BioSpace

DECEMBER 6, 2021

Proof of concept for the Genetically Engineered Microbial Medicines (GEMM) platform came in a recent first-in-human, Phase I trial.

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Genetic Engineering Bacteria Engineer Genetics 98

Scienmag

DECEMBER 9, 2020

A new genetic approach can accelerate the study of phage-microbe interactions with implications for health, agriculture, and climate Credit: Wikimedia Commons Scientists are continually searching for new and improved ways to deal with bacteria, be it to eliminate disease-causing strains or to modify potentially beneficial strains.

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XTalks

JULY 31, 2020

A study published in Nature on July 30, 2020 states that good bacteria living in our gut can do much more than just help digest food and boost our immune system. According to studies conducted by researchers at Cincinnati Children’s Hospital, the bacteria can help heal damaged intestinal tissues.

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Bacteria Genetic Engineering Engineer Research 98

Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. It appears to neutralise even drug-resistant bacteria. . diff, and several other deadly pathogens.

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Bacteria Engineer Gene Genetics 52

pharmaphorum

MAY 7, 2021

CRISPR’s deal with Nkarta aims to create genetically engineered NK cells, which are harvested and used to create a bank of “off the shelf” cells that can administered to patients like a drug. Nkarta also gets a license to CRISPR gene editing to an unlimited number of its own NK cell therapy products.

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The Pharma Data

JANUARY 4, 2021

But scientists at the University of California (UC), Santa Barbara, believe fluoride may offer hope in the fight against antibiotic-resistant bacteria. “Essentially, what Justin did was to create a series of DNA instructions you can give to cells that will enable them to survive when fluoride is around,” said O’Malley.

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The Pharma Data

OCTOBER 26, 2020

These mAbs are already of human origin and functionally optimized for high potency by the donor’s immune system; hence, they technically do not require genetic engineering or further optimization to achieve full functionality.

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The Pharma Data

JANUARY 19, 2021

A naturally occurring system for tuning CRISPR-Cas9 expressing in bacteria, identified in a study published in Cell , could have implications for gene editing therapies as well. In bacteria with unaltered tracr-L, levels of CRISPR-related genes were low. The authors found that tracr-L redirects Cas9 in S.

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Roots Analysis

AUGUST 31, 2023

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. However, despite several advantages, engineered T-cell therapies are prone to several adverse events, which has limited the widespread use of such effective therapeutic modalities.

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Drug Discovery World

FEBRUARY 15, 2023

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Genetically engineered mouse models (GEMM) recapitulate the stromal biology of different human cancers including the tumour microenvironment that regulates the disease process. doi:10.15252/emmm.201606857pmid:[link]

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