Roots Analysis

OCTOBER 2, 2023

Owing to their unique size and physicochemical properties ( surface roughness, surface area, surface energy, crystal structure and shape ), nanoparticles can be widely used as a contrasting agent in medical imaging, a vesicle to cross the blood-brain barrier and a carrier for targeted delivery of genes / drugs, proteins, vaccines and antibiotics.

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Drug Delivery Drugs Bioavailability Marketing 40

The Pharma Data

JUNE 7, 2023

Bayer strengthens gene therapy portfolio with lipid nanoparticle technology from Acuitas Therapeutics Bayer AG is joining forces with Acuitas Therapeutics, Inc., a biotechnology company specializing in the development of lipid nanoparticle (LNP) delivery systems for molecular therapeutics. Financial details were not disclosed.

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Gene Therapy Gene Gene Editing In-Vivo 40

Pharmaceutical Technology

APRIL 4, 2023

The company will undertake a technology transfer and feasibility study for a drug product focused on the treatment of IPF at its centre of cell and gene expertise in Milan, Italy. Cell & Gene Therapy coverage on Pharmaceutical Technology is supported by Cytiva.

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pharmaphorum

SEPTEMBER 23, 2020

Sixfold Bioscience in partnership with Medicines Discovery Catapult, has been given the green light, through the award of an Innovate UK Smart Grant to test a pioneering system designed to deliver drugs directly to cancerous cells, without impacting the healthy cells around it.

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Pharmaceutical Technology

APRIL 21, 2023

When combined with mRNA therapeutic molecules developed by LG Chem, the pre-made drug delivery formulation helps to simplify and improve the combination process. This is expected to shorten the development time of new drugs and to support personalised treatments.

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Development Gene Therapy Drug Delivery Gene 130

Drug Discovery World

JUNE 22, 2023

“This is part of our long-term business strategy of leveraging exosome-mediated delivery to create and enable genetic medicines such as gene therapy and genome editors”. The post Evox Therapeutics acquires exosome AAV technology from Codiak appeared first on Drug Discovery World (DDW).

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Gene Therapy Gene Editing Drug Delivery Gene 52

pharmaphorum

JULY 15, 2022

SAE Media Group’s 5th Annual Ophthalmic Drugs Conference will explore advancements in ophthalmic treatments and variety of novel drugs, which are showing good clinical trial data. Drug delivery will also be an important aspect of the agenda, with advancements in novel technologies. And many more!

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Gene Therapy Drugs Drug Delivery Clinical Trials 52

Delveinsight

MARCH 2, 2021

HitGen & UPPTHERA Collaborate for Drug Delivery Research. HitGen has entered into a collaboration for drug discovery research with UPPTHERA to identify small molecule Hits against previous known-to-be undruggable targets and novel E3 ligase.

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Drug Delivery Research Drugs Gene Editing 40

Drug Discovery World

JANUARY 17, 2023

Limitations of AAV gene therapy . They will lead research into using LNPs to deliver a gene editing tool that could delete bad genes in the photoreceptor cells and replace them with correctly functioning genes. . Sahay and Ryals have received a $3.2

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Gene Editing Gene Gene Therapy Genetics 98

BioSpace

NOVEMBER 17, 2022

Editas Medicine is pausing its ocular gene therapy program after demonstrating a favorable safety profile and seeking a potential partner to develop EDIT-101, the company announced Thursday.

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Gene Therapy Gene Gene Editing Medicine 42

Pharmaceutical Technology

NOVEMBER 21, 2022

Additionally, the wide-ranging expertise of RVAC in mRNA, vaccine and drug delivery technologies, and its capabilities in research and development (R&D), biopharmaceutical manufacturing, clinical development and marketing is leveraged under the partnership. “We

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XTalks

JUNE 14, 2023

XTALKS WEBINAR: Drug Delivery — Evaluating Off-The-Shelf and Novel Drug Delivery Solutions Live and On-Demand: Tuesday, July 11, 2023, at 1pm EDT (10am PDT) Register for this free webinar to learn about important tradeoffs when considering an off-the-shelf (OTS) drug delivery platform vs. novel development.

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Gene Silencing Drug Delivery FDA Approval RNA 97

pharmaphorum

APRIL 28, 2022

Harness Safe & Efficacious Lipid-Based Delivery for Novel Therapeutics Beyond RNA & Hepatic Tissue. The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery.

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RNA Drug Delivery Engineer Gene Therapy 52

pharmaphorum

APRIL 29, 2021

Uncover advances in CNS gene therapy , new generation vectors for intravenous delivery, and the challenges of scaling up for CNS delivery beyond highly specialized centers. The high concentration of scientists who face similar challenges makes this Summit so essential to the development of the field.

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Drug Delivery Gene Therapy In-Vivo Antibody 52

Roots Analysis

AUGUST 8, 2023

Furthermore, a wide variety of drugs and macromolecules, including DNA , proteins, and imaging agents, can be encapsulated in liposomal vesicles due to their unique ability to entrap both lipophilic and hydrophilic substances. The various therapeutic applications of liposomes in drug delivery have been highlighted in the figure.

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Drug Delivery Systems Drug Delivery Drugs In-Vivo 52

BioPharma Reporter

MAY 4, 2022

CPhI North America 2022 host city Philadelphia is set to become one of the worldâs biggest cell and gene therapy manufacturing hubs. But itâs just one of many centers of innovation that are helping drive the US pharma and biopharma industry.

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Gene Therapy Gene Manufacturing Drug Delivery 98

Scienmag

JANUARY 8, 2021

The research answers a long-standing biological question and could have implications for the timing of drug delivery, biotechnology, and […]. Now research reveals that bacteria too have internal clocks that align with the 24-hour cycle of life on Earth.

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Bacteria Drug Delivery Research Drugs 66

Roots Analysis

FEBRUARY 26, 2024

However, certain biological targets have long eluded drug development efforts. Scientific literature suggests that the RAS gene is mutated across about 30% of cancer types. One such target is Ras family, which has been identified to play a critical role in oncogenesis.

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Drug Delivery Systems Marketing Drug Delivery Development 52

pharmaphorum

NOVEMBER 7, 2022

The conference will explore advancements in ophthalmic treatments and variety of novel drugs, which are showing great clinical trial data. There will also be a specific focus on drug delivery along with advancements in novel technologies. The conference is co-chaired by Mitchell A.

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Drugs Clinical Trials Clinical Trials Gene Therapy 52

pharmaphorum

NOVEMBER 1, 2022

The new master agreement, covering another five years, will foster research on genetic medicines, intrathecal delivery of therapeutics into the spinal canal or subarachnoid space of the brain, and the use of nanoparticles to improve drug delivery.

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Drug Discovery World

APRIL 3, 2023

As the industry’s awareness of alternatives to traditional antibodies continues to grow, there is increasing demand for these alternatives, which we are seeing particularly within the therapeutic sector, to enable targeted therapeutics and enable the emerging gene therapy market. DS: The company now has clients across big pharma.

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The Pharma Data

SEPTEMBER 1, 2021

. “Doctors often treat patients who have rheumatoid arthritis with injections or infusions of anti-inflammatory biologic drugs, but those drugs can cause significant side effects when delivered long enough and at high enough doses to have beneficial effects,” said senior investigator Farshid Guilak, PhD, the Mildred B.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

Roots Analysis

OCTOBER 5, 2023

Driven by the increasing need for safe and efficient medical devices and drug delivery systems, the pharmaceutical polymers / medical grade polymers domain is advancing significantly. There has been a rise in the development of polymers for biopharma with improved biocompatibility, biodegradability and functionality.

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Drug Discovery World

NOVEMBER 30, 2022

The companies hope to meet the demand for a large-scale, high-efficiency purification technology that overcomes critical issues associated with the production of clinical-quality exosomes as delivery vehicles for gene-based therapeutics. .

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Production Immune Response RNA Gene 52

Drug Discovery World

NOVEMBER 17, 2022

The Brady lab has been finding antibacterial genes in soil and growing them within more lab-friendly bacteria. Most antibiotics are derived from genetic sequences locked within so-called biosynthetic gene clusters, which are genes that function as a unit to collectively code for a series of proteins.

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Bacteria Engineer Gene Genetics 52

Drug Discovery World

FEBRUARY 5, 2024

This is EXO Biologics’ lead MSC-based exosome candidate for prevention of Bronchopulmonary Dysplasia (BPD) in preterm newborns. “The potential of exosomes continues to be demonstrated across the cell and gene therapy sector.

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Clinical Trials Clinical Trials Manufacturing Gene Therapy 52

Roots Analysis

MARCH 13, 2022

In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines and gene therapies), by the US FDA, have steadily risen. Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. Our Social Media Platform.

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Manufacturing Drug Delivery Marketing Drug Delivery Systems 52

Drug Discovery World

FEBRUARY 16, 2023

The company’s protein nanoparticle (PNP) genetic medicine delivery platform is based on the discovery of endogenous, human proteins derived from retroelements that can self-assemble to form capsid-like structures and which can package and transfer nucleic acid cargo.

Genetics 52

Genetics Medicine Gene Editing In-Vivo 52

Roots Analysis

MARCH 9, 2022

In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines, and gene therapies), by the US FDA, have steadily risen. Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry.

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Manufacturing Marketing Contract Manufacturing Protein 52

XTalks

AUGUST 30, 2022

One of the biggest challenges with developing therapies to treat CNS disorders is the delivery of systemically administered investigational products (IPs) to the brain, which is limited by the blood-brain barrier. Some methods of direct CNS administration include intrathecal, intraparenchymal and intracerebroventricular (ICV) delivery.

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Trials Drug Delivery Drugs Gene 83

Delveinsight

FEBRUARY 25, 2021

Beam adds to drug delivery stable with USD 120 Million GuideTx buy. The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site.

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DNA In-Vivo Genetics Medicine 52

Roots Analysis

OCTOBER 13, 2023

Over the last two decades the pharmaceutical industry has observed a paradigm shift from conventional drug delivery strategies to more enhanced, potent, and targeted therapeutics. This led the researchers to find alternative pathways and drug delivery strategies to enhance the potent delivery of the drug to the site of action.

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Drugs Antibody RNA Genetics 40

The Pharma Data

APRIL 8, 2021

Advances in Drug Delivery (Session #ADT08), with a discussion on the advances and innovations fueling the development of the next generation of antibody drug conjugates. Data identifying a novel immunosuppressive myeloid gene signature for clinical biomarker development.

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DNA Medicine Genome Genomics 52

Drug Discovery World

AUGUST 3, 2022

3 positive human cells and silence the targeted genes. Originally, GLP1R was viewed as unsuitable for selective drug delivery, due to its low abundance and restricted ability to internalise a large amount of drug conjugate. Plus, in numerous in vitro experiments, the conjugate has been able to specifically enter ?v?3

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Bioavailability In-Vivo RNA In-Vitro 52

The Pharma Data

JUNE 26, 2021

Through our innovation in the scientific discovery of new potential drug targets, personalised healthcare, molecular engineering, biomarkers and continuous drug delivery, we strive to design the right therapies for the right patients.

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Drug Delivery Clinical Trials Clinical Trials Medicine 52

Drug Discovery World

JANUARY 17, 2024

The company aims to advance platform technologies including chemoproteomics, molecular glue and covalent drug discovery, high-throughput screening, protein and antibody engineering, gene and epigenetic editing, gene and cell therapies, drug delivery, and data science.

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Drugs Drug Delivery Life Science Gene 52

Delveinsight

FEBRUARY 14, 2021

The health regulatory agencies all over have issued several guidelines, released strategies, and amended regulations to expedite the drug delivery process in the rare disease market landscape.

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Marketing Clinical Trials Clinical Trials Trials 52