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Intravacc gets NIAID contract for intranasal gonorrhoea vaccine development

Pharmaceutical Technology

from the US National Institutes of Health (NIH) unit National Institute of Allergy and Infectious Diseases (NIAID) to develop a prophylactic intranasal vaccine against Neisseria gonorrhoeae (NG). Leveraging its outer membrane vesicles (OMV) platform technology, Intravacc will develop the vaccine.

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Solving a mystery: How the TB bacterium develops rapid resistance to antibiotics

Scienmag

Credit: SDSU For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

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US researchers decipher how one gut bacterium influences immunity

Drug Discovery World

A team led by researchers at HMS and the Broad has just accomplished the rare feat of connecting those dots for one important gut bacterium. The work introduces new possibilities for developing drugs that piggyback on A. You can change the bacterium and apply the same set of tests,” said Clardy. New doors open.

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Human infection model drives forward TB vaccine development

Drug Discovery World

For the first time, a controlled human infection model for tuberculosis (TB) has been developed and could help with the future development of TB vaccines. Human challenge models have contributed significantly to the development of vaccines for diseases such as malaria or typhoid, especially in early phase trials.

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Researcher receives grant to develop improved Lyme disease diagnostics and therapeutics

Scienmag

Lyme disease is carried by black-legged ticks and infects people when they are bitten and transmit the bacterium Borrelia burgdorferi. Black-legged ticks are especially common in the northeastern United States, and people are exposed to the ticks usually during outdoor activities.

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Researchers develop a new technique to treat middle ear infections

Scienmag

In a new study, researchers have designed a miniaturized 3D-printed device to inactivate Pseudomonas aeruginosa, a common bacterium that causes the infection. Credit: Jungeun Won Middle ear infections, also known as otitis media, affect more than 80% of the children in the U.S.

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How two different types of immune cells help two billion people keep tuberculosis in check

Medical Xpress

Yet, as many as two billion people are infected with Mycobaterium tuberculosis, the bacterium that causes tuberculosis, and are otherwise healthy and asymptomatic. Scientists who study TB look at those individuals who can tolerate and contain the infection in hopes of developing better treatments and vaccines.