Drug Discovery World

NOVEMBER 17, 2022

Researchers have identified 35 genes associated with long-term Lyme disease that could potentially be used as biomarkers to diagnose patients with the condition. . The researchers also identified a subset of genes that were highly expressed but have not been previously established for this Lyme-associated inflammatory response. .

Genetics 52

Genetics RNA Immune Response Bioinformatics 52

pharmaphorum

JULY 20, 2022

Cancer Research UK has expanded an alliance with investment group Deep Science Ventures with a commitment to support the formation up to 10 new oncology startups. The post Cancer Research UK partnership aims to back 10 new startups appeared first on.

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Research Bioinformatics Gene Therapy Medicine 84

Scienmag

APRIL 20, 2021

A new study challenges the presumption that all South-Eastern-Bantu speaking groups are a single genetic entity. Almost 80% of South Africans speak one of the SEB family languages as their first language.

Genetics 61

Genetics Research Bioinformatics Gene 61

Scienmag

OCTOBER 27, 2020

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

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Scienmag

FEBRUARY 25, 2021

Scott Devine, PhD 64 human genomes sequenced will serve as new reference for genetic variation and predisposition to human diseases Credit: NIH Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes.

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pharmaphorum

SEPTEMBER 16, 2022

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. It is the horizon looker, seeing far more – and, at that, far more expediently – than the human researcher alone ever could. What, then, is the solution?

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Scienmag

APRIL 30, 2021

Researchers have identified a vulnerability in some cases of acute myeloid leukaemia that could be harnessed for targeted treatment of these poor-prognosis cancers Targeting a pathway that is essential for the survival of certain types of acute myeloid leukaemia could provide a new therapy avenue for patients, the latest research has found.

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Scienmag

FEBRUARY 4, 2021

Applications in Plant Sciences… SSRgenotyper is a newly developed, free bioinformatic tool that allows researchers to digitally genotype sequenced populations using simple sequence repeats (SSRs), a task that […].

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Genotype Bioinformatics Genome Genomics 90

Scienmag

APRIL 23, 2021

This can be helpful in the study of rare genetic defects, among other things. A new VR platform enables the display of huge amounts of data. Credit: Sebastian Pirch, published in Nature Communications 2021. Networks offer a powerful way to visualize and analyze complex systems.

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Genetics Research Bioinformatics Gene 92

Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

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DNA Research Genetics Scientist 69

Scienmag

JANUARY 27, 2021

New research from the University of Illinois says yes. In a paper published in Evolutionary Bioinformatics, Illinois researchers show COVID-19 cases and mortality rates, among other […]. . – With cities around the globe locking down yet again amid soaring COVID-19 numbers, could seasonality be partially to blame?

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Scienmag

JANUARY 13, 2021

Credit: Delaneau Group Thousands of genetic markers have already been robustly associated with complex human traits, such as Alzheimer’s disease, cancer, obesity, or height.

Genome 57

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XTalks

APRIL 21, 2023

The application of whole genome sequencing (WGS) to derive a more complete understanding of cancer has been a central goal of cancer researchers even before the first human genome was decoded in 2003. WGS can also help identify the specific genetic alterations that underlie drug resistance in cancer cells.

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Drug Discovery World

NOVEMBER 7, 2022

A new study led by Medical Research Council-funded researchers from UCL has found that tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases. . Dr Pitceathly continued: “In this study, every new genetic diagnosis had a direct impact on patient care.

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Scienmag

JANUARY 13, 2021

International Ukraine Genetic Diversity Project finds a quarter of the genetic variation in Europe, dramatically increasing information on population diversity and medical genetic variation Credit: Oakland University Today, the largest study of genetic diversity in Ukraine was published in the open science journal GigaScience.

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Drug Discovery World

FEBRUARY 17, 2023

A new multi-year strategic partnership between M2GEN and Zephyr AI will leverage clinicogenomic data, bioinformatics, and artificial intelligence to accelerate drug discovery and expanded use cases for oncology treatments.

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Bioinformatics Drugs Licensing Licensing 52

Drug Discovery World

APRIL 18, 2023

DDW’s Megan Thomas rounds up highlights from Tuesday 17 April at AACR 2023, from AI and mathematical oncology to winners of the AACR James S Ewing-Thelma B Dunn Award for Outstanding Achievement in Pathology in Cancer Research. Read more here. AACR James S. Ewing-Thelma B.

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Genetics DNA Research Bioinformatics 52

pharmaphorum

JULY 5, 2022

It can be caused by exposure to loud noises – including prolonged use of earbuds at high volumes – as well as cancer treatment, illnesses, genetic mutations, or aging. An estimated 1.57

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Scienmag

AUGUST 31, 2020

Toward a single-cell atlas of human organoids for biomedical research Credit: HCA Organoid HCA|Organoid is a new EU research project that combines single-cell profiling and organoid technology to validate organoids as faithful models of human biology.

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Scienmag

MAY 19, 2021

Credit: John Innes Centre Researchers have found the elusive genetic element controlling the elongated grains and glumes of a wheat variety identified by the renowned botanist Carl Linnaeus more than 250 years ago. Wheat, in bread, pasta, […].

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Genetics Production Research Bioinformatics 79

Scienmag

JANUARY 20, 2021

Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans. Credit: Jan Zrimec/Chalmers University of Technology Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected.

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Bacteria Genetics Development Research 97

Scienmag

SEPTEMBER 22, 2020

Credit: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Bottom Line: Given the toll that the COVID-19 pandemic has taken on people’s health and lives worldwide, it is crucial to be able to accurately predict patients’ outcomes, including their chances of mortality from the disease.

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Scienmag

AUGUST 25, 2020

The chip allows researchers to genetically identify corals and the symbiotic algae that live within the coral’s cells, a vital step for establishing and maintaining genetic diversity in reef restoration efforts. […].

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Genotype Genetics Development Research 66

Scienmag

JULY 16, 2021

Credit: Vaughn Cooper PITTSBURGH, July 16, 2021 – For the first time ever, researchers from the University of Pittsburgh School of Medicine discovered that phages–tiny viruses that attack bacteria–are key to initiating rapid bacterial evolution leading to the emergence of treatment-resistant “superbugs.”

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Research Bacteria Medicine Bioinformatics 73

Scienmag

JANUARY 8, 2021

Credit: University of Leeds Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells.

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Packaging Packaging Genetics Research 94

Scienmag

MAY 27, 2021

Cellular proteins get their marching orders from genetic instructions encoded in DNA, whose sequences are first copied and made […].

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Scienmag

SEPTEMBER 28, 2020

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient’s […].

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Gene Genetics Development Research 74

XTalks

DECEMBER 13, 2023

In 2023, biotechnology and pharmaceutical companies leverage cutting-edge technology and significant investments in research and development (R&D) to continue pushing the boundaries of innovation in the healthcare sector, transcending the challenges posed by the pandemic.

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Scienmag

SEPTEMBER 4, 2020

Jonek The European Research Council (ERC) has awarded ERC Starting Grants to two researchers from Bielefeld University. million euros for top-level research in their disciplines. ERC Starting Grants for Professor Dr Martina Hofmanová and Dr Toni Goßmann Credit: Photo: Bielefeld University /S. They will each receive 1.5

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Research Bioinformatics Gene Genetics 56

Scienmag

APRIL 29, 2021

Credit: California Academy of Sciences Within the past decade, next-generation sequencing technologies have revolutionized the way in which genetic data are generated and analyzed.

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Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Researchers at IRB Barcelona led […].

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Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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Genetics Research Medicine Clinical Research 52

Scienmag

MARCH 30, 2021

— A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. For example, to evaluate the validity of a high-throughput genetic […].

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Scienmag

DECEMBER 16, 2020

15, 2020 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become. Comparative analysis of human and animal coronaviruses strains implicates miR1307 PHOENIX, Ariz.

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XTalks

MAY 20, 2022

Do you possess laboratory skills, an analytical mindset and a penchant for research? A clinical scientist conducts research to help prevent illness and develops techniques to support patient diagnosis and treatment. They will often find themselves working in a healthcare or pharmaceutical field that supports human health research.

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Scienmag

JULY 1, 2021

Almost twenty years ago, the process of RNA silencing was discovered in plants, whereby small fragments of RNA inactivate a portion of a gene during protein synthesis.

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RNA Protein Research Gene 60

XTalks

SEPTEMBER 28, 2020

Based on the genetic biomarker(s) identified, the most effective therapy targeting the specific molecular marker can be selected. Some of these are second generation therapies that can overcome known resistance mutations to earlier therapies, such as EGFR T790M or ALK L1196M or ALK G1269A.

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