The Genomic Medicine Revolution: Multi-Modality Approaches in Advanced Therapies
Pharmaceutical Technology
AUGUST 16, 2024
Genomic medicines offer new techniques for treating conditions once thought to be intractable - a world of opportunity awaits.
Genome Related Topics 
Tome Biosciences debuts with $213M and a new way to edit the genome
Bio Pharma Dive
DECEMBER 12, 2023
Based on the work of MIT scientists, the well-funded startup is developing ways to insert large sizes of genetic material anywhere in the genome without damaging or breaking DNA.
Genomics 
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AstraZeneca, seeking new drug targets, taps a genomics biotech and its AI technology
Bio Pharma Dive
SEPTEMBER 8, 2023
Worth up to $840 million, the collaboration will give Alexion access to Verge Genomics’ platform, which uses human tissue data to find drug targets for diseases that degrade the nerve system.
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Tome acquires startup Replace, gaining new genome editing tools
Bio Pharma Dive
JANUARY 2, 2024
The deal is the second startup sale engineered by University of California, Berkeley scientist Shakked Halperin, and gives Tome a way to insert or delete small DNA sequences into the genome.
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The new genomic frontier: Next-generation data management takes flight
pharmaphorum
JUNE 21, 2024
Explore the latest advancements in genomics and sequencing technologies, and learn how next-generation data management tools are transforming genomic research and applications in this new genomic frontier.
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Analyze whole genome sequencing samples at the speed of light
Bio Pharma Dive
FEBRUARY 13, 2023
Deliver fast and reliable results at low cost with a tool for whole genome analysis in just minutes
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Data-driven disease research harnessing the genome
pharmaphorum
JANUARY 9, 2024
Discover how the UK Biobank is leveraging technology and the power of genomics in data-driven disease research. Join the digital revolution in understanding and combating diseases using cutting-edge techniques and large-scale genomic data analysis.
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Working for a mature form of genomic medicines
pharmaphorum
MAY 29, 2024
In a new episode of the pharmaphorum podcast, Rahul Kakkar, CEO of gene editing company Tome, speaks with web editor Nicole Raleigh about programmable genomic integration (PGI) technology.
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AstraZeneca and Cancer Research Horizons extend genomics partnership
Drug Discovery World
SEPTEMBER 4, 2024
Cancer Research Horizons and AstraZeneca have signed a five-year renewal of the Functional Genomics Centre, a facility dedicated to advancing drug discovery with genome-altering technologies such as CRISPR. It helps us tap into previously unknown biology and advances our understanding of cancer resistance mechanisms.
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Hopewell Therapeutics raises funds for genomic medicines development
Pharmaceutical Technology
JUNE 8, 2023
Biotechnology company Hopewell Therapeutics has raised $25m in seed financing to accelerate the development of next-generation lipid nanoparticles for targeted delivery of genomic medicines. Hopewell Therapeutics is engaged in discovering, synthesising and developing advanced ttLNPs to provide next-generation genomic medicines.
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Short reads, big impact: How genomics is revolutionising cancer research
pharmaphorum
MAY 30, 2024
Discover how genomics is transforming cancer research through the study of DNA, RNA, and ctDNA. Learn about the latest breakthroughs in the field in this insightful short read.
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Lilly and HAYA collaborate to find genome targets for obesity
Drug Discovery World
SEPTEMBER 6, 2024
Eli Lilly and biotechnology company HAYA Therapeutics have announced a multi-year agreement to apply HAYA’s RNA-guided regulatory genome platform to support preclinical drug discovery efforts in obesity and related metabolic conditions. The company’s lead therapeutic candidate is HTX-001, in development for the treatment of heart failure.
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How 3D genomics can accelerate personalised medicine
Drug Discovery World
JULY 23, 2024
Dr Daniel Turner, Chief Scientific Officer, Enhanc3D Genomics, outlines how 3D genomics offers a radically novel approach to address challenges in drug target discovery and how it can affect change in drug target identification, cell therapy and personalised medicine.
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ERS Genomics and MDC sign CRISPR/Cas9 license agreement
Drug Discovery World
SEPTEMBER 5, 2024
ERS Genomics and not-for-profit Medicines Discovery Catapult (MDC) have signed a non-exclusive commercial-use CRISPR license agreement. This agreement with ERS Genomics offers huge potential for entrepreneurial scientists. John Milad, CEO, ERS Genomics, added: “We welcome MDC to our family of licensees.
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UK study backs whole-genome screening for cancer care
pharmaphorum
JANUARY 10, 2024
UK study led by Genomics England drawing on 100,000 Genomes Project and real-world clinical data backs use of whole-genome sequencing in cancer care
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Royal Marsden launches first UK genome testing facility to improve testing for cancer
Pharma Times
JUNE 14, 2024
The installation will double the capacity of cancer genomic testing using robotic automation
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Genome Edited Foods: Understanding the New FDA Guidance
XTalks
MARCH 1, 2024
In a pivotal move for the food industry, the US Food and Drug Administration (FDA) has unveiled industry guidance for genome edited foods derived from plants. This landmark guidance aims to demystify the FDA’s risk-based approach towards both genome edited foods and all new plant varieties. What is Genome Editing?
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‘100 Million Cell Challenge’ to boost single cell genomics research
Drug Discovery World
AUGUST 15, 2024
Scale Biosciences (Scale Bio) has launched the ‘100 Million Cell Challenge’, which hopes to push the boundaries of single-cell genomics research, in collaboration with Ultima Genomics and NVIDIA. Researchers interested in participating can submit their project proposals from 8 August to 15 October 2024.
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A new dawn of the genomic age: five areas set to be transformed in 2023
pharmaphorum
JANUARY 26, 2023
2022 was a banner year for genomics. In March, the collaborative T2T consortium published the first complete telomere-to-telomere sequence of the human genome, filling in the last 8% of the 3 billion base pairs that make up our DNA.
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Investment fuels AI-driven development of breakthrough genomic medicines
pharmaphorum
OCTOBER 12, 2022
David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. We founded Whitelab Genomics after realising the potential to use data, data science, and AI in a more systematic way to develop genomic therapies,” Del Bourgo says.
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Genome Research publishes a special issue in Single-cell Genomics
Scienmag
OCTOBER 1, 2021
October 1, 2021 – Genome Research ([link] publishes a special issue highlighting novel advances and insights in Single-cell Genomics. October 1, 2021 – Genome Research ([link] publishes a special issue highlighting novel advances and insights in Single-cell Genomics. Credit: Cover artwork © Victor O.
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UK Biobank releases largest-ever genome sequencing dataset
pharmaphorum
NOVEMBER 30, 2023
UK Biobank releases largest-ever genome sequencing dataset Phil.Taylor Thu, 30/11/2023 - 10:00 Bookmark this
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Experts prefer whole genome sequencing as viable option to identify & characterize bacteria as concerns of AMR escalate
AuroBlog - Aurous Healthcare Clinical Trials blog
DECEMBER 18, 2023
As antimicrobial resistance (AMR) poses a growing threat to global public health, challenging the effectiveness of antibiotics and other antimicrobial drugs, medical experts suggest whole genome sequencing as a viable option to identify and characterize the bacteria, viruses, fungi or parasites, along with their transmission pattern.
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Magazine: Genomic projects exploit scale as clinical applications play catch-up
Pharmaceutical Technology
JULY 26, 2022
The last few months have marked the publication of research emerging from projects designed to collect and analyse genomic data on a wider scale than was previously thought possible. The post Magazine: Genomic projects exploit scale as clinical applications play catch-up appeared first on Pharmaceutical Technology.
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Uncovering packaging impurities with rAAV genome sequencing
Drug Discovery World
MAY 1, 2024
Join DDW for this exclusive free event, ‘ rAAV genome sequencing with Oxford Nanopore uncovers transgene integrity and packaging impurities ’. The post Uncovering packaging impurities with rAAV genome sequencing appeared first on Drug Discovery World (DDW). The event will be supported by Oxford Nanopore Technologies.
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How rAAV genome sequencing uncovers transgene integrity
Drug Discovery World
APRIL 24, 2024
Join DDW for this exclusive free event, ‘ rAAV genome sequencing with Oxford Nanopore uncovers transgene integrity and packaging impurities ’. The post How rAAV genome sequencing uncovers transgene integrity appeared first on Drug Discovery World (DDW). The event will be supported by Oxford Nanopore Technologies.
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Genomics England will move HQ to Canary Wharf’s new biocluster
pharmaphorum
JUNE 13, 2022
Canary Wharf’s bid to become a new hub for the life sciences sector in the UK has been given a boost following the decision by Genomics England to relocate to the development. Genomics England will move into space at the iconic One Canada Square skyscraper (pictured) that was the EMA’s home before the move to the Netherlands.
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Emmes and MedGenome Launch Genomics Strategic Partnership Focused on Advancing Rare Disease Research
Pharma Mirror
NOVEMBER 16, 2021
Rockville, Emmes, a global, full-service Clinical Research Organization dedicated to supporting the advancement of public health and biopharmaceutical innovation, today announced a partnership with MedGenome aimed at accelerating breakthrough treatments, powered by human genomics, for rare disease patients.
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STAT+: ??Genomics is racing toward a $100 genome. Are we ready for it?
STAT News
JULY 27, 2022
As the cost of DNA sequencing plummets, we’re fast approaching a point when decoding a human genome could cost $100 — about as much as the average American’s weekly grocery store run. Health systems are preparing to test programs that could lead to the use of whole-genome screening in millions of newborns.
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Why genomic healthcare data matters in the development of new therapies
Drug Discovery World
NOVEMBER 7, 2022
Genomic healthcare data is critical to identify disease risk, ancestry, traits and response to medicines and aids in the development of new targeted therapies – precision medicines. In April 2003, after its launch in October 1990, the project was completed, generating the first sequence of the human genome. The origins .
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How Hazel Jones is charting new horizons in genomics
BioPharma Reporter
MAY 15, 2024
Hazel Jones is the interim CEO and chief operations officer at Enhanc3D Genomics. We sat down with her to discuss her leap of faith into 3D genomics, and how she is scaling the business and driving operational change.
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Kansas children’s hospital first to use world’s most advanced genomic sequencing
BioPharma Reporter
OCTOBER 10, 2023
Childrenâs Mercy Kansas City, an independent pediatric health organization, has become the first health care system to replace old genetic tests, such as rapid exome and chromosomal microarray analysis, with the worldâs most-advanced genomic sequencing technology from PacBio.
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GEN-001 by Genome & Co for Head And Neck Squamous Cell Carcinoma (HNSC): Likelihood of Approval
Pharmaceutical Technology
DECEMBER 4, 2023
GEN-001 is under clinical development by Genome & Co and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC).
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Congenica extends contract with Hong Kong Genome Project
BioPharma Reporter
OCTOBER 9, 2023
Congenica, a digital health company providing software and solutions for the analysis and interpretation of genomic data at scale, has announced a two-year extension to its contract for the Hong Kong Genome Project (HKGP), the first large-scale genome sequencing initiative in Hong Kong.
The future, now: Revolutionising disease prevention through predictive genomics
pharmaphorum
JUNE 30, 2023
The future, now: Revolutionising disease prevention through predictive genomics Mike.Hammerton Fri, 30/06/2023 - 08:00 Bookmark this
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rAAV Genome sequencing uncovers transgene integrity and packaging impurities
Drug Discovery World
APRIL 16, 2024
The post rAAV Genome sequencing uncovers transgene integrity and packaging impurities appeared first on Drug Discovery World (DDW). A live Q&A session follows the webinar presentation.
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Large European study underlines power of genomic sequencing to diagnose diseases
STAT News
APRIL 12, 2023
LONDON — Using genome sequencing greatly expanded the number of diagnoses researchers could provide for children with developmental disorders from thousands of families across the United Kingdom and Ireland, researchers reported in a new study Wednesday. Read the rest…
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What are the key trends in genomics and precision medicine for 2024?
Drug Discovery World
JANUARY 29, 2024
Leading experts in genomics, personalised medicine and drug discovery convened at the Precision Medicine Community Event in London to unveil the latest advancements shaping the future of healthcare. The post What are the key trends in genomics and precision medicine for 2024? appeared first on Drug Discovery World (DDW).
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USDA-ARS releases genome of the voracious desert locust
Scienmag
JUNE 26, 2022
June 27, 2022–The first high-quality genome of the desert locust—those voracious feeders of plague and devastation infamy and the most destructive migratory insect in the world—has been produced by U.S. June 27, 2022–The first high-quality genome of the desert locust—those voracious feeders of […].
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Oncotype DX: Breast cancer, genomics, and rethinking the oncology paradigm
pharmaphorum
JULY 27, 2023
Oncotype DX: Breast cancer, genomics, and rethinking the oncology paradigm Mike.Hammerton Thu, 27/07/2023 - 08:00 Bookmark this
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Novel technique opens up new possibilities in synthetic genomics
Drug Discovery World
DECEMBER 29, 2023
Known as ‘CReATiNG’ (Cloning Reprogramming and Assembling Tiled Natural Genomic DNA), the method offers a simpler and more cost-effective approach to constructing synthetic chromosomes. The thing about most synthetic genomics research is that it involves building chromosomes or genomes from scratch using chemically synthesised DNA pieces.
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UK announces mass genome sequencing programme for newborns
Medical Xpress
DECEMBER 13, 2022
UK health authorities on Tuesday announced a pioneering research programme using the genomes of 100,000 new-born babies, to detect rare genetic illnesses and speed up treatment.
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Gaps in breast cancer care in Europe and the importance of genomic testing
pharmaphorum
JUNE 23, 2023
Gaps in breast cancer care in Europe and the importance of genomic testing Mike.Hammerton Fri, 23/06/2023 - 08:00 Bookmark this
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Scientists sequence Beethoven's genome for clues into his painful past
NPR Health - Shots
MARCH 22, 2023
Scientists have sequenced the genome of Ludwig van Beethoven from two-century-old locks of hair, and found clues about the ailments that plagued him in life. Image credit: Henry Guttmann Collection/Getty Images)
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