Drug Discovery World
MAY 25, 2023
DNA Script: SYNTAX DNA printing platform Using the company’s EDS technology, the SYNTAX platform can synthesise up to 96 highly accurate, ready-to-use DNA oligos with maximum lengths of up to 120nt in less than 24 hours in the laboratory. The platform works with the SYNTAX Hi-Fidelity reagent kits for synthesising longer oligos.
Roots Analysis
AUGUST 15, 2023
Biomanufacturing utilizing cell free systems is an emerging area of research that enables the synthesis of different biomolecules, such as cytotoxic proteins, fusion proteins, post translationally modified proteins, antibodies, enzymes, vaccines and other complex proteins, without the use of living cells.
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Pharmaceutical Technology
FEBRUARY 3, 2023
The established method for this process is a triple transfection using three different DNA plasmids. Better transfection reagents and efforts to automate the currently highly manual and inconsistent process could also make a difference, he adds. For example, researchers have developed a two-plasmid cotransfection system.
The Pharma Data
JULY 11, 2021
TAKHZYRO is a fully human monoclonal antibody that specifically binds and decreases plasma kallikrein activity. TAKHZYRO is produced in Chinese Hamster Ovary (CHO) cells by recombinant DNA technology. All antibody titres were low. 2.4% (2/84) of lanadelumab-treated subjects tested positive for neutralizing antibodies.
Drug Discovery World
NOVEMBER 30, 2023
The company’s goal is to accelerate functional characterisation and shortenoptimisation time in antibody discovery and t-cell workflows. coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents.
Drug Discovery World
OCTOBER 21, 2022
Accordingly, advances in flow cytometry technology – both in instrumentation and reagent offerings – are enabling researchers to decipher these questions, leading to new discoveries and diagnostic tools. . Best antibody development practices are summarised in Fig. Overview, evolution, trends .
The Pharma Data
DECEMBER 2, 2020
Results show the protocol demonstrated a 30Gb+ yield of long DNA reads raw data of an E. The FMv8 protocol introduces a needle-aspirate-based, cell-resuspension step prior to cell lysis that boosts DNA recovery. Elsewhere around the globe: RevoluGen – U.K.-based for its cGMP-compliant CHOSOURCE platform. in Mainland China.
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