pharmaphorum

JANUARY 18, 2023

The idea of ‘genetic superheroes’ and precision medicine is captivating for researchers, but the concept can be abstract and distant for participants. In our experience of running 20+ precision medicine studies, there are a few design principles that every research programme – from biobanks to clinical trials – should consider.

Genetic Disease 86

Genetic Disease Genetics Research Genome 86

Drug Discovery World

MARCH 7, 2023

Within this, Qatar is emerging as a country which is actively seeking to bolster its drug discovery and development sectors, through high levels of spending and investment into local research programmes. Qatar is a small country but faces many of the same healthcare problems that Western countries currently face.

Biobanking 52

Biobanking Drugs Genome Genomics 52

Scienmag

DECEMBER 15, 2020

An Academy of Finland Academy Programme, Health from Cohorts and Biobanks (COHORT), has become a global forerunner in the collaborative use of existing research data. Over the past two decades, Finnish research on health promotion has reached a very high level in global terms.

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Biobanking Research Medicine 58

The Pharma Data

MARCH 1, 2022

to build a scalable data, analytics, and infrastructure platform This collaboration aims at capturing translational disease insights from large external healthcare biobanks and maximizing value of data for drug discovery and precision medicine. Boehringer Ingelheim partners with Lifebit Biotech, Ltd.

Biobanking 52

Biobanking Genome Genomics Genome Project 52

Drug Discovery World

NOVEMBER 7, 2022

Genomic healthcare data is critical to identify disease risk, ancestry, traits and response to medicines and aids in the development of new targeted therapies – precision medicines. With Revio, researchers will be able to access that same great chemistry, but at a much larger scale.” . The origins .

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Genome Genomics Development Genetics 98

Drug Discovery World

OCTOBER 26, 2022

A study by the Qatar Genome Research Consortium, led by Dr Lotfi Chouchane from Weill Cornell Medicine-Qatar, has reported the first landscape of cancer germline mutations – hereditary mutations – in the Qatari population. . These variants increase the risk of developing breast cancer in women and prostate cancer in men. .

Genome 52

Genome Genomics Biobanking Genetics 52

Scienmag

JUNE 8, 2021

New research published in the Journal of Bone and Mineral Research has linked heavier birth weight with lower bone mineral density and a higher risk of bone fracture later in life.

Biobanking 44

Biobanking Genetics Research Medicine 44

pharmaphorum

DECEMBER 2, 2021

GlaxoSmithKline has formed a five-year partnership with Oxford University to set up a new institute that will apply machine learning and functional genomics to the discovery of new medicines. ” The post GSK pumps £30m into a new Oxford University partnership appeared first on.

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Biobanking Genome Genomics Genetics 75

pharmaphorum

JANUARY 24, 2023

One of the reasons is because researchers now have far more genetic data to work with than was ever previously possible. With such a drop in cost, this means that researchers can test far more often and work with far more genetic data than previously possible.

Genetics 91

Genetics Drugs Genome Project Biobanking 91

Drug Discovery World

APRIL 4, 2024

Founded in 2000, the Estonian Biobank holds more than 212,000 samples – 20% of the country’s adult population – reflecting its age, sex, and geographical distribution. To date, the samples for the Biobank have been genotyped using microarray-based methods.

Biobanking 52

Biobanking Genome Genomics Genome Project 52

pharmaphorum

MARCH 19, 2021

As data and digital technology become vital to every aspect of life sciences, the industry is increasingly looking beyond biologists, chemists, and doctors to drive its drug development – and finding that technology has a chief role to play in the future of medicine. According to an article by Stephens, Zachary D.,

Bioinformatics 58

Bioinformatics Drugs Genome Genomics 58

Delveinsight

MARCH 2, 2021

Evotec and Chinook Therapeutics have collaborated to develop and discover precision medicine therapies for patients with chronic kidney diseases (CKD). The duo plans to jointly identify, characterize and validate novel mechanisms and discover and develop precision medicines. HitGen & UPPTHERA Collaborate for Drug Delivery Research.

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Drug Delivery Research Drugs Gene Editing 40

pharmaphorum

JANUARY 26, 2023

Both long- and short-read sequencing today is faster, more affordable, and highly accurate, providing researchers with deep insights to fuel research. Moreover, research has shown that genetic testing can reduce adverse reactions to drugs by nearly one third. Just one mutation can lead to a complete change in protein formation.

Genome 123

Genome Genomics Genome Project Genetics 123

The Pharma Data

APRIL 11, 2023

Bayer is progressing novel research around its prostate cancer treatment darolutamide. Both small molecule inhibitors in Immuno-Oncology are being jointly developed in a strategic research alliance with the German Cancer Research Center (DKFZ) in Heidelberg, Germany.

Research 40

Research Clinical Trials Clinical Trials Trials 40

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Generation of strong research dataset cohorts must begin with high-quality clinical samples. Biobanks are used for the coordination of high-yield patient sample collection.

Research 98

Research Biobanking Drugs Genome 98

The Pharma Data

JANUARY 14, 2021

from the Yale School of Medicine in New Haven, Connecticut, and colleagues conducted a one-sample Mendelian randomization (MR) study using data for participants of European descent from the U.K. Biobank that enrolled more than 500,000 Britons aged 40 to 69 years from 2006 to 2010. THURSDAY, Jan. 14 in Stroke. Acosta, M.D.,

Genetics 52

Genetics Biobanking Medicine Research 52

The Pharma Data

JULY 12, 2021

online issue of Nature Communications, researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval. HUMANOID Center of Research Excellence?(CoRE),

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Drugs Gene Expression Big Data Gene 52

pharmaphorum

JULY 5, 2022

George Freeman, minister for science, research and innovation at the Department for Business, Energy and Industrial Strategy, opened proceedings by reminding us of some of the UK’s recent achievements and aspirations for the future. Faster access for patients for interventions. Data on all aspects, including stratification of patient types.

Life Science 97

Life Science Biobanking Medicine Marketing 97

Drug Discovery World

FEBRUARY 27, 2024

Reece A: What are some of the human limitations to current drug discovery research for immunotherapies? From these data, we can discover new medicines with a higher probability for success. Reece A: In pharmaceutical research there is an abundance of data, much of which is untapped. Can you tell us about this approach?

Genome 52

Genome Genomics Genotype Medicine 52

Drug Discovery World

APRIL 20, 2023

Structural MRI data from the UK Biobank cohort found reductions in global brain size, particularly reduced grey matter thickness in the orbitofrontal cortex and parahippocampal gyrus, among participants who had had Covid-19, an average of 141 days before scanning 11. Is it time for the pharmaceutical industry to join in? We believe so.

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Development Drugs Clinical Trials Clinical Trials 98

The Pharma Data

DECEMBER 9, 2020

5 and attracted participants from around the world, including radiologists, radiation oncologists, physicists in medicine, radiologic technologists, and other health care professionals. The researchers found that food and housing insecurity were both associated with a longer lapse between diagnostic breast imaging and biopsy.

Radiology 52

Radiology Biobanking Genotype Medicine 52

Crucial Data Soutions

JUNE 28, 2021

Step 2: escalating to jumping on the phone to talk live with the central lab, the bioanalytical lab, the sites, the biobank or anyone else in a quest to hunt down a specific sample. Blockchain technology provides increased security and traceability, two key components important to clinical research.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Biobanking 52

Roots Analysis

DECEMBER 8, 2021

The advancements and research in the field of cellular therapies, regenerative medicine, biobanking and drug discovery have led to the demand for biopreservation media in the pharmaceutical, biotechnology and healthcare sector. The figure below portrays the various sectors / segments where media can be employed.

Packaging 52

Packaging Packaging In-Vivo Biobanking 52

Drug Discovery World

MARCH 20, 2024

has made a landmark shift by recognising the limitations of animal models and empowering researchers to adopt non-animal methods to demonstrate drug safety and efficacy. Our capabilities offer the flexibility required for innovative toxicology research. In response to these challenges, the newly passed FDA Modernization Act 2.0

Research 59

Research Clinical Trials Clinical Trials In-Vivo 59

The Pharma Data

JULY 15, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.

Biobanking 52

Biobanking Genetics Protein Medicine 52

The Pharma Data

JANUARY 31, 2021

The need for sharing information across the medical research landscape was never starker than during the early days of the COVID-19 pandemic. According to Nature Biotechnology, “81% of researchers are constrained by the inadequate quantity and quality of biospecimens and 80% of companies find accessing materials difficult.”.

Research 52

Research Biobanking Clinical Trials Clinical Trials 52

Drug Discovery World

JANUARY 24, 2024

DDW’s Megan Thomas caught up with Wigerinck to learn more about his work with small molecules for fibrosis research. MT: Your appointment comes as Fibrocor seeks to advance two drug candidates – exquisitely specific kinase inhibitor small molecules (FIB992 and FIB991) for rare indications into the clinic.

Research 59

Research Gene Expression Drugs Development 59

The Pharma Data

JULY 8, 2021

Managed by the Broad Institute of MIT and Harvard, the browser gives access to results from analyses of whole exome sequencing data from 300,000 UK Biobank research participants. AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.

Genetics 52

Genetics Biobanking Protein Containment 52

Drug Discovery World

OCTOBER 30, 2023

We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. RA: How will this data improve the chances of finding novel precision medicines for endometriosis?

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Genome Genomics Genotype Clinical Trials 72

The Pharma Data

JANUARY 21, 2021

Researchers at Washington University School of Medicine in St. The research was published in the journal JCI Insight. The research team evaluated 97 patients with COVID-19 at Barnes-Jewish Hospital. The research was conducted in mice and humans. Every week there are numerous scientific studies published.

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Research DNA Hormones Vaccination 52

Roots Analysis

SEPTEMBER 29, 2023

Since the 1980s, there have been significant advancements in the cryopreservation techniques used for storing stem cells, particularly hematopoietic stem cells and embryonic stem cells, which are essential in various medical applications, including regenerative medicine and biobanking.

Contamination 40

Contamination Containment Biobanking Packaging 40

Roots Analysis

SEPTEMBER 18, 2023

Even though, appropriately preserved biologics have immense potential for use in basic research and other medical applications, damage sustained by the membrane during freezing and thawing results in osmotic shock, which can ultimately lead to cell death.

Engineer 52

Engineer Containment In-Vivo Production 52