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How antibiotic resistant gut bacteria cause lung infections

Drug Discovery World

An Oxford University study has provided the first evidence that antibiotic resistant bacteria can travel from the gut to the lung, increasing the risk of deadly infections. . The study was conducted on a patient that carried the bacterium Pseudomonas aeruginosa as part of their gut microbiome. Leading cause of hospital infections.

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Newly-discovered bacteria could prevent malaria

Drug Discovery World

Research published in Science shows that a naturally occurring bacterium discovered by GSK scientists – Delftia tsuruhatensis Tres Cantos 1 (TC1) – could be the basis for new anti-malarial interventions. The results suggest TC1 has potential to inhibit the development of all malaria parasites which affect humans (P. ovale and P.

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Intravacc gets NIAID contract for intranasal gonorrhoea vaccine development

Pharmaceutical Technology

from the US National Institutes of Health (NIH) unit National Institute of Allergy and Infectious Diseases (NIAID) to develop a prophylactic intranasal vaccine against Neisseria gonorrhoeae (NG). Leveraging its outer membrane vesicles (OMV) platform technology, Intravacc will develop the vaccine.

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US researchers decipher how one gut bacterium influences immunity

Drug Discovery World

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness. New doors open.

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Powerful new antibiotic isolated from microbial ‘dark matter’

Drug Discovery World

Earlier, they developed a device that enables researchers to grow ‘bacterial dark matter’, which are so-called unculturable bacteria. Ninety-nine percent of all bacteria are ‘unculturable’ and could not be grown in laboratories previously, and therefore not be mined for novel antibiotics. terrae ssp. Carolina.

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Cause of 1990s Argentina cholera epidemic uncovered

Scienmag

Work allows genomic monitoring for epidemic strains of Vibrio cholerae bacteria The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the (..)

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Vaxcyte trains its sight on a lucrative market with pneumococcal vaccine

Pharmaceutical Technology

On 24 October, American vaccine developer Vaxcyte shared positive topline data from a Phase I/II study of its multivalent conjugate pneumococcal vaccine VAX-24 , bringing the 24-valent pneumococcal jab one step closer to market. According to the UK’s National Health Service (NHS), there are over 90 strains of this bacterium.