AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2022

As drug companies have embarked on an initiative to launch affordable medicines for rare diseases in India, experts have called for using pharmacogenetics to develop treatments and whole genome sequencing to identify etiologies.

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AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 11, 2023

The drug regulator, in a drug alert issued, said that a batch of Typbar, manufactured by Bharat Biotech International Ltd in Genome Valley in Hyderabad, Telangana, failed […]

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XTalks

MAY 23, 2024

Eterovic brings much knowledge and experience to the table, having led the development of a new Oncology Diagnostic program at Eurofins Viracor that integrates the latest genomic profiling techniques. Eterovic highlights that the financial and logistical barriers to comprehensive genomic profiling are high but not impossible to overcome.

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ACRP blog

JUNE 7, 2023

If you hadn’t already noticed, the clinical research enterprise has well and truly entered the era of “big data,” artificial intelligence (AI), and machine learning. As a result, the time required to design, launch, and execute high-impact clinical trials is significantly reduced.”

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AuroBlog - Aurous Healthcare Clinical Trials blog

MARCH 15, 2023

Some of the medical advances with the technology are genomics and epigenetics, Big Data, AI and ML which are allowing molecular […] Technology adoptions like artificial intelligence and machine learning are bringing in major transformation in the way a primary physician will extend treatment protocols.

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Worldwide Clinical Trials

FEBRUARY 6, 2023

When using genetic screening to identify clinical trial volunteers, a sponsor’s obligations for further testing and disclosure of results to patients and families are unclear, especially when the results have no impact on medical management. Guidance in this area is much needed. Read the full article!

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Drug Discovery World

FEBRUARY 12, 2024

We’re already seeing biotechs making breakthroughs with AI in this area, with more than 150 small molecule drugs discovered and 15 already in clinical trials. Kishen Chahwala, PhD, Business Development Manager, Enhanc3D Genomics “AI is transforming the way we fight cancer by unlocking the secrets of large and complex datasets.

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WCG Clinical

NOVEMBER 17, 2023

This change expanded the definition of HGT research to include research using nucleic acids that are able to replicate, be transcribed, translated into protein, and/or integrate into the host genome. If implemented, these changes would broaden the definition of HGT to include new gene editing and genome-modified products.

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Drug Discovery World

MAY 17, 2024

Deepika Khedekar , Associate Centralized Clinical Trial Lead at IQVIA Inc, looks at the challenges of utilising artificial intelligence (AI) in oncology clinical research. MIT research 4 tells us a hard truth: about 95% of these trials fall short, leaving behind a trail of broken hopes for cancer patients each year.

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pharmaphorum

JANUARY 18, 2023

However, the Resilience Project’s scientists had used genomic data originally collected for other studies and, due to limitations in the original studies’ informed consent policies and a lack of infrastructure to recontact participants, none of the 13 individuals could be contacted with follow-up questions or requests.

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XTalks

JANUARY 17, 2024

Lupus, a complex autoimmune disease, has brought a substantial challenge to researchers and healthcare professionals. Understanding this condition and its various manifestations, as well as developing effective treatments, has been the focus of ongoing investigation in lupus clinical research for many years.

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Drug Discovery World

NOVEMBER 8, 2023

Deepika Khedekar , Associate Centralized Clinical Lead at IQVIA, explains how artificial intelligence could make clinical trials more accurate, accessible and standardised. Tapping into the capabilities of AI One reason AI may accelerate clinical trials is its ability to rapidly process and analyse vast amounts of data.

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Drug Discovery World

JULY 12, 2023

This paid-for advertorial by BC Platforms appeared in DDW Volume 24 – Issue 3, Summer 2023 The use of real-world data (RWD) is demonstrating significant potential to enhance rare and orphan disease clinical research and development. How can researchers gain access to rare and orphan disease patient data, including RWD?

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pharmaphorum

DECEMBER 21, 2021

In a recent webinar held by pharmaphorum, in partnership with IQVIA, a discussion was held looking at how to make academic and commercial medical research more efficient, while also looking at the opportunity of genomic data to bring benefits to patients and healthcare systems. The potential to leverage genomic data.

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pharmaphorum

FEBRUARY 10, 2022

CVS Health has said it will beef up its clinical trials operations, improving its ability to recruit patients from a broad demographic spectrum, via an agreement with digital health company Medable. Pharmaceutical industry organisation PhRMA says that most delays to trials occur in the start-up phase.

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pharmaphorum

SEPTEMBER 16, 2022

Essentially, the collaboration brought together both “the right expertise and the right technology”, opening up myriad possibilities for targeting GPCRs within the human genome. It also bodes well for improving clinical trial success rates. A notable issue with clinical trials is the homogeneity of the patient database.

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Crucial Data Soutions

AUGUST 6, 2020

In this blog post, we recap the top three tips our panelists provided throughout the presentation to confront the hurdles in today’s clinical trial landscape and achieve efficient study execution. For a number of years, the clinical trials industry relied on case report forms (CRFs) and a select few non-CRF sources (i.e.,

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XTalks

MAY 23, 2024

With over 25 years of experience, Dr. Duke’s expertise in growth and bone disorders has been instrumental in advancing clinical research and improving patient outcomes. Following positive Phase II results in 2023, the company expects to launch a registrational Phase III trial later this year.

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XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. Gleich, MD, FACS, Senior Vice President, Medical Department, and Dr. Christopher Huth, PhD, Senior Clinical Trial Manager, Clinical Trial Management. Liquid Biopsy Use in Oncology Clinical Trials.

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XTalks

APRIL 24, 2023

Melanie Blank, clinical team leader for General Medicine Branch 1 at the US Food and Drug Administration’s (FDA) Division of Clinical Evaluation and Pharmacology/Toxicology (DCEPT), the agency is seeing one or two new applications coming in every week for new gene therapies for different diseases. Reference: Chung DC, et al.

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Drug Discovery World

MAY 30, 2024

Dr Pollock is the Chief Investigator of the LEGACY03 clinical trial, a study aiming to investigate lymph nodes and vaccination responses across age groups. RA: Could you tell us about the LEGACY03 trial? This is an established test in the clinic. We can compare these readouts in different groups of people.

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pharmaphorum

APRIL 23, 2020

You can listen to our March webinar here: [link] Focus During the April instalment, our expert panel will discuss: •Assessing the pharmaceutical market impact of COVID-19 •The UK clinical trials on COVID-19: navigating uncharted waters •Genomics: research in the time of COVID-19 •Knowledge sharing: the COVID-19 experience from a US perspective •Getting (..)

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Pharmaceutical Technology

FEBRUARY 26, 2023

Finch Therapeutics’s Phase III PRISM4 trial for recurrent Clostridioides difficile infection (CDI) and MaaT Pharma’s Phase III trial in steroid-resistant acute graft-versus-host disease were both put on hold. While the French MaaT Pharma has submitted further information to the FDA, its trial remains on hold. with placebo.

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XTalks

DECEMBER 1, 2020

Fortunately, technological advances — such as those pioneered by Menarini Silicon Biosystems — have allowed researchers and healthcare practitioners to decipher these issues, drilling down to single-cell genomic levels to uncover variations that may account for reduced drug efficacy or biochemical resistance. billion in 2019.

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XTalks

NOVEMBER 19, 2021

Cardiac biomarkers can not only serve important roles in the diagnosis, management and prognosis of cardiac diseases, but they can also be significant tools in evaluating treatments in cardiovascular (CV) clinical trials. In CV clinical trials, cardiac biomarkers are most commonly included in efficacy and safety endpoints.

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Pharmaceutical Technology

OCTOBER 26, 2022

Early gene therapy methods were proposed in the 1970s, and the first approved gene therapy clinical research in the US began in 1990. New doors were opened in the 2000s with the development of genome editing, such as CRISPR-Cas9, which introduces molecular tools to change existing DNA. Collaboration and integrated manufacturing.

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The Pharma Data

JANUARY 10, 2021

Nasdaq: EDIT), a leading genome editing company, today announced the U.S. Food and Drug Administration (FDA) has cleared the initiation of the safety phase of the Company’s EDIT-301 clinical trial, and the Company can begin dosing patients. Clinical trial materials are being manufactured by Editas Medicine.

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XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Partnerships and Establishing Research Cohorts. Genomic biomarker discovery helps drive the development of innovative new personalized therapies.

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XTalks

FEBRUARY 27, 2024

Sarepta hopes to clarify Elvidys’ effectiveness in older children in a confirmatory trial. Advances in Rare Disease Clinical Research Orphan Drug Legislation Many countries have implemented orphan drug acts to incentivize the development of treatments for rare diseases. The FDA introduced its Orphan Drug Act in 1983.

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XTalks

FEBRUARY 1, 2021

Montreal, Canada-based Caprion Biosciences announced last week that the clinical research organization (CRO) will rebrand as CellCarta. The move follows the 2019 merger between Caprion and HistoGeneX , a Belgian histopathology and genomics lab.

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Drug Discovery World

OCTOBER 16, 2023

Maina Bhaman, Partner at Sofinnova Partners, says: “The UK is an attractive space for drug discovery companies and a prime environment for investment due to its talent, infrastructure, and genomics research. We also recently opened the Scientific Centre of Excellence for Genomic Insight at our Cambridge site.”

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The Pharma Data

JANUARY 10, 2021

SH ) submitted its pivotal phase III clinical trial application (IND) of national class I innovative drug Chiauranib to NMPA, for the treatment of Small Cell Lung Cancer (SCLC) as a single agent for the patients after 2nd-line systemic chemotherapy and recurrence afterwards. SHENZHEN, China , Jan.

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XTalks

MAY 20, 2022

Doctors and physicians rely on the results provided by a clinical scientist to make an accurate prognosis, diagnosis and assessment for a patient’s treatment plan. What is it Like to Work as a Clinical Scientist? A clinical scientist is often synonymous with: Clinical Research / Clinical Laboratory Scientist.

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pharmaphorum

MAY 18, 2022

At the height of the COVID-19 pandemic, these capabilities were put to the test, being used to compare hospital caseloads to research activity in real-time and enabling COVID-19 clinical trials to rapidly recruit participants across the UK. Why is data important?

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Drug Discovery World

AUGUST 10, 2022

In 1987, researchers developed the chimeric antigen receptor (CAR) as an alternative means to identify cancer cells and direct T cells to attack them. And now, with more than 600 CAR T trials recruiting or ongoing, these cells represent a majority of the cellular immunotherapies in development today. Training T cells to target tumours.

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pharmaphorum

MARCH 10, 2022

“Quality, diversity, and inclusion also really matter, not just because it’s the right thing to do, but also because it improves the research. We need to make sure we’re including the right populations and communities in trials so we know how treatments will work in different populations.”.

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pharmaphorum

NOVEMBER 9, 2020

COVID-19 has sparked a flurry of research and discoveries are being made at an unprecedented rate – but patient participation cannot and should not be left behind in the rush, say leading voices. In April, 73% of clinical trials were stopped, and, as of early October, more than 40% were still on hold. Halting progress.

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