Drug Discovery World

OCTOBER 16, 2023

A company within this ecosystem is STORM Therapeutics, a clinical stage biotechnology company creating novel small molecule therapies that inhibit RNA modifying enzymes (RME) for use in oncology and other diseases. It has a vibrant community of life-science companies, from global pharma to smaller start-ups.

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Drug Discovery World

JANUARY 17, 2024

With oncology accounting for a third of pharma’s product pipeline, significant challenges include fierce competition, high research and development costs over, 10-15 years for clinical development, and pressures to rapidly meet the demand for new treatments 2-4.

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XTalks

OCTOBER 26, 2023

She has 23 years of experience working with clients to move vaccine candidates through the clinical development pipeline, including regulatory submission. The Flu versus COVID-19: Virology and Vaccines SARS-CoV-2 versus Influenza Virology Viruses contain genetic material that can either be RNA or DNA.

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Drug Discovery World

FEBRUARY 28, 2023

At this stage, qPCR can be used to check for IVT efficiency, residual DNA contamination and adventitious agents such as microbes. On one of the programmes, the company collaborated with a research group at University Hospital at Padova, Italy, on preclinical studies investigating a potential therapeutic for methylmalonic acidemia 5.

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Drug Discovery World

MAY 30, 2023

From antibody-drug conjugates and RNA, to CRISPR and CAR-T therapy, DDW asked the drug discovery industry what the most important development in oncology over the last five years has been. We expect this field to grow significantly in the coming years as these and other earlier stage assets are developed.

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Roots Analysis

JANUARY 3, 2024

Electroporation, also called electropermeabilization is one such effect, which has numerous therapeutic and diagnostic applications including cardiac ablation, tumor ablation and intercellular delivery of DNA, RNA, protein and other therapeutic agents.

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Drug Discovery World

OCTOBER 17, 2023

A good example of this is recent work from the labs of Martin Guilliams and Charlotte Scott, who used spatial protein and RNA readouts to generate an unprecedented atlas of human and mouse livers and were able to characterise the hepatic macrophages induced in fatty liver diseases1.

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Gene Expression Drugs Protein Gene 52

Drug Discovery World

NOVEMBER 30, 2023

Lonza’s integrated CMC strategy and timeline was presented, as well as case studies highlighting key approaches and technologies, including: vector design & integration, cell line selection, downstream process, analytical method and formulation development. kb Influenza A hemagglutinin gene was used as a model system.

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Drug Discovery World

NOVEMBER 13, 2023

Thereafter, there will be two luncheon presentations: Joseph Rucker, PhD, Vice President, Research & Development, Integral Molecular, on: ‘A humanised chicken antibody platform that delivers diverse and developable therapeutic candidates’.

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Protein Antibody Engineer Scientist 59

XTalks

AUGUST 2, 2023

With Blackstone Life Sciences, up to €300 million (around $315 million USD) will be invested to accelerate pivotal studies and clinical development programs for formulating the subcutaneous delivery of the anti-CD38 antibody Sarclisa (isatuximab) for the treatment of multiple myeloma. Veklury generated a revenue of $3.91 billion, a 31.47

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XTalks

DECEMBER 24, 2020

Omer maintains that the solution to this challenge is something that’s already in practice by developers of the mRNA vaccines. What you do is you insist that a proper clinical development program is followed and that has been followed with trial data of tens of thousands of people,” says Dr. Omer. Single-Cell RNA Sequencing.

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XTalks

SEPTEMBER 14, 2020

The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein. Below are some free webinars you can register for that have delved into the topic: Continuing Clinical Research Innovations After COVID-19. Addressing the Rapidly Evolving Vaccine Development Landscape.

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