Medical Xpress

MARCH 9, 2023

Researchers have analyzed image and genomic data from the UK Biobank to find insights into rare diseases of the human eye. These include retinal dystrophies—a group of inherited disorders affecting the retina—which are also the leading cause of blindness certification in working-age adults.

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Scienmag

JUNE 8, 2021

New research published in the Journal of Bone and Mineral Research has linked heavier birth weight with lower bone mineral density and a higher risk of bone fracture later in life.

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Drug Discovery World

NOVEMBER 7, 2022

One might argue that this all started getting exciting with the launch of the Human Genome Project, which the National Human Genome Research Institute consider to be one of the greatest scientific feats in history 1. With Revio, researchers will be able to access that same great chemistry, but at a much larger scale.” . The origins

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Drug Discovery World

MARCH 7, 2023

Within this, Qatar is emerging as a country which is actively seeking to bolster its drug discovery and development sectors, through high levels of spending and investment into local research programmes. Qatar is a small country but faces many of the same healthcare problems that Western countries currently face.

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Drug Discovery World

DECEMBER 15, 2022

The Covid-19 Host Genetics Initiative carried out one of the largest genome-wide association studies ever. In the first article, Dr Hamdi Mbarek, Lead Analyst of the Qatari dataset, explains how the initiative improved knowledge of host-genetic determinants of Covid-19 infection and severity.

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XTalks

SEPTEMBER 16, 2022

Researchers at the Francis Crick Institute and University College London in the UK have found how air pollution can trigger the activation of cells with existing genetic mutations to form cancer. The researchers propose that particulate matter 2.5 The new research shows that air pollutants can be that ‘second hit.’

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pharmaphorum

JANUARY 26, 2023

Both long- and short-read sequencing today is faster, more affordable, and highly accurate, providing researchers with deep insights to fuel research. Genomic insights will increasingly be used to reduce the hundreds of millions of pounds wasted administering drugs that are ineffective due to an individual’s genetic makeup.

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Drug Discovery World

OCTOBER 26, 2022

A study by the Qatar Genome Research Consortium, led by Dr Lotfi Chouchane from Weill Cornell Medicine-Qatar, has reported the first landscape of cancer germline mutations – hereditary mutations – in the Qatari population. . We would like to extend this bench-to-bedside approach to other familial genetic disorders .

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Cloudbyz

NOVEMBER 3, 2021

We need human tissues and cells for biomedical research. Biosamples and biomarkers are the core basis for much of the work done in the clinical research industry and proficient Human Biosample Management (HBSM) is necessary to procure reliable biosamples. Automated Biobanking. Sample Backup.

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Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

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pharmaphorum

DECEMBER 2, 2021

Genetics, proteomics and digital pathology will be harnessed in order to understand the patterns of disease which vary amongst individuals, said GSK. ” The new institute will also draw on GSK’s partnerships with organisations, such as 23andMe and UK Biobank, that are a source of genetic information in diseases.

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Drug Discovery World

JANUARY 29, 2024

Convened by Lifebit, the event aimed to forge connections and establish partnerships with the common goal of expediting the secure utilisation of health and biomedical data in research to save lives.

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The Pharma Data

JANUARY 14, 2021

Biobank that enrolled more than 500,000 Britons aged 40 to 69 years from 2006 to 2010. A polygenic risk score was built using independent genetic variants known to associate with smoking behavior; this score represents genetic susceptibility to smoking initiation. Acosta, M.D., percent had an SAH. percent had an SAH.

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Drug Discovery World

APRIL 4, 2024

The data are expected to drive a new level of understanding about the genetics of cardiovascular disease, mental, reproductive and female health, cancer and rare diseases, and treatment outcomes. To date, the samples for the Biobank have been genotyped using microarray-based methods.

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XTalks

FEBRUARY 4, 2021

Generation of strong research dataset cohorts must begin with high-quality clinical samples. Biobanks are used for the coordination of high-yield patient sample collection. The webinar highlighted the importance of maximizing utility and sustainability for the long-term success of biorepositories and biobanks.

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Drug Discovery World

SEPTEMBER 20, 2022

Breakthroughs in gene therapy are only possible with an exact understanding of the genetic underpinnings of disease. To develop safe and effective gene therapies, researchers need confidence that genomic data is both complete and accurate. For years now the UK has been somewhat of a leader in genomic research.

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pharmaphorum

JULY 28, 2022

The RNA interference specialist says its researchers and collaborators have identified mutations in a gene called INHBE that are associated with protection against abdominal obesity and metabolic syndrome – a condition impacting more than 20% of adults worldwide. . Image by Bruno /Germany from Pixabay .

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The Pharma Data

JULY 8, 2021

Today, access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. Nasdaq: BIIB) and Pfizer (NYSE: PFE).

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The Pharma Data

JULY 15, 2021

The access to the world’s largest browsable resource linking rare protein-coding genetic variants to human health and disease was launched through a genetic exome sequence analysis collaboration between AbbVie (NYSE: ABBV), Biogen Inc. Nasdaq: BIIB) and Pfizer (NYSE: PFE).

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The Pharma Data

JULY 12, 2021

online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval. HUMANOID Center of Research Excellence?(CoRE),

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Drug Discovery World

MARCH 20, 2024

has made a landmark shift by recognising the limitations of animal models and empowering researchers to adopt non-animal methods to demonstrate drug safety and efficacy. Their adaptability for genetic modifications further positions them as an optimal tool for exploring the mechanisms of action of toxic compounds.

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The Pharma Data

NOVEMBER 4, 2020

Nasdaq: CNTG), a commercial-stage company focused on rare diseases that transforms real-world clinical and genetic data into actionable information for patients, physicians, and pharmaceutical companies, announced today the opening of its walk-in COVID-19 testing facility at the newly opened Berlin Brandenburg Airport (BER). About CENTOGENE.

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pharmaphorum

JUNE 13, 2022

An analysis of images of the retina harvested from the UK Biobank resource suggests that it may be possible to identify individuals at risk of coronary artery disease by examining the pattern of blood vessels in the retina during an eye test. ” Image by Paul Diaconu from Pixabay . .

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The Pharma Data

JANUARY 20, 2021

The UK biobank released a further dataset on COVID-19 positive patients consisting of ~4,000 confirmed COVID-19 infected patients in November 2020. The laboratory reagents are being independently cross validated at the Australian Genome Research facility (AGRF). MELBOURNE, Australia, Jan. Quarterly Results Release Date and Webinar.

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Drug Discovery World

OCTOBER 30, 2023

We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. SG: Making patients’ data accessible for responsible commercial research is key to driving innovation from initial concept to clinic implementation.

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XTalks

APRIL 15, 2021

A 2015 study published in Nature Genetics found that the availability of human genetic data made investigational drugs twice as likely to pass pivotal trials and eventually be approved. Figure 1: The use of Mendelian randomization to validate genetic drug targets.

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The Pharma Data

JANUARY 21, 2021

Researchers at Washington University School of Medicine in St. The research was published in the journal JCI Insight. The research team evaluated 97 patients with COVID-19 at Barnes-Jewish Hospital. They are now working to identify what genetic aberrations are causing ALS in about half of the Maltese patients.

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Roots Analysis

SEPTEMBER 18, 2023

Even though, appropriately preserved biologics have immense potential for use in basic research and other medical applications, damage sustained by the membrane during freezing and thawing results in osmotic shock, which can ultimately lead to cell death.

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