Medical Xpress

MAY 5, 2023

When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines. It was unclear, however, what exactly was causing this reaction.

Vaccination 119

Vaccination Vaccine 119

Pharmaceutical Technology

APRIL 28, 2023

THN391 binds the inflammation-driving component of fibrin, known for activating the immune responses in neurodegenerative and ophthalmologic diseases. The National Institute on Aging, part of the National Institutes of Health, awarded a $3m non-dilutive funding grant to Therini Bio in 2021.

Development 130

Development Immune Response Clinical Trials Clinical Trials 130

Drug Discovery World

APRIL 8, 2024

Their research signals a transformative leap in liver disease management, addressing both inflammation and fibrosis. Metabolic dysfunction-associated steatotic liver disease (MASLD) is a burgeoning global health concern, posing a significant threat to public health and escalating the burden on healthcare resources.

Drugs 52

Drugs Bioavailability Clinical Trials Clinical Trials 52

STAT News

JANUARY 17, 2023

But patients with endocarditis, an inflammation of the heart lining caused by infection, require complex, thoughtful care — care that the U.S. health system is ill-equipped to provide. The increased case count is one of the lesser-known side effects of the deadly addiction epidemic. Read the rest…

Drugs 132

Drugs 132

Medical Xpress

DECEMBER 20, 2022

Researchers using experimental animal models of IBD found that continual exposure to Allura Red AC harms gut health and promotes inflammation. Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

Research 105

Research 105

Medical Xpress

APRIL 6, 2023

New research suggests a strategy to ward off age-related weight gain, which could prevent obesity and associated health disorders like type 2 diabetes, heart disease and chronic inflammation.

Research 75

Research Gerontology 75

Pharmaceutical Technology

JANUARY 30, 2023

Sanofi Global Development, Immunology and Inflammation head Naimish Patel said: “The impact of EoE on a patient’s daily life cannot be overstated – the narrowing and scarring of the oesophagus can make something as simple as eating a painful and distressing experience and may lead to choking and food impaction.

Medicine 162

Medicine Antibody Trials Marketing 162

Medical Xpress

DECEMBER 12, 2022

The incidence rate of infective endocarditis—a rare but often fatal inflammation of the heart valves—among patients with cocaine use disorder or opioid use disorder increased from 2011 to 2022, with the steepest increase occurring from 2021 to 2022, a new study reports.

Drugs 105

Drugs Cardiology 105

Medical Xpress

MARCH 8, 2023

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody. Their results are published in the Proceedings of the National Academy of Sciences.

Antibody 75

Antibody Gene Expression Gene Trials 75

Scienmag

JANUARY 7, 2021

Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns Credit: HUMANOID Center of Research Excellence Touted by makers as a “healthy” alternative to traditional nicotine cigarettes, new research indicates the chemicals found in e-cigarettes (..)

Research 98

Research Genetics Medicine 98

BioSpace

AUGUST 2, 2021

The FDA initiated the partial hold after Novartis’ subsidiary AveXis, the developer of the therapy, told health authorities it found dorsal root ganglia mononuclear cell inflammation associated with the treatment in preclinical animal studies.

Gene Therapy 98

Gene Therapy Gene Trials Development 98

Pharmaceutical Technology

JULY 5, 2022

Sanofi has unveiled the global health brand, Impact, to make available standard of care treatments for non-profit supply to at-risk populations in low-income countries. The introduction of the Impact brand is one of the steps adopted since the formation of Sanofi Global Health last year.

Branding 147

Branding Medicine Insulin Antibody 147

Scienmag

MARCH 8, 2021

UMass Amherst study points to health benefits from reducing cigarette smoking Credit: UMass Amherst Inflammation in the body has been linked to the intensity of tobacco smoking among people with HIV, according to a team of University of Massachusetts Amherst researchers.

Research 97

Research Development Medicine 97

Pharmaceutical Technology

APRIL 17, 2023

The project aims to combat antimicrobial resistance (AMR), identified as one of the top 10 global health challenges by the World Health Organisation (WHO). Akthelia Pharmaceuticals and the University of Iceland have received a €6m European Union (EU) Horizon Grant for the IN-ARMOR project.

Drug Delivery Systems 147

Drug Delivery Systems Drug Delivery Bacteria Drugs 147

Scienmag

JANUARY 3, 2022

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood. Some bacteria cause inflammation, leading to periodontitis and other systemic diseases, such as cardiovascular disease and diabetes.

Bacteria 87

Bacteria Scientist Research 87

Scienmag

NOVEMBER 13, 2021

Intermittent fasting may not only be a hot dieting trend, but it also has broader health benefits, including helping to fight inflammation, according to a new study from researchers at the Intermountain Healthcare Heart Institute in Salt Lake City.

Research 88

Research Medicine 88

Medical Xpress

JANUARY 25, 2023

There are many forms of autoimmune disease, but by definition they all have one thing in common—they arise when the body's immunological defenses go awry and attack our cells or trigger biochemical changes that lead to inflammation and other responses that can be detrimental to our health.

Genetics 75

Genetics 75

Scienmag

MARCH 21, 2021

Study will follow patients to determine if inflammation causes long-term health effects WASHINGTON–Some patients with moderate to severe COVID-19 disease seem to experience inflammation of the thyroid gland that is different from thyroid inflammation caused by other viruses, according to a study presented virtually at ENDO 2021, the Endocrine (..)

Allergies 59

Allergies Medicine 59

Pharmaceutical Technology

MAY 19, 2023

On the same day as the FDA approval, UK’s National Institute for Health and Care Excellence (NICE) issued positive final Draft Guidance (FDG) recommending Rinvoq for Crohn’s in the same target population. AbbVie anticipates Rinvoq sales to exceed $7.5bn in 2025 and for the peak revenues from both drugs to exceed Humira’s peak sales by 2027.

FDA Approval 264

FDA Approval Dermatology Sales Clinical Trials 264

Medical Xpress

JANUARY 26, 2023

Knee osteoarthritis (OA) also known as degenerative joint disease of the knee is typically the result of progressive loss of cartilage and low grade inflammation. This common condition impacts approximately 500 million adults worldwide and is a leading cause of pain and disability.

Development 72

Development Research 72

Pharmaceutical Technology

JULY 6, 2022

Scientists at the National Institutes of Health (NIH) unit National Institute of Neurological Disorders and Stroke (NINDS) have found that Covid-19-induced immune response could damage the blood vessels of the brain and may lead to short and long-term neurological symptoms. .

Immune Response 162

Immune Response Antibody Gene DNA 162

Pharmaceutical Technology

MAY 19, 2023

Multiple sclerosis (MS) is a primary autoimmune disease in which inflammation is a core contributor to the degeneration of the central nervous system (CNS), leading to neurological disability and affecting sensory, visual, motor, and autonomic systems.

Marketing 246

Marketing Development Drugs 246

Drug Discovery World

JULY 12, 2023

Healing can be inefficient due to inflammation caused by an overreaction of the body’s immune system, which normally protects against infections. However, drugs that reduce inflammation by suppressing the whole immune response also inhibit the immune cells which promote repair.

Immune Response 52

Immune Response Drugs Scientist Regulation 52

Pharmaceutical Technology

FEBRUARY 19, 2023

LYT-200 is under clinical development by Puretech Health and currently in Phase II for Metastatic Pancreatic Cancer. The post LYT-200 by Puretech Health for Metastatic Pancreatic Cancer: Likelihood of Approval appeared first on Pharmaceutical Technology. The drug candidate acts by targeting galectin-9.

Clinical Trials 100

Clinical Trials Clinical Trials Drugs Development 100

World of DTC Marketing

OCTOBER 27, 2021

Getting patients to change their behavior for 99% of health conditions is not going to happen. Exercise has been shown to address some causes of cancer, such as obesity and inflammation but does this mean people will listen?

Production 216

Production Clinical Trials Clinical Trials Development 216

pharmaphorum

NOVEMBER 10, 2021

Germany’s vaccination advisory committee has recommended that people aged under 30 should only be offered Pfizer/BioNTech’s COVID-19 vaccine Comirnaty, saying it seems less likely to cause heart inflammation than Moderna’s rival shot Spikevax.

Vaccination 103

Vaccination Vaccine Sales Production 103

Scienmag

NOVEMBER 5, 2020

Cedars-Sinai study suggests ACE2, which helps coronavirus invade cells, may be a double-edged sword Credit: Courtesy of the National Institutes of Health LOS ANGELES (Nov.

Medicine 81

Medicine 81

Trialfacts

SEPTEMBER 21, 2023

Understanding the impact of inflammation and hormonal shifts during menopause becomes key to maintaining an optimal heart. This research study aims to uncover how inflammation and cardiovascular well-being are connected throughout a woman’s life. Qualified health professionals will monitor your health as it relates to the study.

Hormones 52

Hormones Research Development 52

Scienmag

JUNE 14, 2022

Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga.

Hormones 57

Hormones Research 57

Olympian Clinical Research

SEPTEMBER 15, 2023

Dietary Insights: How Food Choices Impact Psoriasis Inflammation plays a central role in psoriasis, with the immune system mistakenly attacking healthy skin cells, leading to the rapid turnover and buildup that results in skin plaques. Diet, as a modifiable environmental factor, profoundly affects inflammation within the body.

Clinical Research 52

Clinical Research Clinical Trials Clinical Trials Protein 52

Pharmaceutical Technology

MARCH 21, 2023

Sanofi Immunology and Inflammation Global Development head Naimish Patel said: “A vast majority of people with atopic dermatitis begin to develop symptoms during their earliest, most vulnerable years, and these symptoms can often continue through the rest of their lives.

Antibody 130

Antibody Medicine Trials Development 130

Scienmag

JUNE 10, 2021

The blood sugar-lowering drug metformin prevented pulmonary inflammation, a major factor in COVID-19 severity and mortality, in studies of mice infected by the SARS-CoV-2 coronavirus Credit: UC San Diego Health Sciences Metformin is a widely prescribed blood sugar-lowering drug.

Drugs 66

Drugs Medicine 66

The Pharma Data

MAY 22, 2023

(NASDAQ: REGN) and Sanofi today presented positive Phase 3 results evaluating the investigational use of Dupixent ® (dupilumab) compared to placebo in adults currently on maximal standard-of-care inhaled therapy (triple therapy) with uncontrolled chronic obstructive pulmonary disease (COPD) and evidence of type 2 inflammation. In the U.S.

Medicine 52

Medicine Allergies Trials Clinical Trials 52

Scienmag

JANUARY 10, 2022

Living alone for several years and/or experiencing serial relationship break-ups are strongly linked to raised levels of inflammatory markers in the blood–but only in men–finds a large population study published online in the Journal of Epidemiology & Community Health.

62

62

Scienmag

MARCH 29, 2021

Credit: Photo by Cori Kogan, Washington State University Health Sciences Spokane SPOKANE, Wash.

Protein 88

Protein Scientist Research Allergies 88

Drug Discovery World

APRIL 14, 2023

Emerging data on long Covid suggests that the virus targets the mitochondrial, which are essential to normal energy generation and control of inflammation. AXA1125, which had previously shown effects on cellular energetics and inflammation, may improve energy generation and reduce the amount of inflammation in the body.

Trials 52

Trials Clinical Trials Clinical Trials Research 52

Scienmag

SEPTEMBER 15, 2021

The health benefits of ginseng are largely attributed to compounds called ginsenosides, which are present in the roots, stems, and leaves of the plant. Ginsenosides are known to prevent inflammation, diabetes, and cancer, and can also help control blood cholesterol levels and reduce […].

Scientist 52

Scientist Medicine 52