pharmaphorum

AUGUST 21, 2022

Shares in Axsome Therapeutics have rocketed on FDA approval of its depression therapy Auvelity (formerly AXS-05) – a year after its approval was held up by the regulator.

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pharmaphorum

JUNE 12, 2022

Beti-cel has already been approved for marketing in Europe as Zynteglo, with a price tag of around $1.8 million price tag, saying its ability to help patients reach sustained transfusion independence justified its high price. Eli-cel was also previously approved in Europe as Skysona.

Gene Therapy 58

Gene Therapy Gene Marketing Trials 58

Drug Discovery World

JUNE 14, 2023

We have now our lead product in a Phase I/II study, which is a HER-2 directed tag T cell product for patients with HER-2 positive solid tumours. We have come a long way with checkpoint inhibitors and I think that cell therapy, as the immune cell in itself, provides one of the best opportunities to go about that.

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Research Engineer In-Vivo Production 52

Drug Discovery World

MAY 22, 2023

Large pharma involvement in advanced therapies has seen ebbs and flows, with AstraZeneca taking a larger stake in the market and Takeda developing its automation and digital capabilities, but also with GSK letting go of its CGT projects, along with most of the staff involved in its R&D. But are these price tags a barrier to access?

Gene Therapy 52

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The Pharma Data

MARCH 23, 2022

This special enzyme, once fused to Ebola virus polymerase, enables the polymerase to add a molecular tag to any other protein it interacts with. By fishing out proteins that contain this unique tag, researchers could map out the complex series of Ebola virus polymerase-host protein interactions.

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Protein Genome Genomics Research 52

pharmaphorum

DECEMBER 23, 2022

price tag of $475,000 when it was first launched in 2017 – and it becomes apparent that these may not be desirable treatment options for every patient and in every setting. Add to this the considerable cost of these medications – the first approved CAR-T, Novartis’ Kymriah (tisagenlecleucel), had a U.S.

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Development Drugs Clinical Development Antibody 52

The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins. . EMERYVILLE, Calif.

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Vaccination Vaccine Trials Protein 52

XTalks

OCTOBER 12, 2022

However, the role of MRI in new drug clinical trials can involve diagnosis of lesions and determination of their severity, early identification of therapeutic responders to drug treatment and treatment monitoring and follow-up. For most of this time, MRI mainly was used for qualitative interpretation and simple structural measurements.

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Clinical Trials Clinical Trials Trials Drugs 93

Delveinsight

FEBRUARY 25, 2021

Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. Beam announced that it paid USD 120 million upfront to acquire Guide Therapeutics in an all-stock agreement.

DNA 52

DNA In-Vivo Genetics Medicine 52

XTalks

AUGUST 23, 2021

Now that [aducanumab] is approved, how will this affect clinical trials going forward?”. With this in mind, here are six considerations for Alzheimer’s clinical trials going forward and how some of the experts at AAIC 2021 plan to tackle these challenges. Are Placebo Arms Still Ethical in Alzheimer’s Clinical Trials?

Clinical Trials 52

Clinical Trials Clinical Trials Trials Drugs 52

XTalks

AUGUST 17, 2020

“And that’s where the brilliant protein engineering comes in because it’s all about understanding the structural aspects and the spatial organization, the linkers between the domains and the valency between the domains, to then come up with a core structure that can go after a particular T cell.”. Targeting HPV-Induced Head and Neck Cancer.

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Protein Engineer Immune Response In-Vivo 98

The Pharma Data

NOVEMBER 15, 2020

Peng Liang , Founder and Chief Scientific Officer of Clover and inventor of the Trimer-Tag© technology, says, “A successful vaccine that can truly modulate the course of the COVID-19 pandemic must have four essential characteristics: safety, efficacy, scalability of manufacturing, and speed. About Cytiva.

Vaccination 52

Vaccination Vaccine Manufacturing Life Science 52

XTalks

MARCH 22, 2023

Check out the infographic that accompanies this article for more pharmaceutical industry data, along with statistics that demonstrate Xtalks as the go-to source for professionals in the life science industry. In addition, nearly half of all new drugs launched between 2020 and 2021 came with a price tag of $150,000 per year, or more.

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Life Science Drugs FDA Approval Vaccination 97

XTalks

FEBRUARY 11, 2021

After several such Nobel Prize snubs for female scientists, 2020 saw the Nobel Prize in Chemistry go to a female scientist duo for the first time for their revolutionary discovery of the CRISPR-Cas9 gene editing system. Chase was born in Cleveland, Ohio in 1927 and received a bachelor’s degree from the College of Wooster in 1950.

Genetics 119

Genetics DNA Genome Genomics 119

The Pharma Data

MAY 5, 2021

Affinia Therapeutics raises $110 million for gene therapy treatments ( STAT ). AbbVie’s Humira regains top pharma TV spender spot, while sibling brands Rinvoq and Skyrizi tag along ( Fierce ). Operating Rooms Go Under the Knife ( NYT ). Medtech. Medtech.

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Vaccination Vaccine Gene Therapy Contract Packaging 52

Pharmaceutical Technology

NOVEMBER 30, 2022

However, there has recently been a boom in interest and research in anti-obesity therapeutics. Anti-obesity therapeutic landscape. The company’s weight loss drug Saxenda (liraglutide) won an approval for chronic weight management in December 2014, and Wegovy (semaglude) got the same tag in 2021. compared to a 5.1% Free Report.

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Pharmaceutical Technology

NOVEMBER 30, 2022

However, there has recently been a boom in interest and research in anti-obesity therapeutics. Anti-obesity therapeutic landscape. The company’s weight loss drug Saxenda (liraglutide) won an approval for chronic weight management in December 2014, and Wegovy (semaglude) got the same tag in 2021. compared to a 5.1% Free Report.

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Drugs Manufacturing Hormones Contract Manufacturing 246

Pharma Marketing Network

JUNE 8, 2020

There’s another market that the majority of people operate in that is enabled by PPO networks and there’s this fiction of medical trend that gets put out there and so prices go up even though the underlying costs have gone up. And I would say well, I don’t know, we’ll go look.”

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