Drug Discovery World

APRIL 4, 2024

Join DDW for this free event, ‘ Higher throughput bioanalytical methods accelerate the development and evaluation of advanced biotherapeutics ’, which is supported by Revvity. Successful development of advanced biotherapeutics relies on extensive characterization and tight quality control.

Bioassay 52

Bioassay Antibody Drug Delivery Scientist 52

Pharmaceutical Technology

FEBRUARY 15, 2023

The swift development and deployment of messenger-RNA (mRNA) vaccines against the SARS-CoV-2 virus during the COVID-19 crisis has catapulted the pharmaceuticals industry into a new paradigm. Another area where we tend to see problems is in encapsulation efficiency,” says Andrew Kondratowicz, Bioassay Team Lead, Precision NanoSystems.

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Bioassay Development RNA Drugs 130

pharmaphorum

AUGUST 5, 2021

The issue, however, is developing an effective way of targeting them. . Understanding the mechanism of PPIs and developing methods to target aberrant ones has been a key strategy in drug development. In comparison with the classic, small molecule drug discovery approach, the modulation of PPIs is more challenging.

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Protein Gene Bioassay DNA 126

Drug Discovery World

AUGUST 1, 2023

Using multiple bioassays to gain insights on the effects of the CATCH regimen on different types of immune cells, the researchers showed that their strategy not only reactivated the cycle but also removed obstacles at other stages. The post RNA-based immunotherapy eradicates melanoma tumours appeared first on Drug Discovery World (DDW).

RNA 52

RNA Bioassay Genome Genomics 52

Drug Discovery World

MARCH 8, 2023

Common industry challenges that emerged at the first meeting of the Council include the automation of data analysis, enabling the Lab of the Future, and the development of industry standards to enable collaboration.

Life Science 52

Life Science Bioassay Scientist Research 52

Drug Discovery World

FEBRUARY 23, 2023

Kristen Hopson , Vice President of Preclinical Discovery and Development at Generate Biomedicines, and Yup Liu , Associate Director, HTS at Generate Biomedicines, reflect on the impact of AI, ML cloud computing, and advances in laboratory automation and high-throughput screening (HTS) on life science research.

Protein 52

Protein Life Science Bioassay Development 52

Drug Discovery World

AUGUST 12, 2022

By selecting the correct salt form for an assay or as a reagent, scientists can optimise their research projects, says Andrievs Auseklis Auzin, Developer, Molport, Latvia. As an example, one salt analysis algorithm developed by aggregator MolPort proceeds stepwise: a. The research chemical supply market. In a text field only.

Drugs 52

Drugs Bioassay Development Research 52

Drug Discovery World

MAY 4, 2023

Professor Sonika Bhatnagar explores how artificial intelligence is enabling drug discovery at rates never seen before. Here started the story of drug discovery. The magic bullet was the drug, while the specific mark it would reach in the syphilis causing bacteria to eliminate the disease was the drug target.

Medicine 52

Medicine Protein Drugs Bioassay 52

Drug Discovery World

JANUARY 19, 2023

Cell engineering is bringing life science into a new era of biotherapeutic discovery and development, disease modelling, and synthetic biology research. Furthermore, evidence of monoclonality must be provided for all cell lines producing biotherapeutic molecules if they are to receive approval from industry regulators.

Engineer 52

Engineer Bioassay Life Science Genome 52

Drug Discovery World

NOVEMBER 9, 2023

The first three include: Sungjin Park, PhD, CEO, Onegene Biotechnology, on: ‘UniStac: Enzyme-mediated conjugation technology for accelerated development of tetraspecific NASH drug’. Gail Calvert, Field Application Scientist, Sartorius UK, on: ‘Leveraging integrated and advanced technologies for successful cell line development’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

Drug Discovery World

NOVEMBER 30, 2023

Lightcast is developing a novel, programmable microfluidic platform that allows precise and highly flexible control of individual microdroplets using software-generated light patterns. “It GSK has developed high-throughput mammalian and E.

Antibody 59

Antibody Protein Engineer In-Vivo 59

Drug Discovery World

MAY 10, 2023

Dr Megan MacBride and Dr Caroline Horizny Mitchell , Taconic, examine recent changes to animal testing in drug design. Drug discovery and development is an arduous process that can cost upwards of $2.6 In August 2022, the ICH issued an addendum to its S1B guidelines that allows certain drugs to forego two-year rat studies 1.

Bioassay 52

Bioassay Genotoxicity Drugs In-Vivo 52

The Pharma Data

MAY 13, 2021

Fructose as a key player in the development of fatty liver disease. Nat Rev Drug Discov. How does brain insulin resistance develop in Alzheimer’s disease? The obesity epidemic and food addiction: clinical similarities to drug dependence. J Psychoactive Drugs. Curr Drug Abuse Rev. The Journal of Nutrition.

Insulin 52

Insulin Production Hormones Medicine 52

Pharmaceutical Technology

JANUARY 6, 2023

The preparation of a semi-solid dosage form – from formulation and development, to scale-up, commercial manufacturing, and packaging – should ideally take place under one roof in a contiguous, end-to-end workflow to avoid unnecessary equipment and process changes. Optimising development and scale-up. Particle distribution. Grittiness.

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Production Manufacturing Development Bioequivalency 130