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Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome

Scienmag

The researchers have demonstrated that silencing or inhibiting the activity of these proteins completely reverses the aortic disease in a mouse model of Marfan Syndrome Credit: CNIC Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de BiologĂ­a Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) (..)

Protein 96
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Diabetes researchers discover the potential of CIDEC protein to mitigate obesity-related cardiometabolic disease

Medical Xpress

A team of researchers from Ohio University's Heritage College of Osteopathic Medicine has recently discovered a novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health.

Protein 69
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Older women who ate more plant protein had lower risk of premature, dementia-related death

Scienmag

24, 2021 — Postmenopausal women who ate high levels of plant protein had lower risks of premature death, cardiovascular disease and dementia-related death compared with women who ate less plant proteins, according to new research published today in the Journal of the American Heart Association, an […].

Protein 64
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High fat diets may over-activate destructive heart disease protein

Scienmag

Peer Reviewed Experimental Animals Consumption of a high fat diet may be activating a response in the heart that is causing destructive growth and lead to greater risk of heart attacks, according to new research.

Protein 51
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New activity found for CHD7, a protein factor vital in embryonic development

Scienmag

Mutations in CHD7 cause severe birth defects known as CHARGE syndrome cases, which include severe and life-threatening heart malformations. Credit: UAB BIRMINGHAM, Ala. – Research by Kai Jiao, M.D.,

Protein 52
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Molecular alteration may be cause — not consequence — of heart failure

Scienmag

Clinicians and scientists have long observed that cells in overstressed hearts have high levels of the simple sugar O-GlcNAc modifying thousands of proteins within cells.

Protein 40
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RNA modification may protect against liver disease

Scienmag

May also explain liver fat differences among men & women Credit: Sallam Lab/UCLA FINDINGS A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells’ protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver (..)

RNA 95