Scienmag

OCTOBER 27, 2020

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

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Scienmag

JANUARY 13, 2021

Credit: Delaneau Group Thousands of genetic markers have already been robustly associated with complex human traits, such as Alzheimer’s disease, cancer, obesity, or height.

Genome 57

Genome Genomics Genotype Genetics 57

Scienmag

JANUARY 13, 2021

International Ukraine Genetic Diversity Project finds a quarter of the genetic variation in Europe, dramatically increasing information on population diversity and medical genetic variation Credit: Oakland University Today, the largest study of genetic diversity in Ukraine was published in the open science journal GigaScience.

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Scienmag

APRIL 28, 2021

In collaboration with VGP, the research group has published a research paper in Nature on platypus and echidna genomes early this year (see report in the right column).

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Scienmag

AUGUST 21, 2020

An international team of scientists used genomic analysis to compare the main cellular receptor for the virus in humans — angiotensin converting […].

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Scienmag

SEPTEMBER 7, 2020

Researchers have developed a statistical model that uses genomic data to predict the risk of developing cancer of the oesophagus Credit: Spence Phillips / EMBL-EBI Oesophageal cancer is the eighth most common cancer worldwide. It often develops from a condition called Barrett’s oesophagus.

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Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

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pharmaphorum

AUGUST 10, 2021

The three-year project – led by respiratory medicine expert Dr Timothy Hinks from the Oxford University Respiratory Medicine Unit – will use whole-genome sequencing of around 500 patients with severe asthma, comparing their gene sequences with control subjects who don’t have asthma.

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Gene Sequencing Bioinformatics Gene Genome 116

Drug Discovery World

FEBRUARY 17, 2023

A new multi-year strategic partnership between M2GEN and Zephyr AI will leverage clinicogenomic data, bioinformatics, and artificial intelligence to accelerate drug discovery and expanded use cases for oncology treatments. million lives around the world,” said Grant Verstandig, Co-Founder and Executive Chairman of Zephyr AI.

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Scienmag

SEPTEMBER 22, 2020

Credit: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Bottom Line: Given the toll that the COVID-19 pandemic has taken on people’s health and lives worldwide, it is crucial to be able to accurately predict patients’ outcomes, including their chances of mortality from the disease.

Development 52

Development Genome Genomics Research 52

XTalks

DECEMBER 13, 2023

These efforts encompass programs related to the shingles vaccine, Tdap vaccine and plague vaccine, reinforcing Dynavax’s commitment to advancing the field of vaccines and medicine. The year 2022 has proven to be a momentous period for Fulgent Genetics, marked by significant expansion of its product portfolio across various medical conditions.

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pharmaphorum

SEPTEMBER 16, 2022

Essentially, the collaboration brought together both “the right expertise and the right technology”, opening up myriad possibilities for targeting GPCRs within the human genome. Kim recognised then, he said, that better tools for medicine needed to be developed, and that they still do. What, then, is the solution?

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Scienmag

APRIL 28, 2021

April 28) – The University of Washington’s School of Medicine Brotman Baty Institute for Precision Medicine is collaborating with Illumina, Inc. Supporting families of children with developmental differences SEATTLE and GAITHERSBURG, MD. Nasdaq: ILMN) and GeneDx, Inc.,

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Genome Genomics Medicine Bioinformatics 56

Scienmag

MARCH 30, 2021

The new tool enhances the replicability of large genomic datasets UNIVERSITY PARK, Pa. For example, to evaluate the validity of a high-throughput genetic […].

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pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential.

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Genome Genomics Medicine Gene 119

Scienmag

DECEMBER 16, 2020

15, 2020 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become. Comparative analysis of human and animal coronaviruses strains implicates miR1307 PHOENIX, Ariz.

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Scienmag

MARCH 22, 2021

Using genomics, the team tracked DNA changes occurring in melanoma samples donated by patients as their disease progressed, right through to the time the patient died. […].

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DNA Genome Genomics Research 96

Scienmag

OCTOBER 15, 2020

Scientists in Cambodia have used the new IDseq tool to confirm and sequence the whole genome of the country’s first case of COVID-19 Credit: IDseq.net 15th October 2020, Hong Kong: Published today in the journal GigaScience is a new open source, cloud-based tool called IDseq that makes it possible to rapidly detect, identify, and track […]. (..)

Genome 98

Genome Genomics Scientist Bioinformatics 98

Drug Discovery World

JULY 26, 2023

An industry overview of the role of the microbiome in precision medicine, and its interplay with research tools, diagnostics, and therapeutic development. But what advancements are taking place within microbiome-based precision medicine and how is it being used within oncology?

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Drug Discovery World

APRIL 14, 2023

Carl H June, MD, FAACR – Lifetime Achievement in Cancer Research June, a Fellow of the AACR Academy, is the Richard W Vague Professor in Immunotherapy, Director of the Center for Cellular Immunotherapies, and Director of the Parker Institute for Cancer Immunotherapy in the Perelman School of Medicine at the University of Pennsylvania.

Genetics 52

Genetics Research Medicine Clinical Research 52

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. Increasingly, major collaborative life sciences projects, like the Human Genome Project or Human Cell Atlas, are driving advancements and organisations – both public and private – are taking note.

Genome 52

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XTalks

MAY 20, 2022

Depending on the type of field or company, you can pursue clinical scientist jobs with a major in biology, medicine, medical technology, chemistry, immunology and other related life science and pre-medical degrees. Genetic Science. What Field Can You Work in as a Clinical Scientist? Clinical Pharmaceutical Science. Blood transfusion.

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Drug Discovery World

JULY 11, 2023

Now, with the growth of publicly available genomics, transcriptomics, and proteomics databases, the ability to quickly carry out large-scale DNA, RNA, and protein screenings, and the availability of massive sets of de-identified patient data, the amount of high-value, analysable data has reached enormous proportions.

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Drug Discovery World

OCTOBER 25, 2023

DG : I think the most impact is being made in personalised medicine. There are two main concepts underlying this impact; we’ve known for a few years now that people can have variable responses to the same medication and that these responses are largely based on an individual’s genetic makeup. The second concept is largely in oncology.

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Bioinformatics Genetics RNA Drugs 112

XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. Dr. Bahassi explained that technological advances in genetic sequencing of cfDNA have enabled liquid biopsies and led to marked increase in the detection of therapeutically-targetable mutations. Optimal methods for bioinformatic analysis are still needed.

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Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

Big Data 52

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Drug Discovery World

APRIL 21, 2023

Managing all of these elements using iterative design and prototyping can play a key role in successful project delivery, and marrying technologies with biochemical or cellular assays has the potential to bring disruptive change across fields as diverse as personalised medicine, diagnostics and drug screening.

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Drug Discovery World

NOVEMBER 15, 2022

Gene-to-antibody production begins with scientists entering antibody sequences as starting material, after which bioinformatics tools filter out potentially non-viable sequences. Researchers used it to elucidate the genetic code and mechanism of protein synthesis back in the 1960s. This approach has been around for a while.

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DNA Drugs Antibody Engineer 98

Drug Discovery World

NOVEMBER 8, 2023

Annemie Deiteren, MD, PhD, Director, Translational Medicine & Clinical Pharmacology, Translational Medicine & Early Development, Sanofi, on: ‘Multispecific, multivalent TSLP-IL13 NANOBODY’. Chairperson Mark Chiu, on: ‘Strategies to enhance efficacy of a tetraspecific antibody to TNBC and PDAC’.

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The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. Really, a lot of the drugs that we use in clinical practice are actually preventative medicines.

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