XTalks

JUNE 28, 2023

DMD is caused by the absence of dystrophin, a protein that helps maintain the integrity of muscle cells. The therapy’s strong clinical safety data helped Sarepta secure the approval, as among 85 patients, only 13 serious side effects and no deaths or discontinuations due to adverse events were reported.

Gene Therapy 98

Gene Therapy Gene Protein FDA Approval 98

Drug Discovery World

DECEMBER 14, 2023

The new hub will become a part of the already thriving life sciences sector in the Glasgow area, most of which is centred around the university, the Cancer Research UK Scotland Institute and the BioCity cluster, making Glasgow and its surrounds one of the most important regions for drug discovery and development in the UK.

Drugs 75

Drugs Life Science Research Scientist 75

XTalks

NOVEMBER 23, 2020

The global trials are assessing the safety and efficacy of the vaccine in individuals aged 18 years or over from diverse racial and geographic groups who are healthy or have stable underlying medical conditions. Oxford-AstraZeneca COVID-19 Vaccine Induces Immune Responses in Early Clinical Trials.

Vaccination 97

Vaccination Vaccine Clinical Trials Clinical Trials 97

XTalks

AUGUST 18, 2023

Izervay is the only approved treatment for geographic atrophy that has demonstrated a significant decrease in the rate of geographic atrophy progression at the 12-month primary endpoint, based on results from two rigorous Phase III clinical trials. Izervay contains avacincaptad pegol sodium, an effective complement C5 inhibitor.

FDA Approval 52

FDA Approval Drugs Clinical Trials Clinical Trials 52

XTalks

MAY 1, 2023

XTALKS WEBINAR: Patient-Centricity in Clinical Trials Sites — The Trinity of Patient, Sites and Sponsors Live and On-Demand: Monday, June 12, 2023, at 10am EDT (4pm CEST/EU-Central) Register for this free webinar to learn how the Patient Concierge program increases study participants’ engagement and decreases dropout.

FDA Approval 89

FDA Approval Gene Genetics Protein 89

XTalks

SEPTEMBER 8, 2020

AZD1222 is now in Phase III clinical trials which will enroll approximately 30,000 adult volunteers in 80 states in the US, to determine whether the vaccine can help prevent symptomatic coronavirus disease from spreading. The genetic material contains SARS-CoV-2 spike protein.

Manufacturing 83

Manufacturing Vaccination Vaccine Allergies 83

Drug Discovery World

OCTOBER 20, 2022

Kawasaki King Skyfront is an R&D center with a focus on life science and environmental fields—and the realisation of open innovation projects. CELLINK Corporation, the Japanese subsidiary, was established in 2020 in Kansai, a region renowned for life sciences research facilities and corporations 3. .

Development 52

Development Drugs Life Science Marketing 52

XTalks

JUNE 16, 2021

Novavax shared the latest data from its ongoing late-stage COVID-19 vaccine trial, which shows that its yet-to-be authorized shot provides 100 percent protection against moderate and severe disease and has an overall efficacy of 90.4 Related: Latest Data from Novavax COVID-19 Vaccine Trial Involving B.1.351

Vaccination 98

Vaccination Vaccine Protein Trials 98

XTalks

MARCH 10, 2023

It is caused by a mutation in the FXN gene , which is responsible for the production of the protein frataxin. Usually diagnosed during adolescence ( 10-15 years ), Friedreich’s ataxia shortens life expectancy, causing the patient to be wheelchair bound within the first 10 to 20 years of diagnosis and most often leading to death.

FDA Approval 52

FDA Approval Engineer Clinical Trials Clinical Trials 52

XTalks

AUGUST 17, 2020

Cue Biopharma is a Cambridge, Massachusetts-based clinical-stage biotechnology company that is focused on developing injectable immune biologics using its proprietary Immuno-STAT (Selective Targeting and Alteration of T cells) platform. protein-based biologics) and vaccine treatments. Cell-Based Immunotherapy vs. Immune Biologics.

Protein 98

Protein Engineer Immune Response In-Vivo 98

XTalks

NOVEMBER 10, 2023

The US Food and Drug Administration (FDA) has approved Takeda Pharmaceuticals’ Adzynma, the first recombinant protein product for prophylactic (preventive) or on‑demand enzyme replacement therapy (ERT) in adult and pediatric patients with congenital thrombotic thrombocytopenic purpura (cTTP), an ultra-rare blood clotting disorder.

FDA Approval 59

FDA Approval Gene Therapy Gene Clinical Trials 59

XTalks

JANUARY 27, 2021

For this, sera were used from eight participants (aged 18-55 years) from the Phase I clinical trial of Moderna’s vaccine study who received two 100 µg doses of mRNA-1273. The two variants studied have mutations in the spike protein of SARS-CoV-2, with 17 mutations in B.1.1.7 Neutralization of the B.1.1.7 1.351 variant.

Vaccination 52

Vaccination Vaccine In-Vitro Protein 52

The Pharma Data

JANUARY 18, 2021

In-licensed from Merck KGaA, Darmstadt, Germany , atacicept has been studied previously in autoimmune diseases and shown to reduce autoantibodies in a dose-dependent fashion with once-weekly subcutaneous dosing and has a well-established and acceptable clinical safety profile. “Dr. .” For more info, please visit abingworth.com.

Development 52

Development Life Science Protein Clinical Development 52

XTalks

APRIL 26, 2021

The vaccine is protein-based and contains an adjuvant (MM), a component that helps generate a stronger immune response, that was developed by Novavax. Malaria Vaccine Phase II Trial. Oxford researchers developed the R21/MM malaria vaccine in collaboration with the Serum Institute of India and biotech company Novavax.

Vaccination 105

Vaccination Vaccine Immune Response Trials 105

XTalks

SEPTEMBER 15, 2020

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. islet cells of the organ, giving rise to the disease.

Vaccination 103

Vaccination Vaccine Insulin Trials 103

The Pharma Data

DECEMBER 20, 2020

21, 2020 (GLOBE NEWSWIRE) — SELLAS Life Sciences Group, Inc. In the first study, a phase 1/2 ‘basket’ trial of GPS in combination with the checkpoint inhibitor pembrolizumab (Keytruda), which is conducted under a Clinical Trial Collaboration and Supply Agreement with Merck & Co., NEW YORK, Dec.

Life Science 52

Life Science Immune Response Trials Clinical Trials 52

XTalks

FEBRUARY 8, 2024

Diabetes remains a critical global challenge, affecting millions of lives and commanding significant attention from the medical, life sciences and pharmaceutical sectors. The efficacy and safety of Rybelsus in reducing blood sugar in patients with type 2 diabetes were investigated in various clinical trials.

Sales 52

Sales Insulin FDA Approval Drugs 52

The Pharma Data

DECEMBER 23, 2020

Additionally, Phase 1 clinical data found INO-4800 to have a favorable safety and tolerability profile with no serious adverse events reported; only six Grade 1 adverse events (AEs) were observed, primarily minor injection site reactions. ” Findings from the Phase 1 Clinical Trial. mg and 2.0

DNA 40

DNA Vaccination Vaccine Immune Response 40

The Pharma Data

JANUARY 6, 2021

About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Based on its proprietary technology, the company has built a deep clinical pipeline across the areas of prophylactic vaccines, cancer therapies, antibody therapies, and the treatment of rare diseases.

Vaccination 52

Vaccination Vaccine Development Marketing 52

Pharmaceutical Technology

NOVEMBER 22, 2022

According to CEPI: “Achieving the 100 Days Mission would give the world a fighting chance of containing a future outbreak before it spreads to become a global pandemic.”. The mission was first put forward during the UK’s G7 Presidency of June 2021, with support from representatives of the life sciences industry.

Manufacturing 130

Manufacturing Vaccination Vaccine RNA 130

pharmaphorum

SEPTEMBER 18, 2020

The same year, AZ also entered into its third collaboration agreement with Astex Therapeutics, this time to develop small-molecule protein kinase B (PKB) to further contribute in the fight against cancer. AstraZeneca’s first acquisition following its creation was of KuDOS Pharmaceuticals, a UK biotech company, for £120 million in 2005.

Pharma Companies 116

Pharma Companies Sales Vaccination Vaccine 116

Drug Discovery World

FEBRUARY 5, 2024

In life sciences, as well as being used to draft articles, the technology can assist researchers in generating scientific content or summaries. For generative AI to be trusted as a reliable ‘source of truth’ in life sciences applications, knowledge sources need be both transparent and validated, along with how connections have been made.

Life Science 59

Life Science Drugs Marketing Clinical Trials 59

XTalks

AUGUST 2, 2023

It contains the antiviral medications nirmatrelvir and ritonavir. Johnson & Johnson’s Top 5 Best-Selling Drugs of 2022: 1) Stelara (ustekinumab) Stelara is an immunosuppressant biologic therapy that blocks the IL-12 and IL-23 proteins that play a role in plaque psoriasis and Crohn’s disease. billion in 2022. billion in 2022, a 6.45

Sales 98

Sales Manufacturing FDA Approval Life Science 98

Drug Discovery World

AUGUST 10, 2022

To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells. CAR is a fusion protein composed of an extracellular antibody fragment that recognises antigens and an intracellular domain that directs the T cell to the tumour. Identifying the right CAR T cell target.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

Drug Discovery World

NOVEMBER 30, 2023

This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It The next presentation attended in this track was the keynote presentation, which was given by Kate Smith, PhD, Head of UK Protein & Cell Sciences at GSK. GSK has developed high-throughput mammalian and E.

Antibody 59

Antibody Protein Engineer In-Vivo 59

XTalks

MAY 15, 2023

Protalix BioTherapeutics focuses on the production, development and commercialization of recombinant therapeutic proteins. He also highlighted that the development of Elfabrio marked a significant milestone in the quest for a durable therapy for Fabry disease, supported by promising results from clinical trials.

FDA Approval 98

FDA Approval Gene Genetics Clinical Trials 98

XTalks

AUGUST 7, 2023

He also thanked the 500 patients, caregivers, investigators and healthcare professionals involved in the Phase III trials and stated that Verrica’s commercial team is actively preparing for the product’s commercial launch in September 2023. Participants in these trials ranged in age from two to 60, with a median age of six.

FDA Approval 98

FDA Approval Dermatology Trials Clinical Trials 98

XTalks

FEBRUARY 7, 2023

Rugo, MD, professor of Medicine and Director, Breast Oncology and Clinical Trials Education at the UCSF Helen Diller Family Comprehensive Cancer Center, US and principal investigator of the TROPiCS-02 study, in the press release. Trodelvy contains a monoclonal antibody linked to the anticancer cytotoxic drug SN-38.

HR 52

HR Hormones FDA Approval Antibody 52

XTalks

DECEMBER 14, 2021

The quadrivalent influenza vaccine candidate, mRNA-1010, is targeted against hemagglutinin (HA) proteins from four seasonal influenza viruses, which include two influenza A subtypes, H1N1 and H3N2, and two influenza B subtypes, Yamagata and Victoria. These strains of the virus were recommended by the World Health Organization (WHO).

Vaccination 98

Vaccination Vaccine Immune Response Antibody 98

XTalks

OCTOBER 26, 2023

The Flu versus COVID-19: Virology and Vaccines SARS-CoV-2 versus Influenza Virology Viruses contain genetic material that can either be RNA or DNA. This means COVID-19 can quickly produce viral proteins once inside the host cell, which may make its replication cycle faster than influenza. remains the dominant variant.

Vaccination 105

Vaccination Vaccine RNA Manufacturing 105

The Pharma Data

DECEMBER 8, 2020

They contain proteins, nucleic acids and metabolites, which carry information from secreting to receiving cells. Exosomes carry information of secreting to receiving cells utilising proteins, nucleic acids and metabolites. . EVOTEC AND SARTORIUS FORM CONSORTIUM TO SUPPORT CUREXSYS’ € 8.2 M SEED FINANCING ROUND.

Manufacturing 52

Manufacturing Containment Life Science Production 52

XTalks

JANUARY 31, 2022

The third group will contain unimmunized individuals who will get three doses of the omicron shot. However, the company noted that cell-mediated immunity was not significantly impacted by omicron, as 85 percent of epitopes in the spike protein have been observed to be recognized by CD8+ T cells.

Vaccination 98

Vaccination Vaccine Trials Antibody 98

Drug Discovery World

OCTOBER 21, 2022

Simultaneously, the capacity to conjugate fluorescent molecules to proteins to better characterise biological systems has evolved accordingly, enabling the proliferation of highly specific tools to interrogate cells. Setting up proper single-colour controls is critical to obtaining good compensation and spectral unmixing matrices.

Reagent 52

Reagent Antibody Drugs Protein 52

Drug Discovery World

APRIL 9, 2024

ImmunoBrain Checkpoint (IBC) is currently dosing patients in a clinical trial with its monoclonal antibody for Alzheimer’s disease (AD). MS : We are currently dosing patients in a Phase I clinical trial to evaluate our lead asset, IBC- Ab002, for safety, tolerability, and pharmacokinetics in patients with early-onset AD.

Antibody 59

Antibody Clinical Trials Clinical Trials Protein 59

Pharmaceutical Technology

APRIL 24, 2023

“Biologics products may contain proteins that control the action of other proteins and cellular processes, genes that control production of vital proteins, modified human hormones, or cells that produce substances that suppress or activate components of the immune system.

Contract Manufacturing 130

Contract Manufacturing Manufacturing Protein Sales 130

XTalks

FEBRUARY 3, 2021

Biotech company Novavax (Nasdaq: NVAX ) reported that its protein-based vaccine demonstrated an efficacy of 89.3 percent in Phase III trials in the UK, in which over 50 percent of cases were attributable to the B.1.1.7 Novavax’s Protein Vaccine. The protein is produced in insect cells and then purified.

Vaccination 103

Vaccination Vaccine Trials Protein 103

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. By the end of August, the World Health Organization (WHO) counted 33 vaccine candidates in some stage of clinical trial evaluation. The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein.

Vaccination 92

Vaccination Vaccine Antibody Life Science 92