials, from regulatory, funding agencies, industry, and others, so that the participant population reflects the U.S. Key Points. population at large, which is steadily becoming more diverse. Learn more. pctGR, @Collaboratory1.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Medicine 130

pharmaphorum

AUGUST 21, 2022

Axsome’s drug was given a breakthrough designation from the FDA, reflecting the need for new treatment options in patients at increased risk of self harm or suicide, and was also given a priority review. However, it has a broader label as unlike J&J’s drug it is indicated for use in previously-untreated MDD.

Drugs 95

Drugs FDA Approval Production Marketing 95

Rethinking Clinical Trials

FEBRUARY 9, 2023

Researchers considered this an epiphenomenon that likely reflects the imbalance of the COVID-19 patients in the intervention group. Because of rebalancing of physicians, there were more COVID-19 patients in the intervention group.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Development 130

pharmaphorum

APRIL 5, 2022

Kimmtrak has launched in the US with an annual price tag of around $400,000 a year, reflecting the small target population, and analysts at GlobalData think that could help drive sales above $100 million – a sizeable figure for a small company like Immunocore with no other approved drugs.

Protein 52

Protein Sales Drugs Trials 52

XTalks

DECEMBER 13, 2023

Related: Roctavian Becomes First Gene Therapy for Severe Hemophilia A to Get FDA Nod Casgevy and Lyfgenia Pricing and Warnings The price tags of both gene therapies are steep, given the complexity of developing gene therapies and as therapies meant to be one-time treatments. Vertex-CRISPR’s Casgevy has a US list price of $2.2

Gene Therapy 98

Gene Therapy FDA Approval Gene In-Vivo 98

XTalks

NOVEMBER 24, 2022

While the price tag of Hemgenix is quite steep, CSL Behring told Fierce Pharma that the cost of treating patients with moderate to severe hemophilia to healthcare systems is more than $20 million over their lifetimes.

Gene Therapy 52

Gene Therapy Gene FDA Approval Genetics 52

Rethinking Clinical Trials

AUGUST 28, 2023

In terms of administrative and regulatory lessons learned, the team reflected that the integration of PT/DC at the forefront of the patient experience is often different from many typical processes. The study has enrolled 187 patients since enrollment began in March 2023, and the study team has pulled together its initial lessons learned.

Trials 130

Trials Research Medicine Doctors 130

The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins.

Vaccination 52

Vaccination Vaccine Trials Protein 52

XTalks

SEPTEMBER 27, 2022

The record-breaking price tag of Skysona is not surprising for one-time gene therapies like it. The price tag reflects “the clinical benefit [it] provides as an urgently needed treatment option to slow the progression of neurologic dysfunction in children impacted by progressive, irreversible and fatal rare disease,” Obenshain added.

FDA Approval 52

FDA Approval Gene Therapy Drugs Gene 52

Drug Discovery World

MAY 22, 2023

But are these price tags a barrier to access? For the first gene therapies, prices are high but these reflect costs and are in line with the benefits – and when the three most common haemophilia B treatments have a lifetime cost of upwards of $20 million per patient, it’s easy to see this price/benefit relationship. million per dose.

Gene Therapy 52

Gene Therapy Gene Drugs Contamination 52

pharmaphorum

JUNE 8, 2021

” He went on: “Consistent with our pricing principles, we have established a price for Aduhelm that reflects the overall value this treatment brings to patients, caregivers and society – and one that will enable continuous innovation.”

Drugs 98

Drugs Marketing FDA Approval Trials 98

The Pharma Data

MAY 4, 2021

Billion, Reflecting 42% Operational Growth; Excluding Revenues for BNT162b2 of $3.5 to $3.65, Primarily Reflecting Updates to Anticipated Contributions from BNT162b2 Partially Offset by Additional R&D Expenses for Vaccines to Protect Against COVID-19 as Well as Other mRNA-Based Development Programs and COVID-19 Antivirals.

Vaccination 40

Vaccination Vaccine Production Sales 40

pharmaphorum

AUGUST 26, 2022

BioMarin will no doubt have an eye on the earlier experience of bluebird bio, which secured EU approval for rare disease gene therapy Zynteglo (betibeglogene autotemcel) in 2019 for beta thalassaemia with a price tag of around €1.6 million spread over five years.

Gene Therapy 109

Gene Therapy Gene Antibody Marketing 109

XTalks

JANUARY 19, 2024

This biological variability adds complexity, but with that complexity comes the power to choose the targets, the tags and the payloads and select combinations appropriate to the patient to personalize that therapy. There is also potential for using several radiotherapies in combination therapies.

DNA 66

DNA Radiology FDA Approval Development 66

Cloudbyz

JUNE 1, 2023

Each dashboard can have up to 20 components and reflects the real-time data from underlying reports. This is useful for apps that require notifications to reflect changes in data as they happen to respond to business events and changes immediately. Users can also collaborate on files, add comments, and tag colleagues.

Compliance 79

Compliance Development Branding Production 79

Pharmaceutical Technology

MARCH 17, 2023

Thus, a higher risk score reflects a more hostile market access environment and drug launch in a geographical area. In some cases, she said, “[drug] innovation would have been otherwise hindered by their price tag alone”. Click here to watch this webinar and access the presentation.

Marketing 257

Marketing Drugs Research Analyst Manufacturing 257