Scienmag

FEBRUARY 4, 2021

SSRgenotyper: A simple sequence repeat genotyping application for whole-genome resequencing and reduced representational sequencing projects. Jarvis, and P.

Genotype 90

Genotype Bioinformatics Genome Genomics 90

Medical Xpress

NOVEMBER 8, 2022

A team of researchers at Indiana University School of Medicine has developed specialized bioinformatics software designed to identify rare genetic variants in whole-genome sequencing studies. Zilin Li, Ph.D.,

Genetics 75

Genetics Bioinformatics Genome Genomics 75

pharmaphorum

SEPTEMBER 16, 2022

With approximately one third of all current FDA-approved drugs targeting GPCRs, Verily/Sosei Heptares are looking to expedite GPCR research within not only immunology, but also gastroenterology and immuno-oncology as well, and the latest data bodes well for future development of therapeutic options in these areas. What, then, is the solution?

Development 133

Development Research Drugs Clinical Trials 133

Scienmag

SEPTEMBER 7, 2020

Researchers have developed a statistical model that uses genomic data to predict the risk of developing cancer of the oesophagus Credit: Spence Phillips / EMBL-EBI Oesophageal cancer is the eighth most common cancer worldwide. It often develops from a condition called Barrett’s oesophagus.

Genome 52

Genome Genomics Development Research 52

Drug Discovery World

FEBRUARY 17, 2023

The drug discovery sector is feeling the love this Valentine’s week, with several new research collaborations bringing together a range of expertise and advanced bioinformatics, automation and artificial intelligence technologies to speed up the development of new treatments.

Bioinformatics 52

Bioinformatics Drugs Genome Genomics 52

Scienmag

JUNE 28, 2021

McIndoe, bioinformatics expert and associate director of the Center for Biotechnology and Genomic Medicine at the Medical College of Georgia, is leading a dynamic, new $6.2 Credit: Michael Holahan, Augusta University Dr. Richard A.

Bioinformatics 75

Bioinformatics Research Genome Genomics 75

Scienmag

JUNE 14, 2021

HOUSTON – (June 14, 2021) – In the two decades since the Human Genome Project mapped the entire human genome, improvements in technology have helped in developing updated reference genomes used for sequencing.

Genome 40

Genome Genomics Genome Project Gene 40

pharmaphorum

MARCH 19, 2021

The oceans of health data out there can be overwhelming for pharma companies to manage – but if extracted correctly, the prospect to develop drugs from scratch in as little as a year is very real, says Lifebit CEO, Dr Maria Chatzou Dunford. . on Big data: astronomical or genomical? , According to an article by Stephens, Zachary D.,

Bioinformatics 57

Bioinformatics Drugs Genome Genomics 57

Scienmag

JANUARY 13, 2021

To discover these associations, researchers need to compare the genomes of many individuals at millions of genetic locations or markers, and therefore require cost-effective genotyping technologies. A new statistical method, developed […].

Genome 57

Genome Genomics Genotype Genetics 57

Drug Discovery World

FEBRUARY 8, 2024

The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development. AAV is optimal for gene therapy due to its efficiency and safety in humans; however, AAV processes can present obstacles for researchers.

Gene Therapy 59

Gene Therapy Gene Bioinformatics Life Science 59

Drug Discovery World

JULY 26, 2023

An industry overview of the role of the microbiome in precision medicine, and its interplay with research tools, diagnostics, and therapeutic development. These novel tools are facilitating the exploration of the microbiome in diagnostics development and drug discovery.

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Scienmag

MAY 27, 2021

Credit: LIU Yang Researchers from the Single-Cell Center at the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences have developed a technique to sort and sequence the genome of bacteria in soil one bacterial cell at a time, while also identifying what its function is in the soil environment. […]. (..)

Bacteria 67

Bacteria Development Research Genome 67

Drug Discovery World

OCTOBER 3, 2023

The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development. AAV is optimal for gene therapy due to its efficiency and safety in humans; however, AAV processes can present obstacles for researchers.

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

Drug Discovery World

FEBRUARY 17, 2023

A new multi-year strategic partnership between M2GEN and Zephyr AI will leverage clinicogenomic data, bioinformatics, and artificial intelligence to accelerate drug discovery and expanded use cases for oncology treatments. The post Partners hope to “chart a new era of drug discovery” appeared first on Drug Discovery World (DDW).

Bioinformatics 52

Bioinformatics Drugs Licensing Licensing 52

Drug Discovery World

MAY 16, 2023

New South African company NewBiologix has launched with the aim of developing a proprietary and breakthrough platform for the advanced engineering of cell lines used to manufacture gene and cell therapies.

Production 52

Production Gene Therapy Gene Bioinformatics 52

The Pharma Data

MAY 22, 2023

WHO launches global network to detect and prevent infectious disease threats WHO and partners are launching a global network to help protect people from infectious disease threats through the power of pathogen genomics. COVID-19 highlighted the critical role pathogen genomics plays in responding to pandemic threats.

Genome 52

Genome Genomics Bioinformatics Bacteria 52

Scienmag

AUGUST 11, 2020

Researchers from Skoltech, Lomonosov Moscow State University, and the Kharkevich Institute for Information Transmission Problems have studied the genomes of some 200 strains of bacteria to determine which proteins in the ribosome, part of the key cell machinery, can be safely lost and why.

Bacteria 41

Bacteria Genome Genomics Protein 41

Drug Discovery World

NOVEMBER 30, 2023

Genomics company Broken String Biosciences has expanded its senior leadership team with the appointments of Vincent Smith as Chief Technology Officer, Jessica Rich as VP Business Development, and Gavin Burns as Vice President of Quality and Operations. Enhanc3D Genomics has appointed Hazel Jones as its new Chief Operating Officer.

Drugs 52

Drugs Genome Genomics Bioinformatics 52

Scienmag

SEPTEMBER 22, 2020

Credit: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Bottom Line: Given the toll that the COVID-19 pandemic has taken on people’s health and lives worldwide, it is crucial to be able to accurately predict patients’ outcomes, including their chances of mortality from the disease.

Development 52

Development Genome Genomics Research 52

Drug Discovery World

JULY 11, 2023

Drug discovery and development timelines can span 10-15 years or more from initial discovery to market approval and typically require the analysis of massive amounts of data. How AI and ML are influencing drug development Biopharma has experienced significant growth in using these technologies for the past 10 years.

Big Data 40

Big Data Development Life Science Drugs 40

XTalks

JULY 19, 2021

Phosphorus, a leading preventative genomics company, has developed the first comprehensive preventative genetic test for consumers. Like other consumer genomic tests, the Phosphorus GeneCompass test also involves the collection of saliva samples that consumers send to the Phosphorus lab located in Secaucus, NJ for analysis.

Genetics 98

Genetics Genome Genomics Gene 98

Drug Discovery World

APRIL 29, 2024

Hall has been with the company for more than 16 years, including as Chief Commercial Officer, and was previously Head of Business Development in Europe for Cyprotex. Bironneau brings over two decades of commercial leadership experience, including as Vice President, Global Sales & Business Development at Axplora and Novasep.

Drugs 52

Drugs Sales Gene Therapy Life Science 52

Drug Discovery World

OCTOBER 25, 2023

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development.

Bioinformatics 115

Bioinformatics Genetics RNA Drugs 115

pharmaphorum

OCTOBER 20, 2021

A software platform developed by Altoida that uses augmented reality and artificial intelligence to diagnose neurological diseases in their earliest stages is being tested in a five-year trial involving thousands of patients.

Trials 76

Trials Genome Genomics Bioinformatics 76

The Pharma Data

MARCH 20, 2021

The Kluyver Center for Genomics of Industrial Fermentation in Delft, Holland, is a consortium of several different Universities and Research Centres. Microbial genomics. The Kluyver Center applies microbial genomics to improve the performance of microorganisms in industrial fermentation processes.

Genome 52

Genome Genomics Bioinformatics Production 52

Drug Discovery World

OCTOBER 26, 2023

While we are using standard commercially available processes for genomics, we have invested massively into high-throughput and high-resolution transcriptomics, proteomics, and metabolomics methods. The technologies cover the whole range of biomolecules from genes to protein to metabolites.

Drugs 52

Drugs Protein Genome Genomics 52

Drug Discovery World

APRIL 14, 2023

At the beginning of 2023, proteomics company Nautilus Biotechnology announced a partnership with the Translational Genomics Research Institute (TGen), to study the specific proteins at work in the rare and often fatal childhood cancer, diffuse intrinsic pontine glioma (DIPG).

Protein 52

Protein Genome Genomics DNA 52

pharmaphorum

JANUARY 19, 2022

Developments in the sector have already led to significant scientific breakthroughs. All clients of Single Cell Discoveries will be able to access its platform, BBrowser, which holds single-cell multi-omics analysis developed by BioTuring. The latter was essential to be able to analyse single-cell sequencing.

RNA 70

RNA Research Life Science Bioinformatics 70

Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care. Figure 2: Advanced data visualisation examples for transcriptomics data.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

pharmaphorum

APRIL 7, 2022

During the initial stage of the collaboration, Ares developed a an AI-powered anti-infectives platform using microbiological lab techniques and bioinformatics that can be used to identify effective antimicrobial compounds or combinations against specific pathogens, which Sandoz can use to inform its “portfolio and commercial decisions.”

Bioinformatics 52

Bioinformatics Genetics Genome Genomics 52

XTalks

DECEMBER 13, 2023

In 2023, biotechnology and pharmaceutical companies leverage cutting-edge technology and significant investments in research and development (R&D) to continue pushing the boundaries of innovation in the healthcare sector, transcending the challenges posed by the pandemic.

Genetics 111

Genetics Vaccination Vaccine DNA 111

pharmaphorum

MARCH 28, 2022

Via its third call for applications, AION and BioMed X aims to entice innovative thinkers to find ways to develop solutions to common pharma challenges by analysing existing antibody therapies to make new efficient and effective therapies using AI. Then, a development stage or optimisation stage occurs. About the author .

Pharma Companies 98

Pharma Companies Antibody Protein Development 98

Drug Discovery World

APRIL 21, 2023

BMG LABTECH develops and manufactures innovative, high- quality, and reliable microplate reader instrumentation, while Microtechnix (MTX) is a company providing innovative solutions for biological laboratory assays. On the other hand, Bionomous provide AI-powered solutions for screening, sorting and dispensing of small biological entities.

Doctors 52

Doctors Doctor Genetics In-Vitro 52

The Pharma Data

SEPTEMBER 11, 2021

“Boehringer Ingelheim believes Twist’s ability to generate potent, diverse therapeutic antibodies by mining its comprehensive libraries, combined with our extensive capabilities and experience in drug discovery and development, will enable us to deliver breakthrough opportunities to patients,” said Clive R. Wood, Ph.D., Leproust, Ph.D.,

Antibody 52

Antibody DNA Containment Manufacturing 52

Drug Discovery World

JULY 29, 2022

Scientists from seven research institutions including the University of Oxford and the University of Edinburgh have used pioneering bioinformatic modelling to investigate the molecular interactions of the p53 protein known to give protection against cancers.

Gene 52

Gene DNA Protein Genetics 52

Drug Discovery World

APRIL 6, 2023

The workshop will be led by hfp consulting, a firm which specialises in career development and leadership training for scientists. These topics will be represented across a range of session types, including methods workshops, minisymposia, poster and plenary sessions, as well as keynotes, awards and lectures.

Protein 52

Protein Clinical Trials Clinical Trials Antibody 52

The Pharma Data

DECEMBER 16, 2020

Evotec and Bristol Myers Squibb (the successor in interest to Celgene ) initiated their long-term strategic drug discovery and development partnership in the field of targeted protein degradation in 2018 with the goal to identify novel drug targets.

Protein 40

Protein Containment Bioinformatics Drugs 40