Drug Discovery World

OCTOBER 6, 2023

In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of genetics, genomics and gene editing in drug discovery.

Drugs 52

Drugs Gene Editing Genome Genomics 52

Drug Discovery World

JULY 10, 2023

Its convergence with genomics makes sense and we have now multiple examples of AI being used to inform prescribing, diagnostics and drug discovery/ development. The team utilised genomic data from a database consisting of over 11,000 patients and which represented 33 types of human cancers. Disappointing, but work is continuing.

Gene Therapy 52

Gene Therapy Gene Scientist Gene Editing 52

Drug Discovery World

DECEMBER 12, 2022

Other research updates include a study by NIH 5 researchers using post-mortem brain tissues to understand genomic differences in individuals with attention deficit hyperactivity disorder. The study advances our understanding of ADHD by showing how the condition is tied to changes in how certain genes are expressed in the brain.

Drugs 52

Drugs Gene Editing Genome Genomics 52

Drug Discovery World

FEBRUARY 29, 2024

They are called: Sitting down with… PharmEnable , Is single-cell gene expression the next trend in next generation sequencing? In the second article, we hear from Dr Dina Finan, PhD, Product Manager at 10x Genomics and Dr Nick Downey, PhD, NGS Collaborations Lead at Integrated DNA Technologies.

Gene Expression 52

Gene Expression DNA Genome Genomics 52

XTalks

AUGUST 12, 2020

Xtalks spoke to lead author on the study, Mohamed Abdel-Mohsen, PhD, assistant professor, Vaccine & Immunotherapy Center at the Wistar Institute, about the emerging utility of identifying glycomic, or sugar, signatures on the surface of immune cells to help in their identification and potential targeting.

RNA 52

RNA Protein DNA In-Vivo 52

Drug Discovery World

APRIL 30, 2024

The biggest growth driver for mRNA therapeutics came from the Covid-19 pandemic, when mRNA-based vaccines proved effective in treating SARS-CoV-2, and pharmaceutical companies such as Pfizer/BioNTech and Moderna were successful in bringing these treatments to market. mRNA is a molecule made up of a single strand of ribonucleic acid (RNA).

RNA 52

RNA Protein Vaccination Vaccine 52

Delveinsight

JULY 30, 2020

‘Genome-tuning’ biotech Omega Therapeutics snags USD 85 Million. It will push a pipeline of treatments toward the clinic as well as bankroll the recognition of new targets for genomic medicines. Omega’s platform is designed to adjust gene expression to healthy levels rather than switching genes on and off.

Genome 52

Genome Genomics Antibody Gene 52