Containment Doctors Gene Protein 
Drug Discovery World
MAY 29, 2024
Marc Hummersone, Senior Director of Research and Development (R&D) at Astrea Bioseparations, shares insight on the challenges and opportunities in cell and gene therapy (CGT) with DDW’s Megan Thomas. So yes, you’ve got protein, but it’s not going to transfect or infect.” That’s not the case in CGT.”
The Pharma Data
FEBRUARY 12, 2022
They took a close look at the role of a protein called MFSD1 – the mammalian relative of a protein they had previously identified as affecting cell migration in fruit flies. Therefore, first author Marko Roblek from the Siekhaus group created mouse cancer cells lacking the protein. Protein prevents detachment.
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XTalks
AUGUST 10, 2021
Moreover, studies show that saliva samples can contain a marginally higher SARS-CoV-2 viral load compared with nasopharyngeal samples (shown in a study involving hospitalized patients), and that the virus can be detected in saliva for a greater number of days post-infection. A porous membrane was engineered to capture RNA on its surface.
XTalks
FEBRUARY 11, 2021
After several such Nobel Prize snubs for female scientists, 2020 saw the Nobel Prize in Chemistry go to a female scientist duo for the first time for their revolutionary discovery of the CRISPR-Cas9 gene editing system. She was actually able to use the research for her doctoral thesis, graduating with a doctorate from Cambridge in 1945.
Advarra
MARCH 10, 2023
Red blood cells contain hemoglobin, a protein that carries oxygen. These are reasons for biotech organizations to renew a focus on improving diversity in clinical research while bringing more sickle cell gene therapies to market. A visit to a podiatrist and family doctor yielded less than satisfactory diagnoses.
The Pharma Data
JANUARY 4, 2021
TIGIT and PD-L1 are proteins that play a role in suppression of the immune system. Tiragolumab is a monoclonal antibody designed to bind with TIGIT, a protein receptor on immune cells. Tecentriq is a monoclonal antibody designed to bind with a protein called PD-L1. Dual blockade of the TIGIT and PD-L1 pathways.
The Pharma Data
DECEMBER 3, 2020
Targeted Augmentation of Nuclear Gene Output (TANGO) of SCN1A Reduces Seizures and Rescues Parvalbumin Positive Interneuron Firing Frequency in a Mouse Model of Dravet Syndrome. protein expression by leveraging the non-mutant (wild-type) copy of the SCN1A gene to restore physiological Na V 1.1 Translational Research / 2B.
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