Scienmag

JANUARY 18, 2022

CLEVELAND—Researchers from Case Western Reserve University have identified a new mechanism by which a protein known for repairing damaged DNA also protects the integrity of DNA by preserving its structural shape.

DNA 84

DNA Research Protein 84

Scienmag

APRIL 18, 2022

From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible. Credit: (Photo: Jess Hunt-Ralston / Georgia Tech) From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible.

Protein 79

Protein DNA Research 79

Bio Pharma Dive

MAY 13, 2021

With $82 million in hand, Flare Therapeutics is looking to create precision cancer drugs by going after a type of protein called transcription factors.

Regulation 234

Regulation DNA Protein Drugs 234

Medical Xpress

FEBRUARY 7, 2023

University of Saskatchewan (USask) College of Medicine graduate student Ananna Arna dedicated a research project to examine how genetics and DNA replication play a role in leukemia development. Of that 7,000, it is estimated that nearly half will face mortality.

DNA 74

DNA Protein Genetics Medicine 74

Drug Discovery World

NOVEMBER 29, 2022

Using artificial intelligence, researchers at Chalmers University of Technology, Sweden have succeeded in designing synthetic DNA that controls the cells’ protein production. . First it was about being able to fully ‘read’ the DNA molecule’s instructions.

DNA 52

DNA Development Research Drugs 52

Scienmag

SEPTEMBER 28, 2021

Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is a protein that tends to accumulate in increasing amounts, and the amount is strictly controlled by the splicing of TDP-43. […].

DNA 108

DNA Protein 108

STAT News

SEPTEMBER 16, 2022

Intellia Therapeutics said Friday the first six patients to receive its CRISPR-based treatment for a genetic swelling disorder have safely had small, corrective changes made to dysfunctional DNA inside their liver cells.

DNA 142

DNA Gene Editing In-Vivo Genetics 142

Scienmag

NOVEMBER 20, 2021

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

DNA 96

DNA Gene Expression Genome Genomics 96

Drug Discovery World

DECEMBER 4, 2023

A novel DNA vaccine in combination with chemotherapy has demonstrated promising clinical results against a deadly form of ovarian cancer. The investigational compound Elenagen is an experimental DNA therapy that consists of a circular piece of DNA called a plasmid that includes a gene for a human protein called p62/SQSTM1.

DNA 59

DNA Packaging Packaging Vaccination 59

BioTech 365

MARCH 10, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Sharing shears: Conserved protein segment activates molecular DNA scissors for DNA repair.Scientists at Tokyo Institute of Technology (Tokyo Tech) have uncovered mechanisms underlying the activation of the … Continue reading (..)

DNA 40

DNA Protein Research 40

Medical Xpress

MARCH 23, 2023

DNA is our body's instruction manual. It contains all the information that our cells need to make proteins and other molecules vital for our development, growth and survival.

DNA 56

DNA Containment Protein Development 56

Drug Discovery World

AUGUST 16, 2023

Samir Ounzain , PhD, CEO & Co-Founder of HAYA Therapeutics, looks at how a better understanding of our DNA can lead to increased activity for RNA therapeutics. In actuality, the protein-coding portion of our genome is comparable in identity and number with the humble fruit fly or worm.

RNA 52

RNA Genome Genomics DNA 52

pharmaphorum

AUGUST 23, 2021

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

DNA 98

DNA Vaccination Vaccine Genetic Engineering 98

Scienmag

APRIL 8, 2021

Credit: © Terence Strick The Mfd protein repairs bacterial DNA, but can also, to scientists’ surprise, promote mutation. Understanding this second “role” of the Mfd protein opens up opportunities for combating antibiotic resistance, and also the resistance of tumours to anti-cancer drugs and therapies.

Protein 98

Protein DNA Scientist Drugs 98

Drug Discovery World

OCTOBER 25, 2022

Recombinant production is a field in which Sino Biological has extensive expertise – the company boasts several platforms to use recombinant DNA technology for the manufacturing of a variety of proteins and antibodies to expedite the process of novel drug identification and validation, for example. . Listen here.

Recombinant DNA Technology 52

Recombinant DNA Technology DNA Drugs Protein 52

Drug Discovery World

OCTOBER 25, 2022

Recombinant production is a field in which Sino Biological has extensive expertise – the company boasts several platforms to use recombinant DNA technology for the manufacturing of a variety of proteins and antibodies to expedite the process of novel drug identification and validation, for example. .

Recombinant DNA Technology 52

Recombinant DNA Technology DNA Drugs Protein 52

BioTech 365

JULY 23, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers discover that protein switches functions to regulate DNA replication.One protein. One mechanism of action. Two biologically opposite effects.

DNA 40

DNA Protein Regulation Research 40

Drug Discovery World

FEBRUARY 14, 2024

While a typical chemisty, manufacturing and controls (CMC) timeline from DNA to Investigational New Drug (IND) application in 2015 would have been approximately 24 months, by 2023 the same pathway was expected to take only 10 months. In particular, we must work to accelerate recombinant protein vaccine development.

Protein 59

Protein Vaccination Vaccine Manufacturing 59

Scienmag

NOVEMBER 14, 2021

In a study with lab-grown mouse cells, Johns Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell’s “command center” — its nucleus — is key to ensuring that DNA inside it remains orderly. The new experiments distinguish the role of the protein, […].

DNA 79

DNA Protein Medicine Research 79

BioTech 365

AUGUST 14, 2020

$207.50 (6 Bids)End Date: Tuesday Aug-18-2020 8:06:33 PDTBid now | Add to watch list Biotech365 : Shimadzu BioSpec-1601 UV-1601 DNA / Protein / Enzyme Analyzer BioMarketplace You want to propose your products or a Biotech Company, a Biotech Tool or … Continue reading →

DNA 40

DNA Protein Production 40

BioTech 365

SEPTEMBER 21, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Regulator proteins or symphonies of genes: Statistical modeling points way toward unified theory for DNA folding.At more than 2 meters long, the human DNA molecule uses intricate … Continue reading →

DNA 40

DNA Regulation Protein Gene 40

BioTech 365

JUNE 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study reveals structural changes of a key protein involved in DNA repair.Researchers of the University of Oulu, Finland, have for the first time uncovered the molecular structure … Continue reading →

DNA 40

DNA Protein Research 40

BioTech 365

AUGUST 2, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Atomic-level, 3-D structure of MUTYH protein opens small window into DNA repair mechanism.Researchers have analyzed the three-dimensional structure of a protein that suppresses the development of colorectal … Continue reading (..)

DNA 40

DNA Protein Development Research 40

BioTech 365

JUNE 25, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: MeCP2: A binding protein that prevents DNA from being wrapped up in nucleosomes.A team of researchers working at the Institute of Genetics and Molecular and Cellular Biology … Continue reading →

DNA 40

DNA Protein Genetics Research 40

Scienmag

SEPTEMBER 28, 2020

Brazilian research group shows that valproic acid (VPA), used to treat epilepsy since the 1960s, modulates gene expression in tumor gene models and acts on DNA conformation and the histones in chromatin Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of (..)

DNA 70

DNA Gene Expression Protein Gene 70

Roots Analysis

JUNE 1, 2022

DNA cloning is the field of synthetic biology which can be helpful to understand the effect of mutation on a particular gene. Many diseases that can be treated using DNA cloning, such as leukemia and sickle cell anemia, involving the replacement of defected gene. DNA Cloning Kit Providers – Current Market Landscape.

DNA 52

DNA Genetics Reagent Marketing 52

BioTech 365

AUGUST 10, 2020

$2,950.00End Date: Monday Aug-31-2020 14:55:52 PDTBuy It Now for only: $2,950.00Buy It Now | Add to watch list Biotech365 : NEW Thermo Invitrogen Qubit 4 DNA RNA Oligo Ion Protein Fluorometer w/Warranty BioMarketplace You want to propose your products or … Continue reading →

RNA 40

RNA DNA Protein Production 40

Roots Analysis

DECEMBER 12, 2021

DNA data storage involves encoding and decoding binary data to and from synthesized strands of DNA. DNA data storage is an innovative technology that works by encoding large digital data sequences of binary form (0s and 1s) into DNA sequences (Adenine (A), Guanine (G), Cytosine (C) and Thymine (T)). DNA Storage.

DNA 52

DNA Research Engineer Marketing 52

BioTech 365

JANUARY 17, 2022

Targeted Immunotherapy in Oncology Market Research Report 2021: Development of New Targeted Immunotherapies, Particularly Those that Deliver Therapeutic DNA and Proteins – ResearchAndMarkets.com Targeted Immunotherapy in Oncology Market Research Report 2021: Development of New Targeted Immunotherapies, Particularly Those that Deliver … (..)

DNA 40

DNA Protein Marketing Development 40

Medical Xpress

MARCH 16, 2023

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

DNA 98

DNA Protein 98

Outsourcing Pharma

FEBRUARY 1, 2024

A company building a pipeline of small molecule drugs targeting novel proteins across the DNA mismatch repair (pathway) has announced a further extension to its series B financing round.

DNA 84

DNA Protein Drugs Regulation 84

Scienmag

MAY 7, 2021

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling […]. (..)

DNA 62

DNA Regulation Genome Genomics 62

Scienmag

APRIL 14, 2021

Credit: Surajit Chatterjee To better understand how RNA in bacteria gives rise to protein–and along the way, target these processes in the design of new antibiotics–researchers are turning their attention to the unique way this process happens in bacteria.

RNA 82

RNA Bacteria Protein Research 82

Scienmag

SEPTEMBER 15, 2021

Scientists from the University of Bradford have discovered a DNA protein ‘switch’ that could help in the treatment of cancer and dementia. Credit: University of Bradford Scientists from the University of Bradford have discovered a DNA protein ‘switch’ that could help in the treatment of cancer and dementia.

DNA 40

DNA Scientist Protein 40

pharmaphorum

SEPTEMBER 14, 2021

Startup Rome Therapeutics has raised $77 million in second-round financing to help mine sequences of DNA – which were dismissed for years as ‘junk’ – for hidden treasure. Most drug discovery programmes target the roughly 2% of the human genome which encodes for protein.

DNA 52

DNA Immune Response Genome Genomics 52

FDA Law Blog

MARCH 5, 2024

Gaulkin & Riëtte van Laack — As readers of this blog know, there is a lot of contention about the naming of alternative protein products (APPs), including both plant-based and cell-cultured alternatives for (traditional) animal products. By Sophia R. We’ve previously blogged about this ongoing battle here , here , here , and here.

Protein 59

Protein Production DNA Containment 59

Scienmag

OCTOBER 13, 2020

Researchers find that simple DNA-peptide interactions create a surprising diversity of compartmentalised higher-ordered phase behaviours, suggesting that these polymers’ primordial interactions helped create modern complex biological structures. For example, each human cell contains about 2 meters worth of DNA, but this is […].

DNA 52

DNA Containment Protein Research 52