XTalks

FEBRUARY 11, 2021

Much of the fundamental groundwork for genetics and genomic research was laid in the 20 th century, with significant contributions from women scientists, some of whom worked during times when acceptance of female researchers was not widespread. Here is a profile of some of those brilliant women who helped shape genetics research.

Genetics 119

Genetics DNA Genome Genomics 119

Roots Analysis

AUGUST 31, 2023

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Gene switches can be regulatory proteins or specific DNA sequences that act to either switch on or off the expression of a gene.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

Drug Discovery World

MAY 2, 2023

Steve Wowk , VP, Business Unit and General Management of Integrated DNA Technologies, shared with DDW the value of CRISPR-Cas9 in drug discovery. Some of the most important breakthroughs in pharmaceutical research were adapted from naturally occurring phenomena. The gRNA is accompanied by the Cas9 enzyme responsible for cutting DNA.

Genome 52

Genome Genomics Gene DNA 52

XTalks

FEBRUARY 11, 2021

The drugmaker is targeting various steps in the manufacturing process, beginning right at the DNA stage, which is required as the template from which the mRNA for the SARS-CoV-2 spike protein in the vaccine is made. DNA Templates: The vaccine development process first begins with raw ingredients coming together at the Chesterfield plant.

Manufacturing 52

Manufacturing Vaccination Vaccine DNA 52

Drug Discovery World

AUGUST 10, 2022

But decades of research led to improvements in cancer therapy, centred around the idea that one’s immune system could aid in treatment. Their continued promise has led to an exponential increase in research on their utility, function, risks, and potential benefits. Developing the first CAR T cell therapy.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

The Pharma Data

DECEMBER 2, 2020

Howard Mayer, Ipsen’s head of research and development, called the Fast Track designation for Onivyde “an extension of Ipsen’s focus and contribution” to the oncology landscape. Results show the protocol demonstrated a 30Gb+ yield of long DNA reads raw data of an E. Elsewhere around the globe: RevoluGen – U.K.-based

Drugs 52

Drugs Gene Editing Genome Genomics 52

pharmaphorum

SEPTEMBER 14, 2020

The human genome is too long to be sequenced as one continuous string by current technology – so short-read sequencing breaks DNA into short fragments that are amplified and then sequenced to produce ‘reads’ of around 150 nucleotides in length. To address these issues, scientists and clinicians are starting to look at ‘long-read’ sequencing.

Genome 116

Genome Genomics Medicine Gene 116

Drug Discovery World

MAY 4, 2023

The magic bullet was the drug, while the specific mark it would reach in the syphilis causing bacteria to eliminate the disease was the drug target. The drug target for Penicillin is a protein that helps bacteria to synthesise its cell wall. Salvarsan was soon overtaken by the Penicillin antibiotics.

Medicine 52

Medicine Protein Drugs Bioassay 52

XTalks

AUGUST 2, 2023

We delve into the driving forces behind their successes and shed light on the groundbreaking research that has earned them a place among the elite in the pharmaceutical arena. It contains the antiviral medications nirmatrelvir and ritonavir. Pfizer’s total global revenue from Paxlovid was $18.93 billion in 2022. billion in 2022.

Sales 98

Sales Manufacturing FDA Approval Life Science 98