Fierce Pharma

NOVEMBER 22, 2023

Unable to scale up its manufacturing fast enough to meet the spiraling demand for its GLP-1 weight loss products, Novo Nordisk is employing a new strategy—reducing production of diabetes drug Victo | Unable to scale up its manufacturing fast enough to meet the spiraling demand for its GLP-1 weight loss products, Novo Nordisk is employing a new strategy—reducing (..)

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BioSpace

SEPTEMBER 12, 2023

The company plans to launch up to 15 new products and bring up to 50 new candidates to the clinic over the next five years as part of its growth plan, while scaling down COVID-19 manufacturing.

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pharmaphorum

APRIL 6, 2022

The growth of a start-up after obtaining Series A funding is a transformational phase when scaling up the company becomes critical. The CEO can experience pressure to deliver on the revenue growth goals, whilst still developing their product, growing the team, and implementing core processes for the company.

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BioPharma Reporter

AUGUST 24, 2021

Swedenâs Biotage says its expanded facility in the UK will allow it to triple its production capacity for equipment crucial in the supply chain for the production of mRNA vaccines, and thus eliminating a bottleneck for COVID-19 vaccines.

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Fierce Pharma

MAY 15, 2024

following | Galapagos has teamed up with the largest blood supply network in the U.S. to help establish decentralized CAR-T production on a national scale.

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The Pharma Data

MARCH 20, 2021

Fermentation is used in the production of renewable feedstocks for food products and ingredients, beverages, pharmaceutical compounds, nutraceuticals, through to fine and bulk chemicals. In this regard, Martin Hoogedoorn, Product Specialist at Elscolab Nederland B.V., Faster scale-up.

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XTalks

NOVEMBER 29, 2023

This collaboration is set to usher in a new era of sustainable and nutritious protein production, leveraging Ginkgo Bioworks’ expertise in cell programming and biosecurity. This process ensures optimal protein expression and functionality at a commercial scale. Ginkgo Bioworks has vast experience partnering with food tech firms.

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Drug Discovery World

MAY 7, 2024

Where the bottlenecks of achieving higher cell density and higher titers were once thought to be issues of the past, hurdles have now shifted to achieving speed and scale in mAb production without sacrificing quality. DC: Antibodies have and remain a large product class within the biopharmaceutical market.

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Fierce Pharma

NOVEMBER 15, 2023

. | After reporting a sizable revenue decline for its BMS-parntered multiple myeloma cell therapy in 2023’s third quarter, 2seventy stands out as a prime example of the dangers of scaling up a process before suffering lower-than-expected demand, one group of analysts contends.

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Sales Production Drugs 115

Pharmaceutical Technology

AUGUST 2, 2022

Samsung Biologics and GreenLight Biosciences have completed the initial commercial-scale engineering run for their messenger ribonucleic acid (mRNA) Covid-19 vaccine under their manufacturing collaboration. Furthermore, the mRNA synthesis reaction of GreenLight had a titer of 12g/L at a commercial scale and yielded 650g mRNA.

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BioTech 365

JANUARY 12, 2021

Lestrem and Zwingenberg, 13th January 2021 Roquette and BRAIN Group agree on production scale-up … Continue reading → Biotechnology Research And Information Network AG / Key word(s): Agreement 13.01.2021 / 08:00 The issuer is solely responsible for the content of this announcement.

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Production Protein Research 40

BioTech 365

DECEMBER 22, 2020

Genprex Completes Manufacturing Scale-Up for Clinical-Grade Production of REQORSA™ Immunogene Therapy for Upcoming Acclaim-1 and Acclaim-2 Clinical Trials For Lung Cancer Genprex Completes Manufacturing Scale-Up for Clinical-Grade Production of REQORSA™ Immunogene Therapy for Upcoming Acclaim-1 and Acclaim-2 Clinical Trials For … (..)

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Clinical Trials Clinical Trials Manufacturing Production 40

Drug Discovery World

NOVEMBER 27, 2023

A complex journey Biotherapeutics discovery and development upstream encounters challenges in cell line development (CLD), clone screening and characterisation, scale up, and eventually production. Stable clonal cell banks are used for GMP production of the final drug product. Metab Eng 2020;57:203.

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BioPharma Reporter

MAY 24, 2023

Purolite, an Ecolab company based in Pennsylvania, is a leading manufacturer of healthcare, pharmaceutical and life science products. The company is concerned with projects involving purification of mRNA vaccines and monoclonal antibodies for cancer-treatment drugs, among others.

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Life Science Antibody Manufacturing Vaccination 52

Pharma Mirror

MAY 31, 2023

In the face of increasing global health challenges, the development and production of vaccines have become paramount. One critical aspect is the ability to scale up manufacturing processes to meet the growing demand for viral vector-based vaccines.

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Vaccination Vaccine Manufacturing Production 130

Drug Discovery World

OCTOBER 3, 2022

Biosynth are experts in complex chemistry, peptides and key biological raw materials, providing more than half a million research products plus end-to-end manufacturing including discovery, optimisation, and scale up. Biosynth can ensure your project succeeds first time, with innovative expertise across chemistry and peptides.

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Production Life Science Manufacturing Research 52

pharmaphorum

DECEMBER 4, 2020

Pfizer slashed its production targets for its COVID-19 vaccine because of a lack of raw materials for its supply chain, according to press reports. A Pfizer spokesperson told Reuters that the “scale-up of the raw material supply chain took longer than expected”. million doses.

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Pharmaceutical Technology

SEPTEMBER 7, 2022

Bharat Biotech carried out the product development linked to preclinical safety assessment, large-scale production scale-up, as well as the development of formulation and delivery device, including trials in humans. iNCOVACC has been designed for efficient distribution and easy administration.”.

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XTalks

MAY 27, 2021

To help boost production of its COVID-19 vaccine, Moderna has enlisted the services of Samsung Biologics , a contract development and manufacturing organization (CDMO) based in South Korea. Last month, Moderna announced it is upping its COVID-19 vaccine targets, aiming for 800 million to 1 billion doses this year and 3 billion doses by 2022.

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Manufacturing Production Vaccination Vaccine 98

Drug Discovery World

AUGUST 22, 2023

Claire D’Abreau-Hayling, Chief Scientific Officer at Sandoz, examines how generic products can relieve industry pressure and improve access to essential medicines. Off-patent medicines today account for about 80% of global prescriptions at an estimated 20% of the total cost. Complex generics comprise a diverse range of products.

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Pharmaceutical Technology

NOVEMBER 24, 2022

Additionally, the transfer of technology will build and validate capacity for scaling up Good Manufacturing Process (GMP), domestic production of clinical trial products and end-to-end vaccine manufacturing in Africa for regional and global use.

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Vaccination Vaccine Development Manufacturing 147

Pharmaceutical Technology

AUGUST 25, 2022

Sonoma Biotherapeutics has signed a lease agreement for setting up an 83,000ft² research and development (R&D) and manufacturing centre for cell therapies. A cGMP-compliant production facility will be housed at the centre for manufacturing cell products at scale.

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Manufacturing Engineer Gene Therapy Production 130

STAT News

JANUARY 17, 2023

We hope your day is productive and meaningful. … After mobilizing to quickly develop and manufacture a Covid-19 vaccine, Johnson & Johnson has vastly scaled back efforts to produce the shots as it faces slumping demand , The Wall Street Journal reports. government, has not lived up to expectations.

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Production Vaccination Vaccine Manufacturing 98

Pharma Mirror

SEPTEMBER 19, 2021

With this agreement, HTL will exclusively develop, scale-up, and supply a high-grade functional injectable Hyaluronic Acid based active ingredient, Sodium Hyaluronate Lipoate Formate (SHLF), for a major part of BMG Pharma’s products.

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Pharmaceutical Technology

SEPTEMBER 28, 2022

Chimerix entered a ten-year contract worth up to $680m with the US Government in August this year for delivering up to 1.7 Apart from product purchase, the contract also includes $12m worth of reimbursed post-marketing activities. Emergent will also make a further payment of up to $12.5m

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Vaccination Vaccine Sales Production 147

Pharmaceutical Technology

APRIL 6, 2023

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has granted ADvantage Therapeutics’ immunotherapy AD04 an Innovation Passport for the treatment of Alzheimer’s disease. A recent wave of monoclonal antibodies, including the FDA-approved Eisai / Biogen ’s Leqembi (lecanemab), is expected to shake up the space.

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FDA Approval Licensing Licensing Antibody 264

Drug Discovery Today

JANUARY 13, 2020

The novel silicon chip is a key component of Evonetix’s desktop DNA platform which, once fully developed, will facilitate and enable the rapidly growing field of synthetic biology.

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DNA Production Gene Manufacturing 40

Scienmag

JULY 14, 2021

Credit: The University of Texas at Austin Urea is a critical element found in everything from fertilizers to skin care products. Large-scale production of urea, which is naturally a product of human urine, is a massive undertaking, making up about 2% of global energy use and emissions today.

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Engineer Production Scientist 98

pharmaphorum

FEBRUARY 14, 2022

A recent report has found that R&D productivity rose vertiginously during 2021, but how much of this was organic and how much can be attributed to the pandemic? The pandemic also saw a reduction in the overall development cycle of a product, which has been growing in recent years. In 2020, the development cycle averaged 7.14

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Production Clinical Trials Clinical Trials Sales 98

Pharmaceutical Technology

MAY 17, 2023

AGC Biologics has introduced the BravoAAV and ProntoLVV viral vector platforms that offer quick clinical and commercial production and release of good manufacturing practices (GMP). The new platforms have production at various scales in suspension and adhesion up to 2,000l and 750l, respectively.

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Gene Therapy Gene Manufacturing Production 130

Drug Discovery World

MARCH 22, 2023

Download this eBook to learn more about process development and manufacturing in the mRNA space to enable successful scale-ups of mRNA production for therapeutic applications.

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Pharmaceutical Technology

MARCH 31, 2023

The company will construct the new advanced mRNA facility, which is claimed to be Moderna’s first mRNA manufacturing facility in Africa and is expected to have the capacity to produce up to 500 million vaccine doses annually.

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pharmaphorum

OCTOBER 18, 2022

One of the first actions by GSK’s recently appointed chief scientific officer, Tony Wood, has been to expand a partnership with Tempus aimed at improving the big pharma’s R&D productivity, starting with its cancer pipeline. The post GSK turns to AI specialist Tempus for R&D productivity boost appeared first on.

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Pharmaceutical Technology

MAY 25, 2023

ElevateBio has raised $401m in a Series D financing round for advancing its technology platforms to expedite the design, production and development of cell and gene therapies. The partnership will enable the development of up to seven programmes.

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Gene Therapy Gene Gene Editing Manufacturing 243

Drug Discovery Today

JULY 13, 2020

CPI today announced a partnership with Excivion Ltd, Cambridge, to optimise the manufacture of their novel Zika vaccine antigen candidate, Zika-HX, an integral component of any future vaccine formulation.

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Pharmaceutical Technology

JULY 18, 2022

With the ever-rising costs of bringing a drug to market, pharmaceutical companies are increasingly looking at how they can improve the efficiency of their entire product development and drug commercialisation process. And these are just a few of the surprise challenges that a manufacturer might face during scale-up.

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Drug Discovery World

MARCH 22, 2023

Download the eBook to learn more about process development and manufacturing in the mRNA space to enable successful scale-ups of mRNA production for therapeutic applications.

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Manufacturing Development In-Vitro Vaccination 52