Drug Discovery World

MARCH 27, 2023

Genomics is driving a revolution in drug development and, in the long run, the state of public healthcare. The first draft human genome took a decade to create, and 13 years to complete. Advances in sequencing are leading to scientific breakthroughs in preventative care, faster diagnoses, and proactive medical interventions.

Genome 52

Genome Genomics Research Scientist 52

Drug Discovery World

MARCH 2, 2023

Patient identification AI can be utilised to support patient identification of rare disease patients by analysing electronic health records, medical images and genetic data for example. AI can also help personalise treatments for patients, by analysing their genetic and other health data to identify the most effective treatments.

Development 52

Development Drugs Clinical Trials Clinical Trials 52

pharmaphorum

MAY 18, 2022

At UCB, we are trying to understand the whole spectrum of triggers causing epileptic seizures, from genetic factors, brain injury to stroke, cancer or other traumas,” Charl states. Charl believes we are witnessing the ‘decade of the brain’ with significant leaps in scientific understanding of disease pathways and genetic correlations.

Gene Therapy 92

Gene Therapy Gene Genetics Development 92

XTalks

OCTOBER 19, 2023

Regulatory and Compliance Knowledge Having knowledge of the regulatory landscape is particularly relevant in clinical diagnostics or pharmaceutical industries where the assays must meet specific regulatory standards. Additionally, advances in technologies in fields like genomics, proteomics and cell biology necessitate specialized assays.

Scientist 59

Scientist Development Research Compliance 59

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Genuity Science focuses on population genomics as a tool to derive novel biological insights through partnerships with industry-leading pharmaceutical and biotech companies.

Research 98

Research Biobanking Drugs Genome 98

Advarra

SEPTEMBER 29, 2022

If genetic testing results will be returned to the site and/or the subject, include information about the Genetic Information Nondiscrimination Act (GINA). For research regulated by the Common Rule: For research involving biospecimens , whether the research will (if known) or might include whole genome sequencing.

Regulation 52

Regulation Research Genetics Compliance 52

Advarra

NOVEMBER 29, 2022

While each ultra-rare genetic disorder may have a very small patient population, when these conditions are grouped together, they make up a significant number. The BGTC will act as a traffic light for these therapies, providing information on basic and clinical research, manufacturing, production, and regulatory requirements.

Gene Therapy 52

Gene Therapy Gene Production Clinical Trials 52

The Pharma Data

NOVEMBER 24, 2020

The Notice of Compliance was granted under priority review and marks the first Health Canada approval of a PARP inhibitor in prostate cancer. Germline genetic testing in prostate cancer – further enrichment in variant histologies? MISSISSAUGA, ON , Nov. 3 Canadian Cancer Society. 4 Markowski.

Gene 52

Gene Hormones DNA Medicine 52

Drug Discovery World

JANUARY 23, 2024

The platform was recently updated to support FDA 21 CFR Part 11 compliance and include a full Installation Qualification / Operation Qualification (IQ/OQ) package for pharmaceutical quality assurance, extending the system’s applications into drug manufacturing operations. The consortium has been awarded €3.4

Compliance 52

Compliance Production Development Packaging 52

Pharmaceutical Technology

JANUARY 13, 2023

Researchers at Cedars-Sinai Medical Center have created a unique and detailed molecular profile of endometriosis, recently published in Nature Genetics , to help improve therapeutic options for the millions of women suffering from the disease.

Genetics 147

Genetics Drugs Compliance Genome 147

Drug Discovery World

JUNE 6, 2023

We’re still seeing those at the meeting at the moment”, he said, and thinks they still hold great promise for patients the better we understand patient genetics. He said: “We saw patient transcriptomics from CRUK this week, particularly all the data coming out from the TRACERx study, looking at the evolution of lung cancer.

Protein 52

Protein DNA RNA Research 52

Pharmaceutical Technology

APRIL 27, 2023

When combined with rapid advancement in delivery technologies, mRNA has the potential to lead to breakthroughs in the development of tailored treatment approaches in a wide range of indications from cancer to rare genetic disorders while enabling rapid responses to emerging threats.

Manufacturing 130

Manufacturing RNA Contamination Vaccination 130