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Evolution in Hepatitis B and C Virus: Can we expect success similar to Hepatitis C in Hepatitis B as well?

Delveinsight

The first approved treatment for hepatitis C was a series of protein-based injections called recombinant interferon-alfa (IFNa). Interferons are naturally occurring proteins in the body; recombinant IFNa is the protein-based drug that works to mobilize the body’s natural immune system to fight disease. in January 2019.

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Type 1 Diabetes Vaccine: Does Diamyd Have a Winning Formula?

XTalks

Specifically, the vaccine contains human recombinant glutamate decarboxylase 65 (GAD65) protein conjugated to aluminum hydroxide (GAD-alum). The vaccine triggers an immune response against pro-inflammatory processes resulting from autoimmune attack of the pancreas – the inflammation helps to destroy the insulin-producing ?-islet

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Treatment of Metastatic Triple-Negative Breast Cancer

The Pharma Data

SG is a first-in-class therapy targeting Trop-2, a protein frequently expressed in multiple types of epithelial tumors, such as TNBC, where high expression is associated with poor survival and relapse. SG contains a genotoxic component and can cause teratogenicity and/or embryo-fetal lethality when administered to a pregnant woman.

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The doors CRISPR libraries have and will open in phenotypic drug screening 

Drug Discovery World

These modifications lead to alterations in the function of the proteins expressed by these genes, manifesting in cellular processes dependent on those proteins. This indicates that an efficient anti-cancer therapy must inhibit the activity of the proteins expressed by these genes. CRISPR libraries: Why do we need them?

Genome 52
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Why a recent advancement is a giant leap for human genomics

Drug Discovery World

Nanopore sequencing relies on determination of the chemical composition of the nucleic acids by passing a single strand of nucleic acids through a protein nanopore 6. iv) Highly repetitive regions contain some of the highest mutation rates. Telomeres play an important role in normal genome function and development of human disease.

Genome 52
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Nutrigenomics: The Future of Personalized Nutrition

Roots Analysis

For example, people affected by phenylketonuria must avoid consuming food containing phenylalanine amino acid. It is worth highlighting that nutrigenomics can be used for the treatment of inborn errors of metabolism by manipulating diet. Similarly, people suffering from lactose intolerance must avoid milk products.

Genome 40
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Trodelvy® for the Treatment of Metastatic Urothelial Cancer

The Pharma Data

Accelerated Approval Granted for Locally Advanced or Metastatic Urothelial Cancer Following a Platinum-Containing Chemotherapy and a PD-1/PD-L1 Inhibitor –. – New Indication Marks Second FDA Approval for Trodelvy in 2021 –. TRODELVY contains a genotoxic component, SN-38, and targets rapidly dividing cells. FOSTER CITY, Calif.–(BUSINESS