XTalks

NOVEMBER 26, 2020

In addition to innovative new antibody drugs and mRNA vaccines, researchers have found that the sleep-regulating hormone melatonin may also offer protection against COVID-19. This reduced likelihood was increased to 52 percent when looking at African-Americans in the registry, adjusting for the same variables.

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XTalks

DECEMBER 22, 2021

If the past year is anything to go by, then 2022 will also be a year marked by continued innovations in the life sciences. Here is a look at some life science trends to expect in the coming year, including key themes and topics in the pharmaceutical, biotechnology and medical device industries to keep an eye out for in 2022.

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Drug Discovery World

JANUARY 9, 2024

Mike Ward, Global Head of Thought Leadership, Life Sciences and Healthcare, Clarivate said: “The fundamentals underpinning the biopharma sector have never been stronger, with new technologies fuelling medical advancements and providing treatment options to patients with previously unmet needs. The 2024 Drugs to Watch, are: 1.

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XTalks

NOVEMBER 10, 2021

The results were also published in the New England Journal of Medicine at the same time. Darbepoetin alfa is a synthetic version of the hormone erythropoietin, which is made in the kidneys and stimulates the production of red blood cells (RBC), or erythrocytes. percent for daprodustat and 10.5 percent for darbepoetin alfa.

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XTalks

NOVEMBER 15, 2021

Now, new research shows that the brain hormone serotonin may cause gut inflammation that could trigger flare-ups in Crohn’s disease. Waliul Khan, senior author on the study and professor of pathology and molecular medicine at McMaster University, said in an interview with Medical News Today.

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XTalks

FEBRUARY 14, 2024

The extensive research in developing more effective and less toxic treatments, such as targeted therapies, immunotherapies and precision medicine , has helped to considerably improve the survival rates for many types of childhood cancers.

Hormones 52

Hormones Development Genetics Life Science 52

XTalks

FEBRUARY 6, 2023

Erythropoietin is a hormone that is produced by the kidneys and signals the body to make red blood cells. Clinical Trial Outcomes The FDA approval of Jesduvroq is based on results from the Phase III ASCEND-D trial , which were published in the New England Journal of Medicine. How Does Jesduvroq ( daprodustat) Work?

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pharmaphorum

JUNE 7, 2022

Exact Sciences is pioneering diagnostics that enable personalised medicine for cancer patients. However, from diagnostics to the cutting-edge medicines and approaches to treat each person’s tumour type individually, a vast health inequity sadly exists across the globe.

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XTalks

MARCH 8, 2024

Risk factors include aging, hormonal changes, low body weight, low calcium intake and use of certain medications. I am proud that Sandoz continues to pioneer access to these life-changing medicines for the patients who need them most,” said Keren Haruvi, president, Sandoz North America, in a statement from the company.

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XTalks

FEBRUARY 3, 2023

Current treatments include hormonal therapies that focus on blocking the function of the estrogen receptor, curbing its production or degrading the receptor itself. Future Steps with elacestrant The European Medicines Agency (EMA) has accepted and is currently reviewing the Marketing Authorization Application (MAA) for elacestrant.

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Clinical Trials Clinical Trials FDA Approval Trials 97

XTalks

JUNE 16, 2023

Notably, the EMPA-KIDNEY Phase III clinical trial results published in The New England Journal of Medicine revealed that Jardiance (empagliflozin), an SGLT2 inhibitor, significantly reduced the risk of kidney disease progression or death from cardiovascular causes compared to placebo in patients with pre-existing CKD.

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XTalks

MARCH 25, 2024

They work by mimicking the action of the naturally occurring hormone GLP-1, which is involved in regulating blood sugar and appetite. Medicines have side effects, but the important part is that they’re mild to moderate in the research studies,” said Velazquez. Oprah asked why coverage of weight loss drugs is still limited.

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XTalks

AUGUST 15, 2023

Akeega is a dual-action tablet (DAT) that contains the company’s androgen receptor-targeting hormone therapy Zytiga (abiraterone acetate) and PARP inhibitor (poly [ADP-ribose] polymerase inhibitor) niraparib. Niraparib is also sold by GSK under the name Zejula in other indications.

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XTalks

FEBRUARY 9, 2021

A report published in the New England Journal of Medicine (NEJM) in August 2020 — followed by several more studies, including one in Diabetes, Obesity and Metabolism in November — reported on the observed link. Experts are unclear as to why the phenomenon is occurring among some patients.

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Insulin Immune Response Hormones Research 105

Roots Analysis

JANUARY 23, 2024

They also play important roles in antibiotics , toxins, hormones, and enzymes. These versatile molecules serve various diverse roles, functioning as neurotransmitters, growth factors, ion channel ligands, hormones, anti-infectives, and more. When introduced into the body, lab-synthesized peptides become active.

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The Pharma Data

FEBRUARY 21, 2022

Tackling this challenge with advanced technologies and products, radiology is a key enabler to transform healthcare, expanding personalized medicine and improving outcomes for patients. Every year 47 million women enter menopause, a period where women are at the peak of their life’s activity, personally and professionally.

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XTalks

NOVEMBER 9, 2023

XTALKS WEBINAR: The Evolution of the Cardiovascular Clinical Development Landscape and Potential Role of GLP-1 RAs Live and On-Demand: Wednesday, December 6, 2023, at 11am EST (4pm GMT/UK) Register for this free webinar to learn about successful study outcomes in developing GLP1s to new therapeutic areas within cardiovascular medicine and more.

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XTalks

JUNE 27, 2022

These types of treatments represent the goal of precision medicine , where therapies are tailored to specific patient types. Tafinlar/Mekinist are considered targeted cancer therapies, meaning that they can be used to treat cancer types with a certain molecular signature.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Regulation 52

pharmaphorum

DECEMBER 23, 2020

It has been a year dominated by the pandemic and many life sciences research projects were put on hold as big pharma turned its attention to vaccines and therapies. But there was some considerable progress in other fields of medicine even though research efforts were diverted away, reports Richard Staines.

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The Pharma Data

APRIL 11, 2023

The company has the passion and determination to develop innovative medicines that help improve and extend the lives of people living with cancer. About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition.

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The Pharma Data

DECEMBER 9, 2020

The new company, created by Hillhouse Capital Venture Partners, launched this week with a mission to pursue the most promising advances in medicine for underserved patients in Asia and around the world. The creation of Overland isn’t the only exciting thing happening for international life sciences companies and organizations.

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XTalks

FEBRUARY 5, 2024

In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. The top 40 best-selling oncology drugs in 2023, informed by 2022 sales statistics, mark significant milestones in cancer treatment and research.

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XTalks

MAY 17, 2023

. “Today’s approval of fezolinetant is a significant and long-awaited milestone for individuals in the US who experience moderate to severe vasomotor symptoms during the menopausal transition,” said Genevieve Neal-Perry, MD, PhD, Chair of the UNC School of Medicine Department of Obstetrics and Gynecology, in Astellas’ news release.

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Hormones FDA Approval Drugs Clinical Trials 95

XTalks

MARCH 1, 2021

And while conventional dry eye can have a number of causes — including blepharitis, hormone-related changes in post-menopausal women and contact lens use — mask-associated dry eye is largely cropping up in people who wear face masks for extended periods during the day.

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pharmaphorum

JUNE 8, 2022

The UK medicines regulator has awarded Alnylam’s RNAi-based therapy zilebesiran for hypertension an ‘innovation passport ‘, a designation designed to speed up NHS access to promising new medicines. The study is enrolling adults whose blood pressure is not adequately controlled by standard medicines.

Gene Silencing 52

Gene Silencing Drugs Medicine Regulation 52

XTalks

FEBRUARY 5, 2024

In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. The top 40 best-selling oncology drugs in 2023, informed by 2022 sales statistics, mark significant milestones in cancer treatment and research.

FDA Approval 52

FDA Approval Drugs Sales Development 52

XTalks

FEBRUARY 7, 2023

Current treatments for HR+ breast cancer patients include hormonal therapies, chemotherapies for those that do not respond to hormonal therapy alone and targeted therapies, either stand-alone or in combination with hormonal therapies. What does this Approval Mean for Breast Cancer Patients?

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XTalks

AUGUST 2, 2023

With each passing year, pharmaceutical companies around the globe strive to deliver cutting-edge medicines, therapies and vaccines that impact the lives of millions. In this in-depth article, we embark on a captivating journey to uncover the top 30 pharma and biotech companies that have been instrumental in shaping the future of medicine.

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XTalks

NOVEMBER 20, 2023

AstraZeneca has won its first-in-class approval for its AKT inhibitor Truqap (capivasertib) in combination with Faslodex (fulvestrant) for treating patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer.

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XTalks

AUGUST 10, 2022

Approximately 80 to 85 percent of these cases were previously considered to be the HER2-negative subtype (which includes hormone receptor positive and triple negative breast cancer), which means the tumors do not make higher than normal amounts of the HER2 protein.

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FDA Approval HR Hormones Antibody 98

XTalks

APRIL 29, 2022

Tirzepatide is a novel investigational obesity treatment that contains mimetics of two hormones that are involved in regulating appetite in a single peptide: a GIP (glucose-dependent insulinotropic polypeptide) receptor agonist and a GLP-1 (glucagon-like peptide-1) receptor agonist. percent and 22.5 percent, respectively, compared to placebo.

Trials 98

Trials Drugs FDA Approval Clinical Trials 98

XTalks

NOVEMBER 19, 2021

Natriuretic peptides like N-terminal (NT)-pro hormone B type natriuretic peptide (NT-proBNP), or BNP, are routinely used for acute and chronic heart failure. For safety endpoints, cardiac troponin — either high sensitivity or standard — are used as markers for safety and myocardial injury and toxicity.

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Drug Discovery World

OCTOBER 14, 2022

HTS is widely used by pharmaceutical companies to identify compounds (or ‘hits’) that show pharmacological activity, which are used as starting points to optimise medicines during the drug discovery process. HTS as a tool for drug discovery has evolved rapidly since the origin of the technique in the 1990s. The future of HTS . Elsen and J.D.

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pharmaphorum

MARCH 5, 2021

Fundamental metabolic and hormonal differences can make women difficult to study compared to men but that is exactly why we must ensure we’re studying them.”. A cautious approach to involving women has not been without good reason. Representation of diverse ethnic groups is also low, says Maini. Levelling the field through technology.

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Pharmaceutical Technology

JANUARY 22, 2023

In 2022, the FDA approved only 37 new medicines, an underwhelming number compared to 98 in 2018. The mutation leads to disordered thyroid hormone transport, which causes patients to experience intellectual and motor disabilities. T3 is a major hormone in the blood that regulates thyroid levels.

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XTalks

MAY 20, 2022

Life science industry data analytics company Evaluate Vantage predicts that Mounjaro could bring in $4.9 And that is a big win for Lilly as it looks to take on diabetes drug rival Novo Nordisk, which currently dominates the market with its diabetes injection Ozempic (semaglutide). billion in sales for Lilly by 2026.

Insulin 52

Insulin Life Science Drugs Sales 52

Pharmaceutical Technology

APRIL 24, 2023

. “Biologics products may contain proteins that control the action of other proteins and cellular processes, genes that control production of vital proteins, modified human hormones, or cells that produce substances that suppress or activate components of the immune system.

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