Drug Discovery World

OCTOBER 26, 2022

A study by the Qatar Genome Research Consortium, led by Dr Lotfi Chouchane from Weill Cornell Medicine-Qatar, has reported the first landscape of cancer germline mutations – hereditary mutations – in the Qatari population. . We would like to extend this bench-to-bedside approach to other familial genetic disorders .

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Genome Genomics Biobanking Genetics 52

Scienmag

JUNE 8, 2021

New research published in the Journal of Bone and Mineral Research has linked heavier birth weight with lower bone mineral density and a higher risk of bone fracture later in life.

Biobanking 44

Biobanking Genetics Research Medicine 44

pharmaphorum

JANUARY 26, 2023

Both long- and short-read sequencing today is faster, more affordable, and highly accurate, providing researchers with deep insights to fuel research. Genomic insights will increasingly be used to reduce the hundreds of millions of pounds wasted administering drugs that are ineffective due to an individual’s genetic makeup.

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Genome Genomics Genome Project Genetics 128

pharmaphorum

DECEMBER 2, 2021

GlaxoSmithKline has formed a five-year partnership with Oxford University to set up a new institute that will apply machine learning and functional genomics to the discovery of new medicines. Genetics, proteomics and digital pathology will be harnessed in order to understand the patterns of disease which vary amongst individuals, said GSK.

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The Pharma Data

JANUARY 14, 2021

from the Yale School of Medicine in New Haven, Connecticut, and colleagues conducted a one-sample Mendelian randomization (MR) study using data for participants of European descent from the U.K. Biobank that enrolled more than 500,000 Britons aged 40 to 69 years from 2006 to 2010. Acosta, M.D., percent had an SAH.

Genetics 52

Genetics Biobanking Medicine Research 52

Drug Discovery World

APRIL 4, 2024

The data are expected to drive a new level of understanding about the genetics of cardiovascular disease, mental, reproductive and female health, cancer and rare diseases, and treatment outcomes. To date, the samples for the Biobank have been genotyped using microarray-based methods.

Biobanking 52

Biobanking Genome Genomics Genome Project 52

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Generation of strong research dataset cohorts must begin with high-quality clinical samples. Biobanks are used for the coordination of high-yield patient sample collection.

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Research Biobanking Drugs Genome 98

The Pharma Data

JULY 12, 2021

online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval. HUMANOID Center of Research Excellence?(CoRE),

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Drugs Gene Expression Big Data Gene 52

The Pharma Data

JULY 15, 2021

The access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. Nasdaq: BIIB) and Pfizer (NYSE: PFE).

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Biobanking Genetics Protein Medicine 52

The Pharma Data

JULY 8, 2021

Today, access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. Nasdaq: BIIB) and Pfizer (NYSE: PFE). The browser can be accessed via [link]. About AbbVie.

Genetics 52

Genetics Biobanking Protein Containment 52

Drug Discovery World

MARCH 20, 2024

has made a landmark shift by recognising the limitations of animal models and empowering researchers to adopt non-animal methods to demonstrate drug safety and efficacy. Their adaptability for genetic modifications further positions them as an optimal tool for exploring the mechanisms of action of toxic compounds.

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Research Clinical Trials Clinical Trials In-Vivo 59

Drug Discovery World

OCTOBER 30, 2023

We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. RA: How will this data improve the chances of finding novel precision medicines for endometriosis?

Genome 72

Genome Genomics Genotype Clinical Trials 72

The Pharma Data

JANUARY 21, 2021

Researchers at Washington University School of Medicine in St. The research was published in the journal JCI Insight. The research team evaluated 97 patients with COVID-19 at Barnes-Jewish Hospital. They are now working to identify what genetic aberrations are causing ALS in about half of the Maltese patients.

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Research DNA Hormones Vaccination 52

Roots Analysis

SEPTEMBER 18, 2023

Even though, appropriately preserved biologics have immense potential for use in basic research and other medical applications, damage sustained by the membrane during freezing and thawing results in osmotic shock, which can ultimately lead to cell death.

Engineer 52

Engineer Containment In-Vivo Production 52