pharmaphorum

MARCH 12, 2021

The UK regulator has authorised Eli Lilly’s targeted cancer drug Retsevmo for tumours with RET fusion positive lung cancers and thyroid cancers, which the company said could herald a new era of genomic medicine for the NHS. billion collaboration with Bluebird Medicines to develop a rival RET inhibitor, pralsetinib.

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Drug Discovery World

DECEMBER 29, 2023

Known as ‘CReATiNG’ (Cloning Reprogramming and Assembling Tiled Natural Genomic DNA), the method offers a simpler and more cost-effective approach to constructing synthetic chromosomes. The thing about most synthetic genomics research is that it involves building chromosomes or genomes from scratch using chemically synthesised DNA pieces.

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pharmaphorum

JUNE 13, 2022

Canary Wharf’s bid to become a new hub for the life sciences sector in the UK has been given a boost following the decision by Genomics England to relocate to the development. It was announced three years after the European Medicines Agency (EMA) relocated from the site to Amsterdam as a result of the UK’s exit from the EU.

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Pharmaceutical Technology

JUNE 20, 2023

The Department of Health Abu Dhabi (DoH) has signed a memorandum of understanding with integrated healthcare company M42 and AbbVie Biopharmaceuticals to advance personalised medicine and genomics in the city. M42 was created through the combination of Mubadala Health and G42 Healthcare.

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Pharmaceutical Technology

JUNE 16, 2023

Benefiting from Abu Dhabi’s improved genomics capabilities, the deal seeks to expand research into genomic medicine and genetic diseases to provide patients in the UAE and beyond with improved access to new tools and treatments.

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Drug Discovery World

JUNE 21, 2023

The European Confederation of Pharmaceutical Entrepreneurs (EUCOPE), Exact Sciences, Guardant Health, Illumina, MSD and Novartis have come together to launch the European Coalition for Access to Comprehensive Genomic Profiling (ECGP).

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pharmaphorum

OCTOBER 31, 2022

Verge Genomics has joined a select group of biotechs who have taken a drug discovered and developed using artificial intelligence into human testing. Since then others have followed suit, including BenevolentAI with its BEN-2293 candidate for atopic dermatitis and Insilico Medicine with idiopathic pulmonary fibrosis therapy SM001-055.

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Genome Genomics Drugs RNA 132

Drug Discovery World

MAY 5, 2023

Anthony Schmitt , PhD, Senior Vice President, Science at Arima Genomics, discusses the applications of 3D genomics in cancer research. But what about the patients whose genomic tests do not identify a cancer driver matched to an existing targeted therapy? with regards to detecting cancer driver mutations.

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Genome Genomics Gene Genetics 52

Scienmag

JULY 11, 2022

SAN DIEGO, Calif.

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Drug Discovery World

AUGUST 3, 2023

This is the latest episode of the free DDW narrated podcast, “What lies in the future for genomics and big data?”, and “ Why a recent advancement is a giant leap for human genomics ”. Listen here: The post New podcast on the future for genomics and big data appeared first on Drug Discovery World (DDW).

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pharmaphorum

OCTOBER 19, 2022

million ($40 million) first-round financing that will be used to explore so-called ‘dark’ regions of the human genome. M Ventures’ Dr Bauke Anninga said that that the startup has a “differentiated platform technology has the potential to fundamentally shift the way we discover and develop precision medicines.

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Genome Genomics Gene Gene Expression 57

Drug Discovery World

OCTOBER 26, 2022

A study by the Qatar Genome Research Consortium, led by Dr Lotfi Chouchane from Weill Cornell Medicine-Qatar, has reported the first landscape of cancer germline mutations – hereditary mutations – in the Qatari population. . These variants increase the risk of developing breast cancer in women and prostate cancer in men. .

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Pharmaceutical Technology

APRIL 12, 2023

Foundation Medicine has announced it will supply a tissue-based test as a companion diagnostic for Bristol Myers Squibb’s (BMS) recently acquired ROS1/TRK inhibitor repotrectinib. Repotrectinib has been developed to combat cancer resistance to existing therapies and exert consistent anti-tumor activity.

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Pharmaceutical Technology

SEPTEMBER 1, 2022

Guardant Health has extended a partnership with Merck KGaA, Darmstadt, Germany, to aid in expediting precision oncology therapeutics development. Under the collaboration, the companies will use the GuardantINFORM real-world evidence (RWE) platform to boost works for developing Merck’s precision cancer pipeline.

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Drug Discovery World

NOVEMBER 7, 2022

A new study led by Medical Research Council-funded researchers from UCL has found that tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases. . Consequently, the UK has established itself at the forefront of diagnostic whole genome sequencing. Context .

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AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2022

As drug companies have embarked on an initiative to launch affordable medicines for rare diseases in India, experts have called for using pharmacogenetics to develop treatments and whole genome sequencing to identify etiologies.

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Roots Analysis

FEBRUARY 27, 2024

The global genome editing market is anticipated to grow at a CAGR of 12.6% The global genome editing market is anticipated to grow at a CAGR of 12.6% The biopharmaceutical pipeline includes close to 500 gene therapies , several of which are being developed based on CRISPR technology. during the forecast period 2023-2035.

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Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. The tide has been turning in the worlds of diagnostics and drug development. A recent flurry of announcements indicates increasing interest and trust from major public health organisations in the power of genomics.

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Medical Xpress

MARCH 27, 2023

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

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Genome Genomics Scientist Genetics 75

Drug Discovery World

JULY 15, 2022

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

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Genome Genomics DNA Containment 52

Drug Discovery World

MARCH 27, 2023

Genomics is driving a revolution in drug development and, in the long run, the state of public healthcare. Without a solution, the sector risks jeopardising critical public trust in data-sharing. The dilemmas of data The last 20 years have seen tremendous growth in human genomics.

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Genome Genomics Research Scientist 52

Roots Analysis

FEBRUARY 15, 2022

Presently, there are several companies and universities, which are exploring the potential of different gene editing technologies beyond CRISPR for basic research, and the development of gene editing solutions. Genome Editing is a way of making changes in the DNA. Type of Genome Editing: Zinc-Finger Nuclease.

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Drug Discovery World

APRIL 10, 2023

India is traditionally known as ‘the pharmacy of the world’ due to its huge pharmaceuticals manufacturing capacity and high quantity of exports, particularly generic medicines and vaccines. Industry has grown tremendously in the last five years with timely policy interventions, infrastructure development and thrust on education and training.

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Genome Genomics Drugs Life Science 52

XTalks

NOVEMBER 10, 2020

For more information on tackling this “genomic analysis bottleneck,” watch this on-demand webinar. HS: Due to the heterogeneity of the rare disease population, there are many relevant gene lists, and the genomic data analysis of these patients covers almost 2,000 different genetic targets. ” or “Why is my child different?”

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Genome Genomics Medicine Genetic Disease 98

Drug Discovery Today

NOVEMBER 2, 2022

and Oxford, UK – November 2, 2022 – ROME Therapeutics and Enara Bio, two leading biotechnology companies focused on developing novel medicines driven by insights to the dark genome, today announced that they will host the inaugural Dark Genome Symposium on Monday, November 7, 2022 at ROME’s headquarters in Boston.

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Scienmag

AUGUST 7, 2020

Credit: UTHSC Neil Hayes, MD, MS, MPH, division chief of Hematology and Oncology at the University of Tennessee Health Science Center, is among recipients of the 2020 Team Science Awards from the American Association for Cancer Research (AACR) for his contributions to developing The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to (..)

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Pharmaceutical Technology

OCTOBER 11, 2022

Biotechnology company Ochre Bio has raised $30m in a Series A financing round to develop RNA therapies for chronic liver diseases. Ochre Bio will also expand its platforms for drug discovery and development that include a new RNA chemistry and an exploratory platform for expanding its research to more liver diseases.

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The Pharma Data

OCTOBER 26, 2021

The AVENIO Tumor Tissue Comprehensive Genomic Profiling (CGP) Kit is the first jointly-developed product that brings together the expertise and reach of Roche with Foundation Medicine’s pioneering leadership in genomic science. To treat cancer effectively, we must understand what drives it at a molecular level.

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Genome Genomics Research Medicine 52

STAT News

OCTOBER 3, 2022

A Swedish scientist won the 2022 Nobel Prize in medicine or physiology on Monday for his groundbreaking research into the evolutionary history of humankind. Pääbo unlocked scientists’ understanding of how genes from these extinct relatives have been passed down to present-day humans.

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Medicine Contamination Research DNA 142

Scienmag

SEPTEMBER 7, 2020

Researchers have developed a statistical model that uses genomic data to predict the risk of developing cancer of the oesophagus Credit: Spence Phillips / EMBL-EBI Oesophageal cancer is the eighth most common cancer worldwide. It often develops from a condition called Barrett’s oesophagus.

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Genome Genomics Development Research 52

pharmaphorum

MARCH 24, 2022

GlaxoSmithKline has thrown its financial and drug development weight behind LifeMine Therapeutics, a US startup that aims to find new therapeutics from fungi – widely regarded as an underexplored resource of biologically-active compounds. The post GSK partners LifeMine on fungi-derived medicines appeared first on.

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Medicine Genome Genomics Engineer 96

STAT News

JULY 29, 2022

Precision medicine — tailoring a treatment to an individual’s disease — requires understanding the individual’s biological characteristics. More than 80% of genomics studies have been conducted in people of European descent. Read the rest…

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Medicine DNA Genome Genomics 111

BioPharma Reporter

MAY 23, 2024

Oxford BioDynamics, a biotech company specializing in precision medicine tests via the EpiSwitch 3D genomics platform, has partnered with the Goodbody Clinic, a provider of private health testing services.

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Genome Genomics Medicine Development 52

The Pharma Data

MARCH 7, 2022

Decision Regarding Slick-Haired Cattle is Agency’s First Enforcement Discretion Decision for an Intentional Genomic Alteration in an Animal for Food Use. director of the FDA’s Center for Veterinary Medicine. “It IGAs are alterations made using molecular technologies that introduce changes to the genome of an animal.

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Drug Discovery World

JANUARY 11, 2024

This is the latest episode of the free DDW narrated podcast, titled “Revolutionary technology for drug discovery and development” which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. The post New podcast: Revolutionary technology for drug discovery and development appeared first on Drug Discovery World (DDW).

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Development Drugs Genome Genomics 59

Drug Discovery World

APRIL 24, 2024

The strategic partnership will combine Variant Bio’s genomic discovery capabilities and VB-Inference platform with Evotec’s knowledge of antifibrotic drug discovery. They have the experience and track record in converting breakthrough science into medicines that matter for patients.”

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Development In-Vivo In-Vitro Genome 52

Pharmaceutical Technology

SEPTEMBER 22, 2022

You have just received the results from your whole genome sequencing test, offered through your public health provider, and discovered that you have a 75% chance of developing a rare form of cancer. If a vaccine is not yet available, and the cancer has begun to grow, personalised medicine will be your best therapeutic solution.

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