pharmaphorum
JANUARY 29, 2021
‘Cutting edge’ is, for once, a truly apt description when it comes to gene editing – both because the field is pushing medicine into areas we might never have dreamed possible, and because these technologies involve literally cutting DNA at a specific point in the genome. Zinc fingers. That would just slow the whole field down.
Fierce Pharma
DECEMBER 21, 2023
As Vertex Pharmaceuticals and CRISPR Therapeutics lay the groundwork for the launch of their CRISPR-based gene-editing therapy Casgevy, one doctor who treats sickle cell disease patients is already | As Vertex Pharmaceuticals and CRISPR Therapeutics lay the groundwork for the launch of their world-first CRISPR-based gene therapy Casgevy, one doctor (..)
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Drug Discovery World
JANUARY 17, 2023
The study, led by OSU Associate Professor of Pharmaceutical Sciences Gaurav Sahay, Oregon State doctoral student Marco Herrera-Barrera, and Oregon Health & Science University Assistant Professor of Ophthalmology Renee Ryals, was published in Science Advances. .
Drug Discovery World
NOVEMBER 1, 2023
At the moment, we are focused on gene editing tools, and specifically CRISPR nucleases, trying to design strategies that allow us to use them more safely and effectively. Our goal is to develop strategies that allow us to understand how they work and how they find their targets, so we can hopefully improve them.
pharmaphorum
FEBRUARY 16, 2022
Having a third functional cure of HIV nevertheless does give pointers to how a more widely applicable cure might be developed in the future, for example using gene-editing drugs to introduce CCR5?32 Sangamo was working on a treatment based on autologous (patient-derived) stem cells and T cells that were gene-edited to carry the CCR5?32
Drug Discovery World
MARCH 8, 2024
This inspired her to change direction, first by investigating the role of Epstein-Barr Virus in epithelial cancers during her PhD, and subsequently TGFβ-signalling in breast cancer during her post-doctoral career. Read the interview.
Drug Discovery World
NOVEMBER 27, 2023
Upstream cell line development has seen notable progress with recent advances in cell line engineering, particularly in enhancing gene of interest integration specificity, clone selection, and production efficiency. Next-generation engineering tools, such as gene editing have enabled knock-out cell lines with enhanced characteristics.
Expert insights. Personalized for you.
145 
Let's personalize your content