XTalks

APRIL 29, 2021

While ARV-based treatments work well to keep the virus suppressed and patients healthy — some for many years — resistance to one or more drugs in a treatment regimen can develop in some patients. HIV drug resistance occurs when virions develop mutations that make them less susceptible to given drugs. Proviral DNA Genotyping.

DNA 98

DNA Drugs RNA Genotype 98

XTalks

APRIL 24, 2023

To achieve this, Medpace works in multi-disciplinary teams of experts to jointly develop and execute advanced therapy protocols. For rare disease studies where there is little or no clinical trial experience, outcome assessments would have to be validated within a clinical development program.

Gene Therapy 95

Gene Therapy Gene Trials Clinical Trials 95

XTalks

SEPTEMBER 15, 2020

A vaccine developed by Swedish company Diamyd Medical has demonstrated significant treatment efficacy in a predefined genetic subgroup of individuals with type 1 diabetes in a Phase IIb clinical trial. Diamyd Medical is a clinical-stage biopharmaceutical company that develops therapies for type 1 diabetes.

Vaccination 103

Vaccination Vaccine Insulin Trials 103

XTalks

APRIL 15, 2021

Experts from Servier and Genuity Science recently spoke on a webinar about using genomics data to drive drug development in heart failure and identify new targets for novel therapeutics. The reverse could also be true whereby the development of coronary artery disease may impact heart rate. HFrEF vs. HFpEF.

Development 98

Development Drugs Genome Genomics 98

The Pharma Data

MARCH 25, 2021

In addition to multiple ongoing studies of SG in triple-negative breast cancer, it is being developed as an investigational treatment for metastatic urothelial cancer, hormone receptor-positive/HER 2-negative metastatic breast cancer, and metastatic non-small cell lung cancer, either as a monotherapy or in combination with other agents.

Genotoxicity 52

Genotoxicity Genotype Containment Protein 52

XTalks

FEBRUARY 4, 2021

Data generated through high-throughput omics approaches paired with clinical patient records can give rise to remarkably robust datasets to inform and guide disease insights and development of targeted therapeutics. Genomic biomarker discovery helps drive the development of innovative new personalized therapies. Biobanking Models.

Research 98

Research Biobanking Drugs Genome 98

Roots Analysis

SEPTEMBER 20, 2023

In fact, owing to the various therapeutic applications, the government in different nations have legalized various pharmaceutical compositions containing cannabis for medical use. Cannabis-infused products primarily contain the cannabinoids cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC).

Laboratory Information Management System 40

Laboratory Information Management System Production Contamination Containment 40

Drug Discovery World

JULY 15, 2022

The Telomere-to-Telomere (T2T) Consortium successfully sequenced about 200 million remaining base pairs to approach 100% of the human genome by using the newly developed long read sequencing (LRS) technology 3,4,5. Telomeres play an important role in normal genome function and development of human disease.

Genome 52

Genome Genomics DNA Containment 52

Drug Discovery World

MAY 2, 2023

Pooled CRISPR screens usually employ lentiviral libraries comprising gRNA-containing plasmids packaged into lentiviral particles. The lentiviruses in the library contain gRNAs that target genes generated from the complete list of genes in the genome. The delivery of gRNAs is crucial for precise DNA truncation by Cas9.

Genome 52

Genome Genomics Gene DNA 52

Roots Analysis

AUGUST 31, 2023

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. For example, people affected by phenylketonuria must avoid consuming food containing phenylalanine amino acid.

Genome 40

Genome Genomics Genetics Gene 40

The Pharma Data

APRIL 14, 2021

Accelerated Approval Granted for Locally Advanced or Metastatic Urothelial Cancer Following a Platinum-Containing Chemotherapy and a PD-1/PD-L1 Inhibitor –. – New Indication Marks Second FDA Approval for Trodelvy in 2021 –. TRODELVY contains a genotoxic component, SN-38, and targets rapidly dividing cells. FOSTER CITY, Calif.–(BUSINESS

Genotype 52

Genotype Containment FDA Approval Genotoxicity 52

XTalks

NOVEMBER 10, 2020

” A rare disease diagnosis can also influence family planning options, as well as lead to better development tools, support for patients, and improved patient outcomes. We work with our users and collaborators internationally to develop these systems. ” or “Why is my child different?”

Genome 98

Genome Genomics Medicine Genetic Disease 98

The Pharma Data

APRIL 7, 2021

Today’s approval is the culmination of a multi-year development program and validates the clinical benefit of this important treatment in metastatic TNBC,” said Merdad Parsey, MD, PhD, Chief Medical Officer, Gilead Sciences. TRODELVY contains a genotoxic component, SN-38, and targets rapidly dividing cells.

HR 52

HR Genotype FDA Approval Genotoxicity 52

The Pharma Data

SEPTEMBER 2, 2021

in the US and Canada) to develop and commercialise Lynparza; with Daiichi Sankyo Company, Limited (Daiichi Sankyo) to develop and commercialise Enhertu and Dato-DXd, and with HUTCHMED to develop and commercialise savolitinib. AstraZeneca is collaborating with MSD (Merck & Co., Lead author. Abstract title. Garassino, MC.

Trials 52

Trials Medicine Antibody Clinical Trials 52