XTalks

APRIL 24, 2023

“Rare disease clinical trials are complex due to the additional scientific, medical, operational and regulatory requirements of newly emerging advanced therapies, such as gene therapy,” says Dr. Terence Eagleton, MB BS, Senior Medical Director at the global clinical research organization (CRO) Medpace.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

pharmaphorum

MAY 19, 2022

It was, they explained, stakeholders from across the healthcare ecosystem coming together to share insights, whether from clinic, research, or genomics, that changed the course of the COVID-19 pandemic. Conflicting national laws could be another important barrier to data access and use.

Genome 52

Genome Genomics Medicine Research 52

Drug Discovery World

APRIL 14, 2023

Kathryn E Wellen, PhD – Outstanding Achievement in Basic Cancer Research Wellen is an investigator at the Penn Epigenetics Institute and Vice Chair and Professor in the Department of Cancer Biology in the Perelman School of Medicine at the University of Pennsylvania. Mak’s award lecture will be held on Sunday April 16 at 12pm ET.

Genetics 52

Genetics Research Medicine Clinical Research 52

Roots Analysis

MARCH 24, 2022

Scientific fields involved in high throughput measurement of biological molecules are referred with the suffix- omics including, transcriptomics, genomics, proteomics and metabolomics. Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. Web: [link].

Clinical Research 52

Clinical Research Development Research Drug Delivery Systems 52

Drug Discovery World

NOVEMBER 8, 2023

Harnessing AI, researchers have significantly expedited the drug discovery process, achieving what traditionally takes years in just 30 days. This method not only promises more efficient drug development but could also revolutionise clinical research and accelerate trials. AI Tool Decodes Brain Cancer’s Genome During Surgery.

Clinical Trials 72

Clinical Trials Clinical Trials Trials Drugs 72

Drug Discovery World

MAY 17, 2024

Deepika Khedekar , Associate Centralized Clinical Trial Lead at IQVIA Inc, looks at the challenges of utilising artificial intelligence (AI) in oncology clinical research. Consequently, this strategy substantially reduces the failure rate of cancer clinical trials. National Human Genome Research Institute.

Trials 52

Trials Clinical Trials Clinical Trials Protein 52

Drug Discovery World

DECEMBER 8, 2023

The need for cell and gene therapy development standardisation Presently, a total of 3,866 cell and gene therapies are in various stages of development , spanning from pre-clinical research to pre-registration phases. The data needed for analysis takes months to collect and has a high cost.

Gene Therapy 64

Gene Therapy Gene In-Vitro Development 64

The Pharma Data

DECEMBER 15, 2020

As the world’s first PPAR pan agonist that completed two confirmatory phase III clinical trials, Chiglitazar Sodium has shown significant and long-lasting hypoglycemic effects in a series of clinical studies, as well as other comprehensive effects including significant insulin sensitization and blood lipid regulation.

Insulin 40

Insulin Drugs Production Clinical Trials 40

Drug Discovery World

JULY 12, 2023

This paid-for advertorial by BC Platforms appeared in DDW Volume 24 – Issue 3, Summer 2023 The use of real-world data (RWD) is demonstrating significant potential to enhance rare and orphan disease clinical research and development. How can researchers gain access to rare and orphan disease patient data, including RWD?

Research 52

Research Genome Genomics Clinical Trials 52

XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. Detection of Genomic Alterations from cfDNA: Targeted, Non-Personalized Approaches. Detection of Genomic Alterations from cfDNA: Personalized, Targeted Assays. Non-personalized approaches can be both in-house or through a service provider.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Partnerships and Establishing Research Cohorts. Genomic biomarker discovery helps drive the development of innovative new personalized therapies.

Research 98

Research Biobanking Drugs Genome 98

The Pharma Data

MARCH 11, 2021

Retevmo was approved under the FDA’s Accelerated Approval regulations based on the LIBRETTO-001 Phase 1/2 trial’s endpoints of overall response rate (ORR) and duration of response (DoR). Session Category: Clinical Research (Excluding Trials). Session Title: Disease-Oriented Innovative Clinical Research and Trials.

Research 52

Research Clinical Trials Clinical Trials Trials 52

Drug Discovery World

AUGUST 10, 2022

For example, it is challenging to regulate transgene copy numbers in each T cell, posing safety risks. If the gene does not integrate into the genome, the cell will not become a CAR T cell. The gene could also bury itself in a silenced region of the genome, leaving the gene dormant. Detecting replication-competent viruses.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

Advarra

NOVEMBER 10, 2022

This blog highlights some of the major proposed changes and how they may impact the clinical research community. . It also proposes adding information about if results will be returned to participants, under what conditions, and whether whole genome sequencing will occur. multisite research and trials).

Regulation 52

Regulation Research Genome Genomics 52

XTalks

FEBRUARY 27, 2024

XTALKS WEBINAR: A Collaborative Approach to Advancing Access and Equity in Rare Disease Clinical Trials Live and On-Demand: Thursday, February 29, 2024 , at 11am EST (4pm GMT / UK) Register for this free webinar to join the discussion with clinical trial experts on a collaborative approach to patient-friendly trials in rare disease.

Research 59

Research Drugs Gene Therapy Clinical Trials 59

pharmaphorum

SEPTEMBER 1, 2020

.” This public-spirited industry still required greater oversight, however, and government regulations on medicines increased on both sides of the Atlantic. Thalidomide and the development of drug safety regulation and monitoring. George Merck on the cover of Time magazine. New challenges in an age of innovation.

Medicine 145

Medicine Insulin Pharmacy Drugs 145

XTalks

MARCH 25, 2021

Sydney writes about various food industry topics, including safety and regulation, grocery and foodservice, innovation and sustainability. Clinical Research : Hear about new and ongoing clinical trials for various drugs, treatments and medical devices along with the latest trial data as it becomes available.

Life Science 105

Life Science HR Clinical Trials Clinical Trials 105

The Pharma Data

JANUARY 10, 2021

It is a highly-selective Aurora B, CSF1R, VEGFR/PDGFR/c-Kit inhibitor, which exerts a comprehensive anti-tumor effect by simultaneously inhibiting tumor angiogenesis, inhibiting tumor cell mitosis and regulating tumor microenvironment. Chiauranib has shown pharmacological activity superior to that of other similar drugs in animal studies.

Clinical Trials 52

Clinical Trials Clinical Trials Drugs Trials 52

pharmaphorum

DECEMBER 15, 2022

For health innovation, digital transformation in the NHS – using digital technology to change and improve services and outcomes for patients, including primary care records, legacy items, and clinical research – is critical. After all, the clinical trial environment in the UK is deteriorating, she said.

Life Science 90

Life Science Medicine Clinical Trials Clinical Trials 90

XTalks

NOVEMBER 19, 2021

Even if a robust cardiac biomarker is identified, it can run into regulatory hurdles, which is why close relationships between sponsors and regulators is critically important in order to reduce time to qualification, making it important to work hand in hand, Dr. Januzzi says. A Functional Future State.

Clinical Trials 98

Clinical Trials Clinical Trials Trials In-Vitro 98

pharmaphorum

MARCH 16, 2021

International deep real-world evidence company Savana is on a mission to give health researchers the power to unlock the clinical value embedded within electronic health records (EHRs) using artificial intelligence (AI) and clinical Natural Language Processing (NLP) techniques. AI use in the pandemic.

Doctors 113

Doctors Doctor Life Science Clinical Research 113