XTalks

DECEMBER 13, 2023

3) Fulgent Genetics Compound annual growth rate: 260 percent Fulgent Genetics, headquartered in California, is a technology-driven company with a strong presence in clinical diagnostics and therapeutic development. The company achieved core revenues of $67 million, reflecting a remarkable 48 perecent year-over-year growth.

Genetics 111

Genetics Vaccination Vaccine DNA 111

Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Many tumours have a higher number of mutations due to a antiviral defence mechanism, the APOBEC system, which can accidentally damage DNA and cause mutations.

Scientist 53

Scientist DNA Genetics Medicine 53

Drug Discovery World

APRIL 18, 2023

would not have qualified for genetic screening under current guidelines, according to results from the Tapestry clinical trial presented at AACR 2023 today. Read more here. Read more here. This award recognises an individual on the basis of their meritorious achievements and contributions to any aspect of blood cancer research. AACR James S.

Genetics 52

Genetics DNA Research Bioinformatics 52

Scienmag

MARCH 12, 2021

UMD-led research identifies age-related changes to DNA and reveals longevity-related differences between bat species Credit: G. Tschapka A new study led by University of Maryland and UCLA researchers found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. Wilkinson, G. Puechmaille, M.

DNA 98

DNA Research Bioinformatics Genetics 98

Scienmag

MAY 27, 2021

Cellular proteins get their marching orders from genetic instructions encoded in DNA, whose sequences are first copied and made […].

Gene Expression 41

Gene Expression RNA DNA Protein 41

Scienmag

JULY 20, 2021

Credit: Field Museum The Xerces blue butterfly was last seen flapping its iridescent periwinkle wings in San Francisco in the early 1940s.

DNA 92

DNA Development Bioinformatics Genetics 92

Scienmag

APRIL 20, 2021

Real-world disease and parasite monitoring is often hampered by the inability of traditional approaches to easily sample broad geographical areas and large numbers of individuals. This can result in patchy data that fall short of what researchers need to anticipate and address outbreaks.

RNA 72

RNA DNA Research Bioinformatics 72

XTalks

SEPTEMBER 28, 2020

Based on the genetic biomarker(s) identified, the most effective therapy targeting the specific molecular marker can be selected. The test involves isolating circulating tumor DNA in the blood and sequencing it to look for relevant gene mutations.

Gene 105

Gene DNA Life Science Genotype 105

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

Genetics 52

Genetics Research Medicine Clinical Research 52

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA). Optimal methods for bioinformatic analysis are still needed. percent show less reliability).

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Drug Discovery World

JULY 11, 2023

Now, with the growth of publicly available genomics, transcriptomics, and proteomics databases, the ability to quickly carry out large-scale DNA, RNA, and protein screenings, and the availability of massive sets of de-identified patient data, the amount of high-value, analysable data has reached enormous proportions.

Big Data 40

Big Data Development Life Science Drugs 40

Drug Discovery World

OCTOBER 25, 2023

There are two main concepts underlying this impact; we’ve known for a few years now that people can have variable responses to the same medication and that these responses are largely based on an individual’s genetic makeup. NGS is becoming invaluable for treating individual cancer patients based on their tumour’s genetic makeup.

Bioinformatics 115

Bioinformatics Genetics RNA Drugs 115

Drug Discovery World

NOVEMBER 15, 2022

Rapid and accurate DNA synthesis . Conventional DNA synthesis, typically used for making sequences such as primers, employs phosphoramidite chemistry, a method that was developed in the 1980s and is still considered the gold standard for DNA synthesis. .

DNA 98

DNA Drugs Antibody Engineer 98

Drug Discovery World

JULY 26, 2023

With 100-fold the number of genes in the human genome 1 , this microbial collection is a rich genetic signature of clinical significance that we have only recently gained the tools to explore. Collectively, these systems biology bioinformatic puzzles often require partnerships to solve.

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Drug Discovery World

JULY 29, 2022

Scientists from seven research institutions including the University of Oxford and the University of Edinburgh have used pioneering bioinformatic modelling to investigate the molecular interactions of the p53 protein known to give protection against cancers.

Gene 52

Gene DNA Protein Genetics 52

pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. While it is a very rare form of epilepsy, it is such a cheap and harmless medication that it is often used as a first-line therapy for infants in intensive care who have no genetic diagnosis.

Genome 107

Genome Genomics Medicine Gene 107

Drug Discovery World

APRIL 14, 2023

Whilst the cause of DIPG isn’t known, the disease is characterised by specific mutations in genes coding for histone proteins – a family of basic proteins which can associate with DNA due to their positive charges. BMC Bioinformatics. These mutated proteins then reprogramme the epigenome, from which the cancer develops.

Protein 52

Protein Genome Genomics DNA 52

Drug Discovery World

NOVEMBER 9, 2023

Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’. Marine Houdou, Genetic Engineering Specialist, Polyplus, on: ‘From modular DNA assembly to recombinant protein production at Polyplus’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. Moving on From the Amyloid Hypothesis. “I Same with Alzheimer’s.

Vaccination 52

Vaccination Vaccine Regulation Drugs 52