Scienmag

JULY 22, 2021

of Mayo Clinic Cancer Center, along with collaborators from the CARRIERS consortium, suggests that most women with breast cancer diagnosed over 65 should be offered hereditary cancer genetic testing. The study was published Thursday, July 22, in the Journal of Clinical Oncology. . — A new study by Fergus Couch, Ph.D.,

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Scienmag

MAY 26, 2021

Findings published in Science Translational Medicine Credit: Cleveland Clinic May 26, 2021, CLEVELAND: According to new findings published in Science Translational Medicine, Cleveland Clinic researchers have identified a promising drug target for treating and preventing aggressive, drug-resistant prostate cancer.

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Clinical Research Research Drugs Medicine 61

Worldwide Clinical Trials

MARCH 20, 2024

In the increasingly advancing world of medicine, personalized care is a key factor that can progress your drug development efforts. One way to ensure customized disease management is to utilize pharmacogenomics (PGx) in your clinical trial. Reduces Trial Failures Oftentimes, clinical trials may fail due to a lack of efficacy.

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Drug Discovery World

MAY 17, 2023

In the future, clinical trials are going to come down to the patient level, similar to how therapies are moving toward personalisation based on biomarkers, genetics and more. EHR data also has a key role to play in designing future clinical trials.

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pharmaphorum

SEPTEMBER 28, 2022

Martin Mendoza, PhD, director of health equity and health science policy for the All of Us Research Program at the National Institutes of Health (NIH), tells pharmaphorum about the programme and how it will accelerate research for the benefit of all patients. Gathering data.

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Drug Discovery World

AUGUST 3, 2023

In the first part of this series of articles focused on plant-based medicines, DDW’s Megan Thomas evaluates the use of medical cannabis in drug discovery. Medical cannabis is often a first-thought when regarding plant-based medicines, but there remains public scepticism, arguably due to the regulations relating to the substance.

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Worldwide Clinical Trials

NOVEMBER 27, 2023

Due to inherited genetic mutations, the red blood cells of patients with severe sickle cell disease become misshaped and jagged, leading to obstructed blood vessels, intense pain, damaged organs, and other serious complications such as stroke.

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ACRP blog

APRIL 24, 2023

Courtney Burnett’s personal story, a brief history, and endless gratitude For patients and physicians alike, clinical research provides hope that ongoing innovation will offer new options to treat and even cure challenging illnesses. points out that modern healthcare and evidence-based medicine would not exist without clinical trials.

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pharmaphorum

SEPTEMBER 16, 2022

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. Kim recognised then, he said, that better tools for medicine needed to be developed, and that they still do. It also bodes well for improving clinical trial success rates.

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Drug Discovery World

JULY 5, 2023

Global Cancer Segment Market Manager at Agilent Technologies, recently sat down with DDW Editor Reece Armstrong to tell us about the developments in the ‘golden age’ of cancer research. RA: What is the current state of the cancer research industry? RA: How is Agilent supporting cancer research? Mark Garner, PhD.,

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Olympian Clinical Research

NOVEMBER 30, 2023

Vitiligo, characterized by the loss of skin pigment and the formation of white patches, has been a subject of medical intrigue and research for decades. The exact cause of vitiligo is still under investigation, with factors like genetics , autoimmune responses, and environmental triggers all playing potential roles.

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Drug Discovery World

AUGUST 18, 2023

My chosen news stories this week all discuss pre-clinical research studies that could have a huge impact on our therapeutic approach to several hard-to-treat diseases, helping to overcome drug-resistance and make treatments more targeted in the future.

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XTalks

MAY 23, 2024

One of the more intriguing developments in cancer research in recent years is the growing understanding of clonal hematopoiesis, a phenomenon where blood cells expand from a single clone due to genetic mutations. Clonal hematopoiesis increases in prevalence with age and can precede hematologic malignancies.

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Medical Xpress

NOVEMBER 21, 2022

In a new study published in Circulation: Genomics & Precision Medicine, Mayo Clinic researchers designed and developed the first suppression-replacement KCNH2 gene therapy for correcting both long QT syndrome (LQTS) and short QT syndrome (SQTS).

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Roots Analysis

AUGUST 29, 2023

Over the years, cell and gene therapies (CGT) and other advanced therapy medicinal products (ATMPs) have managed to capture the interest of both drug developers and healthcare investors. Their popularity can be attributed to various factors, such as minimal side effects, clinical efficacy and their personalized nature.

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XTalks

MARCH 20, 2024

When it comes to leadership in clinical trials today, what qualities are necessary to navigate the evolving landscape of clinical research effectively? Xtalks recently had the opportunity to discuss Enciso’s journey in the clinical research industry and her decision to join Regeneron.

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pharmaphorum

APRIL 26, 2022

In a new whitepaper, Achieving diversity, equity and inclusion in clinical trials , an expert in patient recruitment with a track record of over 16 years Clariness provides a framework to help the clinical trial research industry develop a nuanced and targeted approach to understanding who these patients are and how to make sure they’re included.

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Medical Xpress

DECEMBER 29, 2022

A clinical research team from the University of Hong Kong (HKUMed) has used amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

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Scienmag

FEBRUARY 19, 2021

Anaylsis shows different genetic risk landscape for IBD In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

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Advarra

JANUARY 11, 2024

The applications of mRNA-based therapies in cancer research represent one of the next groundbreaking steps toward improved cancer treatments. While mRNA usage has played several roles in clinical research , oncology researchers in particular are eager to explore the possibilities of mRNA-based cancer vaccines.

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pharmaphorum

MARCH 31, 2022

UK startup Sano Genetics has raised $11 million in first-round financing to develop its go-between service, which aims to overcome one of the big challenges in clinical research by connecting patients with trial sponsors. Sano says its revenues have been doubling every six months since it was formed.

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Drug Discovery World

MAY 17, 2024

Deepika Khedekar , Associate Centralized Clinical Trial Lead at IQVIA Inc, looks at the challenges of utilising artificial intelligence (AI) in oncology clinical research. MIT research 4 tells us a hard truth: about 95% of these trials fall short, leaving behind a trail of broken hopes for cancer patients each year.

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Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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XTalks

MAY 20, 2022

Do you possess laboratory skills, an analytical mindset and a penchant for research? If you enjoy working with biological samples and are enthusiastic about healthcare, a career as a clinical scientist might be just right for you. To start applying to clinical scientist jobs today, head over to the Xtalks Job Search platform.

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XTalks

MAY 17, 2023

The Foundation for the National Institutes of Health (FNIH) announced this week that the Accelerating Medicines Partnership Bespoke Gene Therapy Consortium (AMP BGTC) has selected eight rare diseases for its clinical trial portfolio. Of the more than 10,000 rare diseases, more than 80 percent are caused by genetic defects.

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Drug Discovery World

MARCH 5, 2024

In her day-to-day role, she is responsible for the development of UCB’s epilepsy discovery strategy, working with researchers to advance understanding of epilepsies while ensuring candidates for a future clinical treatment pipeline to improve the lives of those living with the condition. SD : There are multiple types of epilepsy.

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Cloudbyz

MARCH 5, 2024

In the intricate dance of drug discovery and development, two protagonists emerge as the cornerstones of modern medicine: biologics and small molecules. Monitoring and managing immunogenicity is a complex aspect of clinical trials for biologics. Identifying and minimizing these effects is a critical part of the development process.

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Drug Discovery World

FEBRUARY 10, 2023

The research will support the clinical development of CTx001, CTx’s lead gene therapy asset for the treatment of GA, by enabling the identification of patients with complement-driven AMD for future interventional studies. The post Non-interventional geographic atrophy study launches appeared first on Drug Discovery World (DDW).

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Gene Therapy Gene Genetics Clinical Development 52

Cloudbyz

NOVEMBER 30, 2021

Although you may hear some argue that with regulations catching up, and a few COVID-19 setbacks and challenges, change isn’t happening fast enough, these 6 trends we’ve identified in clinical research will prove to you that change in the clinical trial industry shows no sign of slowing down anytime soon. Personalized Medicine.

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pharmaphorum

NOVEMBER 1, 2022

million in additional funding and renewed research collaborations. Lilly chief executive David Ricks – himself a former Purdue student – said: “As the number of people who may benefit from our innovative medicines continues to increase, we are investing to advance critical research and build a more diverse pipeline of talent in Indiana.”

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Drug Discovery World

MAY 17, 2023

In the future, clinical trials are going to come down to the patient level, similar to how therapies are moving toward personalisation based on biomarkers, genetics and more. EHR data also has a key role to play in designing future clinical trials.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Genetics 52

Roots Analysis

NOVEMBER 5, 2023

In order to address the growing cancer burden, numerous cancer research organizations are actively adopting innovative strategies and patient-centered approaches for early cancer detection and treatment of cancer. According to WHO, approximately 16.3 million cancer related deaths are likely to occur by 2040.

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Drug Discovery World

JANUARY 26, 2024

Akouos, a wholly owned subsidiary of Eli Lilly, will present the results during the Late Breaking Presidential Symposium at the 2024 Association for Research in Otolaryngology (ARO) MidWinter Meeting. ” The post Gene therapy cures genetic hearing loss appeared first on Drug Discovery World (DDW). .”

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XTalks

APRIL 13, 2022

About 80 percent of rare diseases have a genetic basis. Most rare diseases are chronic conditions, and many are clinically progressive and potentially fatal. Aspects of Pediatric Medical Research. Thus, children are regarded to be vulnerable subjects for research and should have an appropriate proxy to consent for them.

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Clinical Trials Clinical Trials Clinical Research Trials 98

Pharmaceutical Technology

JUNE 15, 2023

Once the target is identified, researchers work to develop a compound that can interact with it. Algorithms can also predict the toxicity of a compound and its potential side effects, allowing researchers to focus their efforts on the most promising candidates. With the help of AI, personalized medicine can become a reality.‌

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XTalks

FEBRUARY 21, 2024

It is therefore important to work towards increasing Black participation in clinical trials, which begins with understanding the barriers to participation and taking steps to address them. Diversity in Clinical Trials Helps Advance Medicine Diverse participation in clinical trials is crucial for several reasons.

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Clinical Trials Clinical Trials Trials Life Science 59

pharmaphorum

DECEMBER 21, 2021

In a recent webinar held by pharmaphorum, in partnership with IQVIA, a discussion was held looking at how to make academic and commercial medical research more efficient, while also looking at the opportunity of genomic data to bring benefits to patients and healthcare systems. Sub-heading: The challenges in serving patients.

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