STAT News

JULY 29, 2022

Among the small bunch of billionaires that the local biotech industry has created, Tim Springer may be the only one who regularly rides his bike to work in the Longwood Medical Area, where his ID tag identifies him simply as a “staff scientist.”

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World of DTC Marketing

SEPTEMBER 24, 2021

I remember when Biogen was an exciting new biotech based in Westin. Then, against the advisory panel’s advice, Aduhelm was approved, but insiders within the industry criticized both the FDA and Biogen weren’t sold on the drug or its price tag. He has zero credibility with the HCP community.

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World of DTC Marketing

SEPTEMBER 7, 2022

In pharma, growth depends on new products with hefty price tags when over 80% of voters want lower costs for their prescription drugs. Rather than investing more in R&D, most pharma companies feel its more cost-effective to buy small biotech companies developing unique molecules that can find a market niche.

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pharmaphorum

JUNE 12, 2022

The panel voted 13 to 0 on the question of whether beti-cel’s benefits outweighed the risks of the gene therapy in patients with beta thalassaemia who are dependent on blood transfusions, in a dream result for the biotech which just a few weeks ago was expressing doubts about its ability to continue as an operating concern.

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The Pharma Data

AUGUST 18, 2020

Bristol Myers Squibb has scooped up the sole rights to the interleukin-12 (IL-12) immunotherapy programme of Massachusetts-based biotech Dragonfly Therapeutics, handing over $475 million for the privilege.

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pharmaphorum

NOVEMBER 16, 2021

“We look forward to the full technology appraisal guidance (TAG) which is due to be published in early December 2021,” he added. Cenobamate was originally developed by South Korean biotech SK Biopharmaceuticals, and was approved as Xcopri in the US in 2019. The drug made almost $17 million in US sales in the third quarter.

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pharmaphorum

AUGUST 25, 2022

It joins a number of other BCMA-directed therapies for multiple myeloma, including GSK’s first-to-market antibody-drug conjugate Blenrep (belantamab mafodotin), Bristol-Myers Squibb/bluebird bio’s CAR-T therapy Abecma (idecabtagene vicleucel) and J&J/Legend Biotech’s CAR-T Carvykti (ciltacabtagene autoleucel).

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pharmaphorum

AUGUST 21, 2022

The biotech hasn’t revealed much information about the reasons for the delay in getting approval, but said in an SEC filing in June this year that it had agreed to “post-marketing commitments” proposed by the FDA, without going into details.

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pharmaphorum

OCTOBER 21, 2021

Vounatsos also insisted that Aduhelm’s price tag has not been a factor discouraging treatment with the drug. Biogen stumped up $1.525 billion upfront for rights to the drug and another Sage candidate for neurological diseases last year, when the expectation was that Aduhelm was unlikely to get FDA approval.

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XTalks

NOVEMBER 24, 2022

The Hemgenix approval was granted to CSL Behring , a rare disease biotech company based in Pennsylvania, which developed Hemgenix jointly with gene therapy biotech uniQure. Related: Roctavian, the First Hemophilia A Gene Therapy, Attains EC Approval.

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pharmaphorum

DECEMBER 12, 2022

Dutch biotech Argenx is on course to add another rare disease indication to the label of its FcRn blocker Vyvgart – primary immune thrombocytopenia (ITP) – thanks to new data reported at the ASH annual meeting.

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pharmaphorum

MARCH 23, 2022

Vyvgart (efgartigimod alfa) became the first drug in the FcRn class to be approved by the FDA last December, and despite a $225,000 annual price tag is predicted to make relatively modest sales in its IV version, which will compete with other IV gMG drugs like AstraZeneca/Alexion’s C5 inhibitor Soliris (eculizumab).

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XTalks

APRIL 18, 2024

Previously, Roche secured an FDA breakthrough tag for another one of its Alzheimer’s blood tests that detects levels of pTau-181 and ApoE4 (apolipoprotein e4). The incidence of dementia is growing worldwide, with 75 percent of cases remaining undiagnosed.

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pharmaphorum

DECEMBER 23, 2022

price tag of $475,000 when it was first launched in 2017 – and it becomes apparent that these may not be desirable treatment options for every patient and in every setting. Add to this the considerable cost of these medications – the first approved CAR-T, Novartis’ Kymriah (tisagenlecleucel), had a U.S. Oral therapy data presented at ASH.

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pharmaphorum

JANUARY 11, 2021

US biotech bluebird bio has announced plans to split into two this year, with a separate oncology business spinning off as the company prepares to bring its products to market. million price tag. Zynteglo is already in beta-thalassemia in Europe, where the company will seek to expand access despite its hefty $1.8

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Drug Discovery World

MAY 22, 2023

But are these price tags a barrier to access? Biotech and pharma are actively working with payers and insurers to deliver on equitable pricing models that ensure access. million per dose. Simply, yes, as we saw when the European Commission rejected the price point for bluebird bio’s Zynteglo.

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pharmaphorum

JULY 25, 2022

The new drug is one of two bispecifics for multiple myeloma in the late-stage pipeline of J&J’s Janssen division stemming from its longstanding and fertile collaboration with Danish biotech Genmab, along with talquetamab which binds to CD3 and GPRC5D.

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Drug Discovery World

OCTOBER 3, 2022

The seminars will include high profile speakers from pharma and biotech covering topics such as The Lab of the Future is Now, Data Handling and Choosing the Right Informatics System, The Sustainable Lab and The Remote Lab: Is This the Future? The seminars will be held in a dedicated Tech Theatre, centrally located in the exhibition hall.

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Drug Discovery World

JANUARY 30, 2024

Joel Eichmann, Co-Founder and Managing Director, Green Elephant Biotech, agrees that prices need to come down significantly for CGT to be widely available. Other Challenges: Limited insurance coverage: Many insurance companies are hesitant to cover CGTs due to their high price tags and limited long-term data.

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XTalks

DECEMBER 21, 2022

The past year has been a strong one for life sciences industries, from pivotal gene therapy approvals to continued innovations in the biotech and medical device spaces. And almost every time a new gene therapy approval was awarded, it would more often than not break the previous ‘world’s most expensive drug’ record.

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pharmaphorum

NOVEMBER 27, 2022

Fully integrated and automated ingredient to consumer batch tracking using barcoding, RFID tagging, or IoT temperature logging and timestamping significantly reduces the chance of these mix-ups, providing complete traceability records from ingredient manufacturer to patient, and ensures the safety of the product. About the author.

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Delveinsight

DECEMBER 3, 2020

It has been speculated that modifications to the epigenome drive cell ageing, especially a process known as DNA methylation, by which methyl groups are tagged onto DNA. Merck first collaborated with the biotech in a pact worth nearly USD 700 million two years ago, with an aim on a series of solid tumour targets.

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The Pharma Data

OCTOBER 9, 2021

This designation is predicated on data showing that gantenerumab significantly reduced brain amyloid pillar, a pathological hallmark of Notice, in the ongoing SCarlet RoAD and Marguerite RoAD open- tag extension trials, as well as other studies.

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pharmaphorum

AUGUST 26, 2022

The US biotech claimed conditional marketing approval from the European Commission for Roctavian (valoctocogene roxaparvovec) as a treatment for adults with severe haemophilia A, who don’t have a history of developing the antibodies that inhibit the activity of blood-clotting protein Factor VIII. million spread over five years.

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XTalks

JANUARY 19, 2024

Radiobiological and Clinical Considerations from CRO and Emerging Biotech Radiopharmaceuticals are medicinal formulations containing radioisotopes that are used in the field of nuclear medicine primarily for the diagnosis and treatment of various diseases, particularly cancer. Anderson, PharmD, PhD, Radiation Clinical Pharmacologist, A.

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pharmaphorum

MARCH 27, 2022

Carvykti – developed by J&J with China’s Legend Biotech – was approved on the back of a single arm, open-label, clinical trial in 113 patients – CARTITUDE-1 – which showed an overall response rate of 84%, with signs of the cancer disappearing altogether in 69% of recipients.

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Drug Discovery World

FEBRUARY 21, 2023

I think the biotech space for software is lagging behind the tech industry. How can you track and tag information so that when someone looks at it a week later or three years later, the data still makes sense?” There is also an issue with metadata during experiments.

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pharmaphorum

FEBRUARY 26, 2021

2017 saw J&J make its biggest ever acquisition deal after fighting off competition from Sanofi to acquire Swiss biotech Actelion for $30 billion. The company has many interesting drugs in its pipeline, including a CAR-T therapy developed in partnership with Legend Biotech.

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pharmaphorum

DECEMBER 2, 2020

US biotech TG Therapeutics has begun a rolling filing with the FDA for its combination therapy for chronic lymphocytic leukaemia, in a challenge to Roche. The New York-based firm has requested approval for the combination of its anti-CD20 antibody ublituximab and umralisib, an oral drug that inhibits PI3K-delta and CK-1 epsilon.

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Drug Discovery World

NOVEMBER 13, 2023

Jens Frauenfeld, PhD, Founder, CEO, Salipro Biotech, on: ‘Structure-function studies of salipro-CXCRs for antibody development’. Fabian Mohr, PhD, Vice President Research & Development, IBA Lifesciences, on: ‘Developing a robust affinity tag platform using engineered streptavidin’.

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Drug Discovery World

NOVEMBER 9, 2023

Thereafter, there will be the following presentations: Georgios Skretas, PhD, Director, Institute for Bio-innovation, Biomedical Sciences Research Center “Alexander Fleming;” Founder & CEO, ResQ Biotech, on: ‘Development of specialised bacterial strains for high-level production of recombinant membrane proteins’.

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The Pharma Data

MAY 5, 2021

Pharma & Biotech. Esker, a new biotech startup, launches with plans to make targeted immune drugs ( BioPharma Dive ). AbbVie’s Humira regains top pharma TV spender spot, while sibling brands Rinvoq and Skyrizi tag along ( Fierce ). Medtech. Medtech.

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