The Pharma Data

MARCH 20, 2023

We are therefore delighted that patients in China will now have a new treatment option for metastatic hormone-sensitive prostate cancer that delays disease progression, extends survival and maintains quality of life”, said Christine Roth, Member of the Executive Committee of Bayer’s Pharmaceuticals Division and Head of the Oncology SBU at Bayer.

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Hormones Trials Sales Development 40

The Pharma Data

MARCH 23, 2023

The new Phase III clinical study, ARASTEP, will investigate the efficacy of darolutamide plus androgen deprivation therapy (ADT) versus ADT alone in hormone-sensitive prostate cancer, in patients with high-risk biochemical recurrence (BCR) who have no evidence of metastatic disease by conventional imaging and a positive PSMA PET/CT at baseline.

Hormones 40

Hormones Trials Branding Development 40

XTalks

MARCH 13, 2024

Related: Transforming Eye Care: Innovating New Glaucoma and Dry Eye Disease Treatments — Featuring Pierre Simon, VP Marketing, Sight Sciences – Xtalks Life Science Podcast Ep. Hormone-based therapeutics aim to delay glaucoma progression by enhancing estrogen’s potential protective effects.

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Gene Therapy Gene Life Science DNA 111

XTalks

DECEMBER 22, 2021

If the past year is anything to go by, then 2022 will also be a year marked by continued innovations in the life sciences. Here is a look at some life science trends to expect in the coming year, including key themes and topics in the pharmaceutical, biotechnology and medical device industries to keep an eye out for in 2022.

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XTalks

NOVEMBER 26, 2020

In addition to innovative new antibody drugs and mRNA vaccines, researchers have found that the sleep-regulating hormone melatonin may also offer protection against COVID-19. The results still require further validation, including experimental and clinical evaluation.

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Research Hormones Protein Regulation 98

The Pharma Data

MARCH 31, 2022

The company’s Supply Center in Berlin will be transformed into a Center of Excellence for parenterals, and the Supply Center in Leverkusen into a Center of Excellence for non-hormonal solids. The Supply Center Bergkamen will become a Center of Excellence for contrast media and hormone products while expanding capacities for therapeutics.

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XTalks

NOVEMBER 15, 2021

Now, new research shows that the brain hormone serotonin may cause gut inflammation that could trigger flare-ups in Crohn’s disease. Growing evidence continues to show fundamental links between the nervous system and the gut microbiome.

Hormones 98

Hormones Regulation Research Production 98

XTalks

NOVEMBER 10, 2021

Darbepoetin alfa is a synthetic version of the hormone erythropoietin, which is made in the kidneys and stimulates the production of red blood cells (RBC), or erythrocytes. Kidney dysfunction in CKD leads to impaired production of the hormone, particularly in more advanced disease.

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Trials Hormones Drugs FDA Approval 97

XTalks

MARCH 6, 2023

Some of the higher-value approved products include contraceptives, such as hormonal vaginal rings and birth control pills. The portfolio contains approximately forty-five commercial products, four products in the pipeline, and forty approved non-marketed products, many of which are generics focused on women’s health.

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Production Branding Dermatology Hormones 98

pharmaphorum

FEBRUARY 3, 2022

Oliver Stohlmann’s Corporate Survival Hacks series draws on his experiences of working in local, regional and global life science communications to offer some little tips for enjoying a big business career. This post looks at dealing with sudden stress and turning it into positive energy. Visualise success. About the author.

Life Science 98

Life Science Hormones Sales Marketing 98

XTalks

JUNE 5, 2023

Semaglutide acts as a glucagon-like peptide-1 (GLP-1) receptor agonist, mimicking the GLP-1 hormone released in the gastrointestinal tract after eating. GLP-1 stimulates insulin production, thus reducing blood glucose levels, and it interacts with the brain to suppress appetite and create a feeling of fullness.

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XTalks

FEBRUARY 6, 2023

Erythropoietin is a hormone that is produced by the kidneys and signals the body to make red blood cells. Patients can consult with their healthcare providers to select the option that is most appropriate,” added Dr. Farrell. How Does Jesduvroq ( daprodustat) Work?

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XTalks

NOVEMBER 3, 2022

Mounjaro was approved this summer as a Type 2 diabetes treatment and is the first diabetes drug with dual action, targeting two hormones involved in insulin production and appetite (GIP and GLP-1). In contrast, Novo’s diabetes drugs Ozempic and Rybelsus (both semaglutide) are just GLP-1 agonists.

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Sales FDA Approval Production Insulin 98

XTalks

FEBRUARY 14, 2024

In fact, for healthcare providers and medical device companies, these advancements are both a challenge and an opportunity.

Hormones 52

Hormones Development Genetics Life Science 52

Drug Discovery World

JANUARY 9, 2024

Mike Ward, Global Head of Thought Leadership, Life Sciences and Healthcare, Clarivate said: “The fundamentals underpinning the biopharma sector have never been stronger, with new technologies fuelling medical advancements and providing treatment options to patients with previously unmet needs.

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Drugs Antibody Gene Editing Medicine 69

Roots Analysis

MARCH 21, 2022

Biologics have emerged as a direct consequence of the rapid development that has taken place in the field of life sciences, particularly in cell and molecular biology, over the past few decades. There are a variety of biologically derived therapeutics that are presently available / being developed.

Drug Delivery Systems 52

Drug Delivery Systems Drug Delivery Antibody Marketing 52

XTalks

JUNE 16, 2023

Additionally, Phase III trials for finerenone , an aldosterone hormone blocker thought to play a role in CKD, are ongoing for patients with kidney disease and type 2 diabetes. Montelukast, a pro-inflammatory lipid mediator antagonist, is also under investigation in a Phase III clinical trial as a potential therapy for diabetic kidney disease.

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Clinical Trials Clinical Trials Trials Hormones 96

Roots Analysis

JANUARY 23, 2024

They also play important roles in antibiotics , toxins, hormones, and enzymes. These versatile molecules serve various diverse roles, functioning as neurotransmitters, growth factors, ion channel ligands, hormones, anti-infectives, and more. When introduced into the body, lab-synthesized peptides become active.

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Drug Discovery World

APRIL 23, 2024

Oxeia Biopharma is developing OXE103 (ghrelin), a synthetic peptide hormone with pleiotropic activity including enhanced mitochondrial ATP production, reduction of oxidative damage, and increased long-term potentiation of axons. Neuronasal is studying N-acetyl cysteine, a known antioxidant which has shown promise in early trials of mild TBI.

Drugs 59

Drugs Development Life Science Hormones 59

XTalks

OCTOBER 11, 2023

They mimic the action of GLP-1, a hormone that helps regulate blood sugar levels by enhancing insulin secretion. Rybelsus is Novo’s third semaglutide product on the market, a tablet form of the drug used for the treatment of type 2 diabetes.

Drugs 59

Drugs Insulin Hormones FDA Approval 59

XTalks

MARCH 8, 2024

Risk factors include aging, hormonal changes, low body weight, low calcium intake and use of certain medications. It occurs when the formation of new bone doesn’t keep up with the loss of old bone. The disease often progresses without symptoms until a fracture happens, typically in the wrist, hip or spine.

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Drugs FDA Approval Production Immune Response 59

pharmaphorum

JUNE 7, 2022

Exact Sciences is pioneering diagnostics that enable personalised medicine for cancer patients. Steven joined Exact Sciences in April 2021 as Vice President Medical, International.

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Medicine Life Science Hormones Doctors 90

XTalks

FEBRUARY 9, 2021

He said, “Stressful conditions lead to elevated levels of regulatory hormones that raise blood sugar to aid the body in fighting whatever insult it’s facing, such as illness or injury. For people with underlying conditions, that can be enough to kick them over the edge.”.

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Insulin Immune Response Hormones Research 105

XTalks

FEBRUARY 19, 2021

Evofem Biosciences announced the launch of their new national campaign called, “Get Phexxi,” designed to raise awareness about the company’s non-hormonal birth control method. In May 2020, the US Food and Drug Administration (FDA) approved Phexxi , a non-hormonal contraceptive for women.

Hormones 88

Hormones Production FDA Approval Marketing 88

XTalks

MARCH 22, 2021

As a leader in life sciences, diagnostics and applied chemical markets, it is looking to grow its cancer diagnostics pipeline. Resolution has been a leader in the development of NGS-based companion diagnostics (CDx) test development and registration services for precision oncology.

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Life Science Development Marketing Gene Expression 110

XTalks

MARCH 29, 2021

They also believe caffeine could potentially disrupt fetal stress hormones, putting infants at risk for rapid weight gain after birth and for chronic conditions such as obesity, heart disease and diabetes later on in life.

Genotype 98

Genotype Allergies Hormones Research 98

pharmaphorum

NOVEMBER 27, 2022

Incidents such as the hormone replacement therapy drug shortage in early 2022 have shown the damaging impact supply chain issues can have on people who depend on these drugs. Neil Keegan is head of manufacturing at Automata, a London-based biotech company providing robotic automation solutions to the life sciences industry.

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Production Manufacturing Drugs Marketing 105

XTalks

AUGUST 15, 2023

Akeega is a dual-action tablet (DAT) that contains the company’s androgen receptor-targeting hormone therapy Zytiga (abiraterone acetate) and PARP inhibitor (poly [ADP-ribose] polymerase inhibitor) niraparib. Niraparib is also sold by GSK under the name Zejula in other indications.

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FDA Approval Gene Hormones Licensing 52

XTalks

FEBRUARY 21, 2024

Tirzepatide’s mechanism of action involves activating two naturally produced hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). MASH is known to occur in an estimated three to five percent of adults in the US.

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Clinical Trials Clinical Trials Trials Insulin 59

XTalks

JUNE 20, 2022

TTR is made in the liver and is involved in carrying the thyroid hormone thyroxine (T4) and retinol (vitamin A) to the liver. Defects in the TTR transporter leads to a buildup of amyloid protein (amyloidosis) in tissues and organs, occurring mainly in the nerves in the peripheral nervous system.

FDA Approval 98

FDA Approval Protein Genetics RNA 98

XTalks

FEBRUARY 3, 2023

Current treatments include hormonal therapies that focus on blocking the function of the estrogen receptor, curbing its production or degrading the receptor itself. Mutations in the ESR1 , however, have contributed to the rise of endocrine resistance.

Clinical Trials 97

Clinical Trials Clinical Trials FDA Approval Trials 97

XTalks

SEPTEMBER 17, 2020

Symptoms and Etiology: Caused by an overproduction of growth hormone, acromegaly primarily affects adults. By reducing the amount of growth hormone in the blood, progressive enlargement of bones should be slowed. By reducing the amount of growth hormone in the blood, progressive enlargement of bones should be slowed.

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Trials Gene Hormones Clinical Trials 98

XTalks

JULY 2, 2021

Currently, there is no scientific evidence to suggest that the vaccines induce any hormonal changes that would lead to irregular periods. This had led some to wonder whether period changes may be a potential side effect of the vaccines. Most physicians say there is nothing to worry about and that the changes are temporary.

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Vaccination Vaccine Protein Immune Response 105

XTalks

MARCH 25, 2024

They work by mimicking the action of the naturally occurring hormone GLP-1, which is involved in regulating blood sugar and appetite. GLP-1 receptor agonists, a class of drugs initially developed to treat type 2 diabetes, have been found to have significant effects on weight loss.

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XTalks

NOVEMBER 9, 2023

Zepbound contains mimetics of the GLP-1 and GIP hormones that regulate appetite and blood sugar. “In light of increasing rates of both obesity and overweight in the United States, today’s approval addresses an unmet medical need.”

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FDA Approval Manufacturing Drugs Pharmacy 59

The Pharma Data

FEBRUARY 21, 2022

Elinzanetant, a non-hormonal development compound, is currently being investigated in the Phase III clinical development program OASIS for the treatment of vasomotor symptoms during menopause. Every year 47 million women enter menopause, a period where women are at the peak of their life’s activity, personally and professionally.

Radiology 52

Radiology Cardiology Development Production 52

XTalks

FEBRUARY 8, 2024

Diabetes remains a critical global challenge, affecting millions of lives and commanding significant attention from the medical, life sciences and pharmaceutical sectors. Understanding the market dynamics of diabetes treatments becomes crucial for professionals across these industries.

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Sales Insulin FDA Approval Drugs 52