Drug Discovery World

NOVEMBER 7, 2022

In 2018, the UK’s department of health announced an NHS Genomic Medicine Service, which allows patients with rare diseases to have their entire genetic code read in the hope of providing a much-needed diagnosis. That said, some people with rare genetic diseases remain without a molecular diagnosis after their genome is analysed. . “We

Genome 52

Genome Genomics Genetics Genetic Disease 52

Scienmag

FEBRUARY 4, 2021

Study has big implications for management of bat populations Credit: Sarah Gignoux-Wolfsohn Scientists have found genetic differences between bats killed by white-nose syndrome and bats that survived, suggesting that survivors rapidly evolve to resist the fungal disease, according to a Rutgers-led study with big implications for deciding how to safeguard (..)

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Gene Genetics Scientist Bioinformatics 91

Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

DNA 69

DNA Research Genetics Scientist 69

Scienmag

APRIL 27, 2021

Credit: Nigel Michki Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

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RNA Scientist Gene Development 98

pharmaphorum

JULY 20, 2022

DSV’s involvement will provide pre-seed capital for the new ventures, which will be incubated within Cancer Research Horizon’s wet labs with support from scientists among its researcher network.

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Research Bioinformatics Gene Therapy Medicine 83

Scienmag

SEPTEMBER 29, 2020

Cutting-edge nanopore devices have enabled scientists to read or ‘sequence’ the genetic material in a biological sample outside a laboratory, however analysing the raw data has […].

Genome 55

Genome Genomics Genetics Scientist 55

Scienmag

JANUARY 29, 2021

In 2017, the Nobel Prize in Physiology or Medicine went to three scientists who uncovered the molecular mechanisms that control the circadian rhythm, otherwise known as the “wake-sleep” cycle.

Gene 69

Gene Scientist Medicine Research 69

The Pharma Data

MAY 22, 2023

Pathogen genomics analyzes the genetic code of viruses, bacteria and other disease-causing organisms to understand how infectious they are, how deadly they are, and how they spread. Diseases do not respect borders: a disease threat in one country is also a threat to others.

Genome 52

Genome Genomics Bioinformatics Bacteria 52

Scienmag

OCTOBER 15, 2020

Scientists in Cambodia have used the new IDseq tool to confirm and sequence the whole genome of the country’s first case of COVID-19 Credit: IDseq.net 15th October 2020, Hong Kong: Published today in the journal GigaScience is a new open source, cloud-based tool called IDseq that makes it possible to rapidly detect, identify, and track […]. (..)

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Genome Genomics Scientist Bioinformatics 98

Scienmag

AUGUST 21, 2020

An international team of scientists used genomic analysis to compare the main cellular receptor for the virus in humans — angiotensin converting […].

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Genome Genomics Scientist Bioinformatics 91

Scienmag

OCTOBER 22, 2020

For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species. Credit: Illustration by Amy Koehler Poop is full of secrets. When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again.

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DNA Containment Scientist Bioinformatics 54

Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. Dalla-Favera’s award lecture will be held on Tuesday April 18 at 3:45pm ET.

Genetics 52

Genetics Research Medicine Clinical Research 52

Scienmag

MARCH 9, 2021

By using analytical and sequencing technology that has only been developed in recent years, scientists from Wellcome […]. Instead, selection pressures from before widespread use of antibiotics influenced some of them to develop, new research has discovered.

Bacteria 47

Bacteria Scientist Development Research 47

Drug Discovery World

JULY 19, 2023

Bioinformatics and genetic sequencing are starting to be placed front and centre of public research programmes as scientists from around the world recognise the substantial benefits of knowledge sharing and resource pooling when it comes to genetic science. What does open science look like?

Genome 52

Genome Genomics Bioinformatics Genetics 52

XTalks

APRIL 21, 2023

Biotech company Ultima Genomics has joined forces with Genome Insight, a bioinformatics-based biomedicine company, to overcome the caveat of cost and quality in WGS. Genome sequencing requires a powerful sequencer to decode the genetic makeup and an equally powerful analysis platform to make sense of the data generated.

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Genome Genomics Bioinformatics Genetics 97

Drug Discovery World

JULY 11, 2023

These tumours retain the unique genetic characteristics of patients’ tumours and are considered a gold standard for studying disease biology and predicting patient-specific tumour responses. These models are developed from tumour fragments surgically dissected from cancer patients and transplanted into immunodeficient mice.

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Big Data Development Life Science Drugs 40

Scienmag

NOVEMBER 11, 2020

New method bridges in situ microscopy with single cell omics Credit: Wheeler lab Scientists can now select individual cells from a population that grows on the surface of a laboratory dish and study their molecular contents.

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Scientist Development Research Bioinformatics 98

Drug Discovery World

JULY 29, 2022

Scientists modelling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions – with implications for cancer treatments in humans.

Gene 52

Gene DNA Protein Genetics 52

Drug Discovery World

NOVEMBER 8, 2023

Sebastian Jaeger, PhD, Senior Scientist, ADCs & Targeted NBE Therapeutics, Merck Healthcare KGaA, on: ‘Evaluation of Fcab-drug conjugates as a novel antibody-based format for targeted drug delivery’. Mireille Vankemmelbeke, PhD, Principal Scientist, Biodiscovery, Scancell, on: ‘Glycan and novel targets for bispecific cancer therapy’.

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Antibody Engineer Protein Scientist 64

Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

Drug Discovery World

NOVEMBER 9, 2023

Gail Calvert, Field Application Scientist, Sartorius UK, on: ‘Leveraging integrated and advanced technologies for successful cell line development’. Jorge Dias, PhD, Principal Scientist, Alchemab Therapeutics, on: ‘A patient-first approach to discover first-in-class antibody therapeutics’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. While it is a very rare form of epilepsy, it is such a cheap and harmless medication that it is often used as a first-line therapy for infants in intensive care who have no genetic diagnosis.

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Genome Genomics Medicine Gene 115

Drug Discovery World

APRIL 14, 2023

DDW Editor Reece Armstrong speaks to Nautilus Co-Founder and Chief Scientist Parag Mallick , about the company’s recent collaboration which aims to uncover the proteins that could be behind a rare and fatal childhood cancer. And whilst proteomics isn’t a new field of study, it has largely been left in the hands of proteomics scientists. “If

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Protein Genome Genomics DNA 52

Drug Discovery World

NOVEMBER 15, 2022

Even as methods in DNA synthesis continue to advance, scientists’ reliance on third-party companies for synthesising DNA creates a bottleneck, impeding research timelines. . “If Researchers used it to elucidate the genetic code and mechanism of protein synthesis back in the 1960s. This approach has been around for a while.

DNA 98

DNA Drugs Antibody Engineer 98

pharmaphorum

MARCH 28, 2022

AION Labs’ third call for applications seeks computational biologists, bioinformatics and cheminformatics scientists, AI researchers, and antibody or protein engineers at academic and industry research labs worldwide to assemble a fully funded start-up company. From there, they evaluate what kind of antibodies are produced.

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Pharma Companies Antibody Protein Development 98