Pharmaceutical Technology

JULY 8, 2022

Xenetic Biosciences and Catalent Pharma Solutions have signed an agreement for the cGMP manufacturing of the Xenetic’s recombinant protein, Human DNase I. The over-production or lowered clearance of NETs can cause serious inflammatory and autoimmune pathologies and create pro-tumorigenic niches for cancer growth and metastasis.

Manufacturing 147

Manufacturing Protein Clinical Development Development 147

Drug Discovery World

FEBRUARY 14, 2024

Vaccination responses need to be rapid, efficacious and cost-effective if they are to outpace new viral threats emerging across the globe, says Jian He (Jason) , Chemistry, Manufacturing and Controls (CMC) Head, WuXi Vaccines. As a result of the pressures placed on the industry during the Covid-19 pandemic, timelines have already changed.

Protein 59

Protein Vaccination Vaccine Manufacturing 59

XTalks

SEPTEMBER 27, 2023

EQUII, a food tech startup renowned for its protein bread that focuses on high complete protein and low carbs, is expanding its product line. This new range, which debuted at Expo East last week, includes Plain and Multigrain protein bread, delivering consumers a blend of nutrition without compromising on flavor.

Protein 59

Protein Branding Containment Production 59

Drug Discovery World

JULY 24, 2023

The Defense Advanced Research Projects Agency (DARPA) has announced that Ginkgo Bioworks, which is building a platform for cell programming and biosecurity, has been awarded a four-year contract worth up to $18 million to reimagine how to manufacture complex therapeutic proteins.

Protein 52

Protein Manufacturing Gene Sequencing Production 52

Drug Discovery World

MAY 7, 2024

Where the bottlenecks of achieving higher cell density and higher titers were once thought to be issues of the past, hurdles have now shifted to achieving speed and scale in mAb production without sacrificing quality. DC: Antibodies have and remain a large product class within the biopharmaceutical market.

Antibody 59

Antibody Production Manufacturing Engineer 59

Scienmag

FEBRUARY 23, 2021

(February 23, 2021) – The Gates Biomanufacturing Facility (GBF) has completed the manufacturing and release of a protein-based biologic under Good Manufacturing Practice for Phase 1 Investigational Drugs for first-in-human clinical trials.

Protein 57

Protein Manufacturing Clinical Trials Clinical Trials 57

Pharmaceutical Technology

JULY 29, 2022

Pfizer (New York, New York) and Moderna’s (Cambridge, Massachusetts) Omicron-specific Covid-19 vaccines are in late-stage development, have demonstrated good efficacy against the variant and will likely be available to the public later this year to provide an additional booster and increase demand for injectable manufacturing.

Manufacturing 130

Manufacturing Vaccination Vaccine Packaging 130

FDA Law Blog

MARCH 5, 2024

Gaulkin & Riëtte van Laack — As readers of this blog know, there is a lot of contention about the naming of alternative protein products (APPs), including both plant-based and cell-cultured alternatives for (traditional) animal products. We’ve previously blogged about this ongoing battle here , here , here , and here.

Protein 59

Protein Production DNA Containment 59

BioPharma Reporter

JANUARY 24, 2023

CDMO AGC Biologics will produce Tzield (teplizumab-mzwv), a recently-approved T1D treatment from Provention Bio, at its Seattle protein biologics manufacturing site.

Production 98

Production Protein Manufacturing 98

BioTech 365

SEPTEMBER 9, 2020

PRESS RELEASE Biotest is one of the first plasma protein manufacturers to provide digital package leaflets for all products … Continue reading → DGAP-News: Biotest AG / Key word(s): Miscellaneous 10.09.2020 / 07:00 The issuer is solely responsible for the content of this announcement.

Packaging 40

Packaging Packaging Protein Manufacturing 40

pharmaphorum

MAY 10, 2021

BioNTech has said it plans to set up a regional base and new manufacturing site in Singapore so that the biotech can keep pace with demand for its mRNA-based coronavirus vaccine and pipeline products in other disease areas. The post BioNTech to set up mRNA manufacturing site in Singapore appeared first on.

Manufacturing 129

Manufacturing Vaccination Vaccine Protein 129

XTalks

MARCH 31, 2023

By growing high quality crystal structures of protein-based therapeutics under microgravity, researchers can gain better insights into their complex structures and stability. The proteins will be analyzed back on Earth using techniques such as X-ray diffraction and compared with crystals from the same biologics grown on Earth.

Protein 97

Protein Research Development Manufacturing 97

Roots Analysis

JANUARY 15, 2024

Although biopharmaceuticals offer significant profit margins and have demonstrated the potential to treat a myriad of disease indications, they are generally associated with high costs of development and complex manufacturing protocols. Advanced and complex technologies are required for manufacturing, as well as testing of biopharmaceuticals.

Contract Manufacturing 40

Contract Manufacturing Manufacturing Production Development 40

Drug Discovery World

AUGUST 8, 2023

Ginkgo Bioworks and Merck have collaborated to improve the production of biologics. “In particular, we will utilise some of our unique capabilities, such as automated protocols to do predictive ultra high-throughput multiplexed screening, product characterisation and process optimisation. .

Manufacturing 52

Manufacturing Clinical Supply Production Engineer 52

XTalks

OCTOBER 27, 2020

In recent years, food companies have created products that go beyond taste and convenience and also offer functionality and health benefits. One such fusion beverage is high-protein iced tea – a functional, refreshing beverage that has the potential to be the next big beverage trend. This is where iced tea comes in.

Protein 105

Protein Marketing Containment Manufacturing 105

XTalks

FEBRUARY 25, 2022

EverGrain Ingredients, a barley protein and fiber solutions company, recently received certification from the Upcycled Food Association (UFA) for its entire portfolio of products. The brand saw a unique opportunity to extract the excess barley to meet the global demand for sustainable, plant-based products. Barley Milk.

Production 98

Production Protein Branding Bioavailability 98

Drug Discovery World

FEBRUARY 12, 2024

million grant to engineer microbial cell factories to produce membrane proteins which will support future drug screening and sustainable chemical production. Membrane proteins are crucial molecules on the surface of cells with numerous biological functions, such as sensing hormones or cell communication.

Research 105

Research Drugs Engineer Protein 105

XTalks

NOVEMBER 23, 2021

Canadian pharma and biotech contract development and manufacturing organization (CDMO) Biovectra has announced plans for building one of the first state-of-the-art mRNA vaccine and biomanufacturing facilities in Canada. The investment will go towards expanding Biovectra’s existing production facility in Charlottetown, the capital of PEI.

Manufacturing 98

Manufacturing Vaccination Vaccine Drugs 98

Drug Discovery World

NOVEMBER 27, 2023

A complex journey Biotherapeutics discovery and development upstream encounters challenges in cell line development (CLD), clone screening and characterisation, scale up, and eventually production. Stable clonal cell banks are used for GMP production of the final drug product. Metab Eng 2020;57:203.

Production 59

Production Engineer Gene Editing Gene 59

Roots Analysis

AUGUST 8, 2023

Disposable bioreactors have transformed the process of conventional biomanufacturing, and their adoption is increasing rapidly for production of various biologics, such as antibody, recombinant proteins, cell and gene therapy. As a result, the products are also removed continuously. What is Single-use Bioreactors?

Manufacturing 52

Manufacturing Production Marketing Gene Therapy 52

Pharmaceutical Technology

DECEMBER 7, 2022

BioPIPS plans to utilise research and innovation to enhance the biologics manufacturing expertise of Singapore, which comprises recombinant therapeutic proteins and vaccines. Additionally, BioPIPS intends to equip the country’s biologics production expertise for launching new products and manufacturing technologies.

Scientist 130

Scientist Manufacturing Vaccination Vaccine 130

Roots Analysis

MARCH 9, 2022

In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines, and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical products are currently under clinical investigation worldwide. . Capacity Analysis.

Manufacturing 52

Manufacturing Marketing Contract Manufacturing Protein 52

Pharmaceutical Technology

JUNE 29, 2022

For hundreds of years, we have found myriad uses for microbial enzymes in manufacturing – from food, drink, and household products to a range of industrial applications. The enzymes must be manufactured under cGMP conditions – completely free of animal-derived ingredients.”. Developing best-in-class speciality enzymes.

Drugs 295

Drugs Gene Therapy Manufacturing Production 295

Drug Discovery World

JANUARY 26, 2024

Researchers from Tokyo University of Science (TUS) have found a simple, low-cost way to optimise the production of monoclonal antibodies (mAbs) and reduce manufacturing costs. What’s more, IgG production decreased by approximately 30% in DFMO-treated cells.

Antibody 102

Antibody Research Protein Production 102

Roots Analysis

MARCH 2, 2022

Orally administrable protein / peptide-based therapeutics offer several advantages including, effective treatment of numerous clinical conditions and degenerative disorders. Pipeline Overview of Oral Peptide and Protein-based Therapeutics. Oral Protein / Peptide-based Drugs. Oral Protein / Peptide-based Drugs.

Protein 52

Protein Drug Delivery Drugs Drug Delivery Systems 52

Roots Analysis

MAY 2, 2022

Owing to significant advantages over conventional expression systems, such as low production costs, product safety, and ease of scaling up, plants are being widely recognized as a potential platform for the development and manufacturing of wide range of biopharmaceuticals. Key Developments in Plant-based Biologics Domain.

Protein 52

Protein Development Manufacturing Marketing 52

XTalks

JANUARY 29, 2021

Oncology products monopolise the list of best-selling drugs. Several oncology products now have “blockbuster” status where sales exceed $1 billion annually. This is relevant for clinical trials as more regulators require evidence of efficacy in comparison to the standard of care, which is likely to be one of the blockbuster products.

Clinical Trials 104

Clinical Trials Clinical Trials Production Trials 104

BioTech 365

FEBRUARY 17, 2021

PRESS RELEASE Biotest is the first plasma protein manufacturer in Germany to produce an investigational hyperimmunoglobulin preparation against … Continue reading → DGAP-News: Biotest AG / Key word(s): Research Update 18.02.2021 / 07:00 The issuer is solely responsible for the content of this announcement.

Protein 40

Protein Manufacturing Production Research 40

XTalks

OCTOBER 22, 2020

To achieve transparency and actionability of data, pharmaceutical companies are evolving their manufacturing processes by digitalizing the data from all of their equipment. There is always a constant social pressure to deliver a drug product to the market to treat diseases that have no current cure or treatment.

Manufacturing 98

Manufacturing Development Production Gene Therapy 98

Roots Analysis

AUGUST 29, 2023

In this context, it is worth highlighting those 14 biopharmaceutical products ( including cell therapies, gene therapies, monoclonal antibodies and recombinant proteins ) were approved in the US alone, in 2021. As a result, biopharmaceutical contract manufacturing has picked up pace in the recent years.

Contract Manufacturing 40

Contract Manufacturing Manufacturing Gene Therapy Marketing 40

Roots Analysis

AUGUST 29, 2023

In this context, it is worth highlighting those 14 biopharmaceutical products ( including cell therapies, gene therapies, monoclonal antibodies and recombinant proteins ) were approved in the US alone, in 2021. As a result, biopharmaceutical contract manufacturing has picked up pace in the recent years.

Contract Manufacturing 40

Contract Manufacturing Manufacturing Gene Therapy Marketing 40

Pharmaceutical Technology

MARCH 10, 2023

Freeze drying is a crucial technique to prolong the shelf life of pharmaceutical products. Also known as lyophilisation, the technique stabilises and preserves sensitive products such as biologics, and diagnostic kits, in a permanently storable state.

Manufacturing 147

Manufacturing Production Containment Antibody 147

XTalks

JUNE 10, 2021

Amazon’s Launchpad program empowers and accelerates start-up businesses that will sell their products amazon.com. The company has a team of entrepreneurs that are experts in the consumer-packaged goods, manufacturing, logistics and distribution categories that contribute to the development of PlantFuel.

Production 93

Production Protein Packaging Packaging 93

Roots Analysis

JANUARY 18, 2024

Plasma fractionation, a critical process in the field of medical science, involves the separation of various components present in blood plasma to create valuable therapeutic products. The success of plasma fractionation companies hinges upon the precise isolation and purification of specific proteins and molecules from plasma.

Manufacturing 40

Manufacturing Marketing Production Protein 40

XTalks

JULY 19, 2022

The two-dose protein-based, adjuvanted vaccine has been authorized for use in adults 18 years of age and older for the prevention of COVID-19 caused by SARS-CoV-2. The vaccine authorization was held up for several weeks due to changes Novavax had made to the vaccine’s manufacturing processes. billion in taxpayer funding.

Vaccination 94

Vaccination Vaccine Protein Clinical Trials 94

BioPharma Reporter

JANUARY 22, 2024

Abzena, an end-to-end CDMO for biologics and bioconjugates, has launched AbZelect and AbZelectPRO cell line development (CLD) platforms to accelerate cell lie production for manufacturing antibodies and recombinant proteins.

Protein 52

Protein Antibody Manufacturing Production 52

The Pharma Data

OCTOBER 26, 2020

The agreement covers the gene therapy program targeting OTOF (OTOF-GT), the gene encoding the otoferlin protein. Through this agreement, Novasep’s expertise in the field of viral vector development and manufacturing is once again recognized and valued,” said Cedric Volanti , Novasep’s President of Biopharma Solutions. About Sensorion.

Gene Therapy 52

Gene Therapy Gene Manufacturing Production 52