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Is single-cell gene expression the next trend in next generation sequencing? 

Drug Discovery World

By Dr Dina Finan, PhD, Product Manager at 10x Genomics and Dr Nick Downey, PhD, NGS Collaborations Lead at Integrated DNA Technologies. The post Is single-cell gene expression the next trend in next generation sequencing? To read this content in full, you need to login. Not yet a DDW member? Username or E-mail. Remember Me.

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10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit

BioTech 365

10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit 10x Genomics Puts Single Cell Analysis Within Reach of All With Low Throughput Gene Expression Kit Along with recent release of CellPlex, product increases … Continue reading →

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Gene expression delivery tool ‘slides’ instructions into cells

Drug Discovery World

Two methods currently used to deliver protein-making packages into cells, ‘mini promoters’ and serotype-mediated gene expression, vary widely. We wanted to develop a gene expression delivery tool that’s broadly useful in both preclinical and clinical models,” said Blackshaw. . in their effectiveness. “We

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Nucleome raises £37.5m to shine light on ‘dark genome’

pharmaphorum

million ($40 million) first-round financing that will be used to explore so-called ‘dark’ regions of the human genome. Nucleome’s platform adds 3D genomic information to a wealth of available genomic data, uncovering a new dimension of information that is disease as well as cell type-specific.

Genome 59
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Tune Therapeutics Debuts with $40 Million to Fine-Tune the Human Genome

BioSpace

Tune claims TEMPO can rapidly target and adjust the epigenomic machinery, controlling gene expression and dictating how the DNA will be molded.

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Novel artificial genomic DNA can replicate and evolve outside the cell

Scienmag

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

DNA 96
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CRISPR screening at scale: Achieving 1M cell data sets with an instrument-free, cost-effective approach

Drug Discovery World

Pooled CRISPR screens offer the ability to knock out or perturb many genes in a single experiment from several hundred to tens of thousands of targets in parallel. Genome-wide screens are becoming the standard for drug discovery to power unbiased identification of drug targets across gene regulatory networks.

Genome 52