Pharmaceutical Technology

AUGUST 1, 2022

Before the Covid-19 pandemic, government-led investment and engagement in life sciences was relatively restricted worldwide, with the industry mostly funded via private investment. AMR occurs when disease-causing bacteria become resistant or immune to the antibiotics used to treat them.

Vaccination 234

Vaccination Vaccine Bacteria Life Science 234

Scienmag

FEBRUARY 5, 2021

Membrane-localized phage proteins may also help revitalize, enhance existing antibiotics A study from the Center for Phage Technology, part of Texas A&M’s College of Agriculture and Life Sciences and Texas A&M AgriLife Research, shows how the “hidden” genes in bacteriophages — types of viruses that infect and destroy (..)

Gene 74

Gene Bacteria Life Science Development 74

Drug Discovery World

NOVEMBER 16, 2023

Glox Therapeutics has raised £4.3M ($5.2M) in seed funding to develop targeted therapeutics against antibiotic-resistant Gram-negative bacteria. Bacteriocins, which are naturally produced by bacteria, possess antimicrobial properties against strains of the same or related species.

Development 52

Development Bacteria Life Science Engineer 52

Drug Discovery World

FEBRUARY 8, 2024

In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Dr O’Hara added that when thinking about the AAV particles, they need to be quantified accurately for all downstream applications.

Gene Therapy 59

Gene Therapy Gene Bioinformatics Life Science 59

Drug Discovery World

OCTOBER 3, 2023

Earlier this year, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Dr O’Hara added that when thinking about the AAV particles, they need to be quantified accurately for all downstream applications.

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

Drug Discovery World

MAY 6, 2024

Thanks to a prestigious academic legacy, Europe has long been a dominant region for life sciences. Europe is traditionally a life sciences powerhouse, with a strong tradition in pharmaceutical discovery. The oldest, still active pharmaceutical company worldwide, Merck, started life in 1668 in Darmstadt, Germany.

Drugs 59

Drugs Life Science Gene Editing Gene 59

pharmaphorum

OCTOBER 7, 2020

Charpentier – currently at the Max Planck Unit for the Science of Pathogens in Germany – and Doudna of the University of California, Berkeley (pictured left to right), are the first two women to share the prize awarded by the Royal Swedish Academy of Sciences. — The Nobel Prize (@NobelPrize) October 7, 2020.

Gene Editing 104

Gene Editing Bacteria DNA Gene 104

XTalks

NOVEMBER 28, 2023

Following passive diffusion into the organism, metronidazole is activated in the cytoplasm of susceptible anaerobic bacteria through reduction. The reduced form of metronidazole, along with free radicals, interacts with DNA, inhibiting DNA synthesis and causing DNA degradation, ultimately leading to the demise of the bacteria.

FDA Approval 103

FDA Approval Bacteria DNA Drugs 103

Drug Discovery World

MAY 5, 2023

Gut microbes alter the body’s response to immunotherapy New research in mice has identified how gut bacteria alter the body’s response to PD-1 checkpoint blockade immunotherapy, currently used for the treatment of 25 forms of cancer.

Drugs 52

Drugs Bacteria Life Science Engineer 52

Drug Discovery World

DECEMBER 14, 2023

The new hub will become a part of the already thriving life sciences sector in the Glasgow area, most of which is centred around the university, the Cancer Research UK Scotland Institute and the BioCity cluster, making Glasgow and its surrounds one of the most important regions for drug discovery and development in the UK.

Drugs 75

Drugs Life Science Research Scientist 75

Drug Discovery World

APRIL 27, 2023

The first quarter of 2023 has seen deal flow continue for UK life science and biotech companies at all stages of development, new data from the UK BioIndustry Association and Clarivate shows. million to advance its novel bacteria-based cancer treatment. million across 20 deals, with an average deal size of £13 ($16.1)

Life Science 52

Life Science Gene Therapy Bacteria RNA 52

Drug Discovery World

AUGUST 9, 2022

Provider to the life sciences industry BioIVT has acquired enzymes manufacturer Cypex in a bid to enhance its product portfolio. . This technology enables the expression of human drug-metabolizing enzymes in bacteria, without requiring large modifications to the proteins.? .

In-Vitro 52

In-Vitro Protein Production Bacteria 52

Drug Discovery World

APRIL 11, 2024

Successful projects will gain access to UKHSA facilities where they can test clinical strains of bacteria and get support from experts in the field. He has worked in life sciences and pharmaceutical B2B publishing for seven years and was previously Editor of European Pharmaceutical Manufacturer.

Bacteria 52

Bacteria Life Science Development Containment 52

XTalks

JULY 14, 2021

CDIs typically develop after the use of antibiotics, which can wipe out the gut’s healthy bacteria. Seres’ microbiome drug SER-109 aims to restore the healthy bacteria via an oral capsule that contains a protective species of gut bacteria. Difficile infection (CDI).

Bacteria 52

Bacteria Marketing Drugs Containment 52

XTalks

DECEMBER 22, 2021

If the past year is anything to go by, then 2022 will also be a year marked by continued innovations in the life sciences. Here is a look at some life science trends to expect in the coming year, including key themes and topics in the pharmaceutical, biotechnology and medical device industries to keep an eye out for in 2022.

Life Science 98

Life Science RNA Vaccination Vaccine 98

pharmaphorum

JUNE 9, 2022

Not to mention that traditional antibiotics are designed to attack a broad spectrum of bacteria within the host’s body. These include the harmful bacterial pathogens that cause an infection, but also the beneficial bacteria which are part of the human microbiome and are essential for good health. About Micreos Pharmaceuticals.

Bacteria 102

Bacteria Development In-Vitro Drugs 102

XTalks

DECEMBER 2, 2022

difficile as certain antibiotics can disrupt the balance of bacteria in the gut, allowing bacteria like C. While Rebyota is the first of its kind pharmaceutical therapy, the concept of healing the gut via fecal matter-derived bacteria is not new. The use of certain antibiotics can contribute to infection caused by C.

FDA Approval 59

FDA Approval Bacteria Clinical Trials Clinical Trials 59

pharmaphorum

DECEMBER 15, 2020

On the back of phase 1b data the Copenhagen-based biotech said it had brought in new investors Sanofi Ventures, Adjuvant Capital and Industrifonden along with existing investors Novo Holdings, REPAIR Impact, Sunstone Life Science Ventures and LF Investment.

Bacteria 52

Bacteria Vaccination Vaccine Immune Response 52

XTalks

DECEMBER 12, 2023

The drug will have a boxed warning for increased risk of “life-threatening infections caused by encapsulated bacteria.” Given this, Fabhalta will be made available through a Risk Evaluation and Mitigation Strategy (REMS) program that requires vaccinations for encapsulated bacteria.

FDA Approval 95

FDA Approval Bacteria Trials Protein 95

XTalks

AUGUST 26, 2020

Macrophages are white blood cells that specialize in the detection, phagocytosis and destruction of bacteria and other harmful organisms. In other words, when fighting bacteria, the macrophages are programmed to be pro-inflammatory. However, when they are programmed to be anti-inflammatory, they can help decrease inflammation.

Bacteria 105

Bacteria Immune Response Protein Medicine 105

XTalks

JANUARY 22, 2021

It identifies bacteria using both genotypic and phenotypic assessments within 1.5 Empirical treatment usually gives two to three antibiotics at the same time to suppress unknown bacteria.”. fAST: Automated Bacteria Identification and Multiple Antibiotics Combination Test.

Bacteria 52

Bacteria In-Vitro Genotype Marketing 52

XTalks

APRIL 22, 2021

They specifically found that consuming excess sugar early on in life leads to an increase in levels of Parabacteroides bacteria. Related: Research Shows How Gut Bacteria Can Help Fight Cancer. The researchers found that the cognitive impairments were associated with changes in the gut microbiota induced by high sugar levels.

Development 76

Development Bacteria Research Regulation 76

XTalks

NOVEMBER 25, 2022

There are several strains of bacteria that have developed resistance to different types of antibiotics — these include MRSA (methicillin-resistant Staphylococcus aureus ) Clostridium difficile ( C. diff ) and the bacteria that cause multi-drug-resistant tuberculosis. According to the WHO, the silent pandemic leads to at least 1.3

Bacteria 98

Bacteria Life Science Development Production 98

Drug Discovery World

OCTOBER 18, 2022

The threat of antimicrobial resistance (AMR) has long been a talking point for those invested in healthcare and life sciences. The overuse, or misuse, of antimicrobials can lead to bacteria, viruses, fungi or parasites, becoming more resistant to treatments over time, making them less effective at treating infections.

Doctors 52

Doctors Doctor Bacteria Life Science 52

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). .

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

XTalks

JULY 28, 2021

Merck has scored US Food and Drug Administration (FDA) approval for its next-generation pneumonia vaccine Vaxneuvance that covers 15 different strains of the pneumococcal bacteria that causes the infection. Both next-gen shots offer enhanced protection against bacteria that can cause pneumonia, blood infections and meningitis.

FDA Approval 89

FDA Approval Vaccination Vaccine Immune Response 89

Drug Discovery World

SEPTEMBER 28, 2023

This is likely in part because their byproduct, lactic acid, is known to inhibit pathogenic bacteria 25. And, in the endometrium, a decrease in Lactobacillus may affect embryo attachment and promote the growth of detrimental bacteria. The influence of these microbiomes extends to children as well.

Clinical Trials 64

Clinical Trials Clinical Trials Regulation Bacteria 64

XTalks

JUNE 14, 2022

FL OZ (9 mL) nasal spray bottles to be contaminated with the bacteria, Providencia rettgeri. California-based Green Pharmaceuticals Inc. is recalling the 2372/21222 lot of their SnoreStop NasoSpray bottles. The US Food and Drug Administration (FDA) found the 0.3

Contamination 52

Contamination Bacterium Bacteria Branding 52

XTalks

AUGUST 2, 2022

The autoantibodies do not fight actual infection or bacteria, but rather the normal tissue in the body. In those affected by lupus, autoreactive B cells (those that react against the body), remain in the body long after the “threat” to the immune system is gone. When this behaviour is prolonged, it results in inflammation.

FDA Approval 94

FDA Approval Antibody Bacteria Protein 94

XTalks

JANUARY 6, 2021

Owing to their size, they can be grown in bacteria as opposed to larger animal or human cells, making them easier and cheaper to produce. These regions play a crucial role in the detection of antigens on viruses, bacteria and other pathogens. Several groups have been researching nanobodies as treatment options for COVID-19.

Antibody 105

Antibody Protein Bacteria In-Vitro 105

XTalks

AUGUST 9, 2023

By focusing on the removal of excess bacteria, biofilm and bacterial toxins — the chief culprits behind eyelid symptoms — BlephEx presents a potent solution for those looking for symptom relief. Beyond this cleanser, the FDA has endorsed an in-office procedure named BlephEx.

FDA Approval 98

FDA Approval In-Vitro Trials Bacteria 98

XTalks

JULY 25, 2023

The bacteria usually enter the body through wounds, but infection can also occur through contaminated meat or inhalation of spores. Anthrax is a rare, yet severe disease caused by the bacterium B. anthracis , primarily affecting livestock and wild game.

FDA Approval 98

FDA Approval Vaccination Vaccine Antibody 98

Drug Discovery World

FEBRUARY 6, 2024

The company has created a novel AI platform to develop enzymes from bacteria-killing viruses (bacteriophages) as a new way to tackle bacterial infections, and has secured €4 million investment to support its development. Obulytix is not alone.

Marketing 69

Marketing Medicine Genome Genomics 69

XTalks

AUGUST 28, 2020

Egorov told Xtalks that, “many studies being carried out right now show that one of the major ways that people get infected with COVID or any other virus or bacteria is not by sharing the bacteria [directly] by sneezing or coughing, but by [touching surfaces], holding hands and then rubbing the nose and eyes.

Containment 111

Containment Bacteria Marketing Production 111

XTalks

MAY 31, 2022

Tapinarof was discovered as an outcome of investigations into the secondary metabolites of Photorhabdus luminescens, a bioluminescent, Gram-negative bacteria. There is 10 mg of tapinarof per gram of Vtama cream. XTALKS WEBINAR: All Means All: The Road to Inclusivity in Clinical Trials.

FDA Approval 98

FDA Approval Clinical Trials Clinical Trials Trials 98

XTalks

NOVEMBER 3, 2023

The CRISPR-Cas9 gene editing system was first discovered to be endogenous in bacteria. Vertex and CRISPR Therapeutics are also seeking approval for exa-cel in beta thalassemia, the decision for which is set for March 30, 2024. CRISPR works as genetic scissors to edit parts of the genome.

Gene Therapy 59

Gene Therapy Gene Gene Editing In-Vivo 59

Drug Discovery World

OCTOBER 13, 2022

The DDW team spent 4-5 October, 2022 at ELRIG’s annual meeting, Drug Discovery 2022, which remains Europe’s largest meeting for life sciences industry professionals and took place at ExCel, London, UK.

Drugs 52

Drugs In-Vivo In-Vitro Biobanking 52