Drug Discovery World

SEPTEMBER 20, 2022

The results were presented at the ME Genetics Research Summit organised by ME charity, Action for ME and the MRC Human Genetics Unit, University of Edinburgh. . The study also identified similarities with genes that are believed to be associated with multiple sclerosis (MS) and long Covid. Copyright: PrecisionLife.

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The Pharma Data

APRIL 11, 2023

Bayer is progressing novel research around its prostate cancer treatment darolutamide. Both small molecule inhibitors in Immuno-Oncology are being jointly developed in a strategic research alliance with the German Cancer Research Center (DKFZ) in Heidelberg, Germany.

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pharmaphorum

JULY 28, 2022

Alnylam Pharma has made a name for itself, developing gene-silencing therapies for rare disorders, but its latest discovery could take it into a much larger category – metabolic and cardiovascular disease. Transgenic mice in which the gene has been deleted have improved control of blood glucose and insulin sensitivity.

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Delveinsight

MARCH 2, 2021

Chinook will have access to the NURTuRE cohort study along with other proprietary patient biobanks and Evotec’s multi-omics integration platform, and the company plans to potentially deliver targeted therapies in rare kidney diseases such as IgA nephropathy and glomerular diseases.

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The Pharma Data

JULY 12, 2021

online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval. HUMANOID Center of Research Excellence?(CoRE),

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Drug Discovery World

OCTOBER 13, 2022

The DDW team looks forward to the remaining events on the ELRIG schedule for 2022, which include Protein Sciences in Drug Discovery 2022 at the Babraham Research Campus in Cambridge (UK), Robotics and Automation 2022 at Festo in Esslingen, Stuttgart (Germany), as well as CRISPR in Drug Discovery 2023 at the Kings Centre in Oxford (UK).

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The Pharma Data

JULY 15, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. (Nasdaq: BIIB) and Pfizer (NYSE: PFE). These genetic data have been paired with detailed health information to create this browsable resource.

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Drug Discovery World

JANUARY 24, 2024

DDW’s Megan Thomas caught up with Wigerinck to learn more about his work with small molecules for fibrosis research. MT: Your appointment comes as Fibrocor seeks to advance two drug candidates – exquisitely specific kinase inhibitor small molecules (FIB992 and FIB991) for rare indications into the clinic.

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Research Gene Expression Drugs Development 59

The Pharma Data

JULY 8, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. (Nasdaq: BIIB) and Pfizer (NYSE: PFE). These genetic data have been paired with detailed health information to create this browsable resource.

Genetics 52

Genetics Biobanking Protein Containment 52

XTalks

APRIL 15, 2021

In their 2013 paper published in the journal Hypertension , an international team of researchers describe how they performed a GWAS study using data from over 22,000 individuals with coronary artery disease and over 64,000 controls. Figure 2: Using drug-target MR to validate sympathetic nervous system genes involved in heart failure.

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The Pharma Data

JANUARY 21, 2021

Researchers at Washington University School of Medicine in St. The research was published in the journal JCI Insight. The research team evaluated 97 patients with COVID-19 at Barnes-Jewish Hospital. Specifically, the Malta patients did not have mutations in the C9orf72, SOD1, TARDBP and FUS genes.

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Drug Discovery World

OCTOBER 30, 2023

We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. SG: Chronic diseases, like endometriosis, are polygenic, caused by a complex interplay of multiple genes and other factors.

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Roots Analysis

SEPTEMBER 18, 2023

Even though, appropriately preserved biologics have immense potential for use in basic research and other medical applications, damage sustained by the membrane during freezing and thawing results in osmotic shock, which can ultimately lead to cell death.

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The Pharma Data

JANUARY 20, 2021

The UK biobank released a further dataset on COVID-19 positive patients consisting of ~4,000 confirmed COVID-19 infected patients in November 2020. The laboratory reagents are being independently cross validated at the Australian Genome Research facility (AGRF). MELBOURNE, Australia, Jan.

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