Drug Discovery World

SEPTEMBER 28, 2022

Winners will be evaluated based on criteria that include research objective, genomic reagent request, and how the product would be used in the field of research. . The post Up to 8 recipients to be awarded grants for genomic research appeared first on Drug Discovery World (DDW).

Genome 52

Genome Genomics Research Life Science 52

Drug Discovery World

SEPTEMBER 14, 2023

If you perform all of your tasks manually, you may need to stop your initial run partway through, which means losing the reagents and samples with which you have already begun working. Automation can track logistics, such as adding reagents to a recurring order after a certain amount is used up.

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Reagent Life Science Scientist DNA 111

pharmaphorum

JUNE 1, 2021

The dramatic rise in online drug sales during the COVID-19 pandemic has increased the supply of counterfeit drugs, and many companies are now considering the addition of on-dose authentication for high-risk or high-value products. This had led to a corresponding rise in the supply of counterfeit drugs.

Medicine 52

Medicine DNA Pharmacy Production 52

Drug Discovery World

JUNE 28, 2023

Many automation solutions can perform several different tasks and can be paired with other equipment to automate a range of tasks, such as DNA extraction and sequencing, PCR, and Western blots. Automation can track logistics, such as adding reagents to a recurring order after a certain amount is used up.

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Reagent Life Science Scientist DNA 98

Drug Discovery World

JANUARY 19, 2023

This paid-for advertorial by Catalent appeared in DDW Volume 24 – Issue 1, Winter 2022/2023 One significant challenge in the manufacturing of cell and gene therapies is the production of high-quality plasmid DNA (pDNA). billion by 2030 (BioSpace, 11 August 2022). billion by 2030 (BioSpace, 11 August 2022).

DNA 52

DNA Manufacturing Gene Therapy Gene 52

Drug Discovery World

SEPTEMBER 29, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. The post Scaling up in vitro transcription: Key results and considerations appeared first on Drug Discovery World (DDW).

In-Vitro 52

In-Vitro Reagent DNA Drugs 52

Pharmaceutical Technology

FEBRUARY 3, 2023

As opposed to other therapies or drugs that basically help you manage a condition, gene therapy has the potential to cure a disease,” says Nicole Faust, PhD, General Manager, Cell Line Development, Cytiva. The established method for this process is a triple transfection using three different DNA plasmids.

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Genome Genomics Medicine Gene Therapy 244

Drug Discovery World

NOVEMBER 2, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. The post Scaling up in vitro transcription: Exclusive free event appeared first on Drug Discovery World (DDW).

In-Vitro 52

In-Vitro Reagent DNA Production 52

Drug Discovery World

OCTOBER 23, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. The post Webinar: Scaling up IVT in mRNA production appeared first on Drug Discovery World (DDW). In this presentation, a review of the results from scaling up the IVT reaction from μg to gram scale mRNA yield will be presented.

Production 52

Production In-Vitro Reagent DNA 52

Drug Discovery World

OCTOBER 16, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. The post Understand the key considerations for scaling up in vitro transcription appeared first on Drug Discovery World (DDW).

In-Vitro 52

In-Vitro Reagent DNA Production 52

Drug Discovery World

OCTOBER 9, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. The post Exclusive event: Scaling up in vitro transcription appeared first on Drug Discovery World (DDW).

In-Vitro 52

In-Vitro Reagent DNA Production 52

Drug Discovery World

OCTOBER 2, 2023

The effect of several variables on the IVT reaction using different size DNA templates was assessed. The post Scaling up in vitro transcription: Key results and considerations appeared first on Drug Discovery World (DDW).

In-Vitro 52

In-Vitro Reagent DNA Production 52

pharmaphorum

FEBRUARY 3, 2021

While achieving the Nobel Prize spotlight would have been enough to impress, CRISPR-Cas9 gene editing is part of a growing list of technologies granted Investigational New Drug (IND) applications with early data from clinical trials supporting its safe use in edited cells re-introduced into a patient. Improving on impressive first steps.

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Gene Editing Gene DNA Engineer 98

The Pharma Data

DECEMBER 2, 2020

Food and Drug Administration (FDA) for Onivyde (irinotecan liposome injection) for study patients with small cell lung cancer (SCLC) who progressed following a first-line platinum-based regimen. Results show the protocol demonstrated a 30Gb+ yield of long DNA reads raw data of an E. The drug is a small-molecule inhibitor of the S.

Drugs 52

Drugs Gene Editing Genome Genomics 52

Drug Discovery World

OCTOBER 21, 2022

Accordingly, advances in flow cytometry technology – both in instrumentation and reagent offerings – are enabling researchers to decipher these questions, leading to new discoveries and diagnostic tools. . Reagents produced under ISO certification provide an extra level of traceability to support internal documentation and quality assurance.

Reagent 52

Reagent Antibody Drugs Protein 52

The Pharma Data

JULY 11, 2021

TAKHZYRO is produced in Chinese Hamster Ovary (CHO) cells by recombinant DNA technology. The reagents used in the aPTT laboratory test initiate intrinsic coagulation through the activation of plasma kallikrein in the contact system. No dedicated drug-drug interaction studies have been conducted. Interactions.

Allergies 52

Allergies Antibody Recombinant DNA Technology Production 52

Drug Discovery World

MAY 16, 2023

Lending to the time-to-clinic discrepancy, we also see increasing demands on manufacturing capacity for CGT reagents.” appeared first on Drug Discovery World (DDW). Furthermore, providing the flexibility needed to ramp manufacturing up or down depending on demand cycles has become more critical.”

Gene Therapy 52

Gene Therapy Gene Manufacturing Marketing 52

Roots Analysis

FEBRUARY 13, 2023

It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. The production of such drug products requires skilled labor, stringent manufacturing protocols and specialized expertise.

Manufacturing 52

Manufacturing Drug Delivery Systems Genetic Engineering RNA 52

Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Nucleic acid-based diagnostics, which typically require PCR reagents and laboratory equipment, are crucial for identifying, treating, and preventing common infectious diseases.

DNA 98

DNA Genome Genomics RNA 98

Drug Discovery World

DECEMBER 15, 2022

These platforms all induce double strand cuts in the chromosomal DNA that can be sealed by the cell, leading to a specific gene disruption, or resulting in a new target site for inserting DNA segments. Reduce/eliminate chromosomal disruptions caused by double-strand DNA breaks. In one example, Choi et al.

Gene Editing 52

Gene Editing Gene In-Vivo Genome 52

Drug Discovery World

NOVEMBER 30, 2023

coli expression systems and is using high-throughput expression pipelines to screen constructs for optimal expression to generate protein and cellular reagents. GSK has developed high-throughput mammalian and E. To demonstrate the utility of the company’s SYNTAX system in gene assembly, the 1.7

Antibody 59

Antibody Protein Engineer In-Vivo 59

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. For more details on this emerging domain, check out the following report : SPATIAL GENOMICS MARKET.

Genome 52

Genome Genomics RNA Genome Project 52

Drug Discovery World

FEBRUARY 27, 2023

The company launched its EnVision Nexus system at the show, which is designed for demanding HTS applications and to help accelerate drug discovery efforts. As the company’s first HT system, it has been designed to overcome adoption barriers currently limiting the use of predictive human liver models within drug discovery workflows.

Drugs 52

Drugs Life Science Protein Scientist 52

Drug Discovery World

JUNE 6, 2023

So, I really look forward to the coming year and being in beautiful San Diego next year.” Meet the biotech Sygnature Discovery is an integrated drug discovery and non-clinical solutions provider, offering expertise across a range of therapeutic areas and biological target classes.

Protein 52

Protein DNA RNA Research 52

Drug Discovery World

OCTOBER 14, 2022

HTS as a tool for drug discovery has evolved rapidly since the origin of the technique in the 1990s. HTS is widely used by pharmaceutical companies to identify compounds (or ‘hits’) that show pharmacological activity, which are used as starting points to optimise medicines during the drug discovery process.

Drugs 52

Drugs In-Vitro Development Production 52

Drug Discovery World

FEBRUARY 8, 2023

This helps ensure a high concentration of loaded capsids and adequate removal of impurities, such as host cell proteins and DNA. In AAV therapeutics, empty capsids are those that are not packaged with the therapeutic DNA. A crucial part of the AAV workflow is the purification of viral vectors.

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Gene Therapy Gene Antibody Production 52

The Pharma Data

AUGUST 4, 2020

Accurate monitoring of Epstein-Barr virus DNA levels is critical, as they are associated with a range of life threatening-diseases including cancer in transplant patients. Food and Drug Administration (FDA) has authorised the cobas® EBV test. to obtain comparable results when measuring levels of EBV DNA.

DNA 52

DNA In-Vitro Medicine Reagent 52

XTalks

OCTOBER 1, 2020

Xtalks spoke with WeiQi Lin, MD, PhD, executive vice president, research & development, and principal scientist at DURECT Corporation — a company focused on developing drugs and drug delivery methods in therapeutic areas with significant unmet need — about her transition from academia to industry. Key Moments.

Scientist 52

Scientist In-Vitro Research Life Science 52

The Pharma Data

SEPTEMBER 7, 2020

Food and Drug Administration (FDA) 510k clearance for the cobas® BKV Test on the cobas® 6800 and 8800 Systems. to obtain comparable results when measuring levels of BKV DNA. Basel, 8 September 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced U.S. The cobas BKV Test has robust coverage with a limit of detection of 21.5

In-Vitro 52

In-Vitro Medicine Reagent DNA 52

The Pharma Data

OCTOBER 14, 2020

The AOP Orphan Group manufactures 80% of its drugs in Europe and has more than 20 subsidiaries and representative offices across the whole of Europe as well as in the United Arab Emirates and Israel. Food and Drug Administration granted Breakthrough Therapy designation to France-based Inventiva’s experimental NASH treatment lanifibranor.

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Clinical Trials Clinical Trials Manufacturing Trials 52