March, 2021

FDA approves first CAR-T cell therapy for multiple myeloma

Bio Pharma Dive

Approval of Bristol Myers Squibb and Bluebird bio's Abecma expands use of CAR-T treatment beyond leukemia and lymphoma

The right balance in DTC: Tv versus digital ads

World of DTC Marketing

SUMMARY: Television remains the most important medium for healthcare advertising , accounting for 54.7% of all spend in 2018, far higher than television’s 30.8% share of the advertising market as a whole.

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New research adds to evidence that POTS may be an autoimmune disorder

Scienmag

Persistent work from scientists at The University of Toledo could aid in diagnosing and treating postural orthostatic tachycardia syndrome Credit: Daniel Miller / The University of Toledo The symptoms of postural orthostatic tachycardia syndrome, or POTS, can be as varied as they are confounding.

VirTrial and uMotif Partner to Further Expand Decentralized Clinical Trial Capabilities

VirTrial

Scottsdale, AZ – (March 9, 2021) – VirTrial , the leading provider of telemedicine technology, and uMotif , the patient-centric data capture platform provider, are joining forces to combine their Decentralized Clinical Trial (DCT) technologies in one seamlessly integrated solution.

EU probes low platelet safety issue with COVID-19 shots

Pharma Phorum

EU regulators are reviewing reports of low blood platelets in patients who received any of the three approved COVID-19 vaccines from Pfizer/BioNTech, AstraZeneca and Moderna.

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Caribou Biosciences is Armoring Cells to Fight Disease Through CRISPR

BioSpace

The company’s overarching aim is to edit and equip cells with molecular tools, through CRISPR, to eliminate certain cancers

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5 FDA approval decisions to watch in the second quarter

Bio Pharma Dive

A long-awaited reckoning for Biogen’s Alzheimer’s drug and the review of AstraZeneca’s coronavirus vaccine are among the top FDA decisions expected before the end of June

More Trending

Russian biologists discover a transmissible cancer lineage in the Far Eastern mussels

Scienmag

The disease can have an adverse effect on the populations of these molluscs, which are extensively farmed in Russia. Credit: SPbU ‘A transmissible cancer was first discovered in dogs in the middle of the 19th century.

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U.S. Health Officials Question AstraZeneca Vaccine Trial Results

NY Times

According to federal officials, an independent panel of medical experts said the promising results announced by the company on Monday may have relied on “outdated information.”.

Trials 110

IBM-led group wins German contract for digital vaccine passport

Pharma Phorum

Germany has awarded a tender to a consortium led by IBM to develop a secure app that will provide a digital version of the country’s paper vaccine certificates. The €2.7 million ($3.2

New Drug Approval Could Be on Horizon for Alzheimer’s after 17-Year Drought

BioSpace

A drug to halt the progression of Alzheimer’s disease will likely be approved within the next three years, and Alzheon’s ALZ-801 might be the leading candidate

Drugs 113

A year with COVID-19: The impact of data on pharma marketing

Bio Pharma Dive

Learn how three pharma brands used data to validate and adjust their promotional spend in 2020

What’s the call to action on DTC?

World of DTC Marketing

TEASER: What DTC marketers and consumers do as the result of seeing a relevant DTC ad differs by a wide margin. DTC marketers would like to think that patients ask for the advertised drug when visiting their doctor, but that’s largely untrue.

Clearing of woody weeds in Baringo County, Kenya, may yield major livelihood benefits

Scienmag

A new study suggests that clearing the invasive woody weed Prosopis julifora and grassland restoration in Baringo County, Kenya, may have significant financial benefits for local stakeholders and contribute to climate change mitigation.

VirTrial Launches eConsent Solution as Stand-Alone Offering or Bundled With Its Telemedicine Platform

VirTrial

Scottsdale, AZ (March 2, 2021) – VirTrial today announced the general availability of SmartSignals eConsent, a PDF-based, clinical trial consent solution offering rapid implementation and a flexible, scalable, and lightweight design.

Life-sciences pros believe in potential of AI, blockchain: survey

Outsourcing Pharma

A survey by the Pistoia Alliance indicates most professionals believe the tech can accelerate R&D, but companies are stymied by a skills gap and data bias. Markets & Regulations

Ocugen to Seek EUA for India-Developed COVID-19 Vaccine in the United States

BioSpace

Pennsylvania-based Ocugen has struck a deal to sell 100 million doses of a COVID-19 vaccine India’s Bharat Biotech in the United States later this year

Roche stops giving Huntington's disease drug in closely watched study

Bio Pharma Dive

A disappointing recommendation from outside data reviewers raises doubts about the DNA-targeting drug's benefits and puts pressure on Roche's partner, Ionis Pharmaceuticals

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Should doctors refuse to treat obese patients?

World of DTC Marketing

IN BRIEF: Doctors are not required to treat obese patients who won’t do anything to lose weight but the problem is more than reminding patients they need to get exercise and drop pounds.

How our microplastic waste becomes ‘hubs’ for pathogens, antibiotic-resistant bacteria

Scienmag

Gamification for patient care, medical education, and virtual engagement

Pharma Phorum

“Gamification” – adding game-like elements into non-game or real-world settings – has become a popular concept in the pharmaceutical, healthcare, and event industries, especially as virtual engagement becomes more common during COVID-19. However, it is proving more than a mere buzzword.

One and Done: Why People Are Eager for Johnson & Johnson’s Vaccine

NY Times

Johnson & Johnson’s one-shot vaccine is allowing states to rethink distribution, even as health officials and experts worry some will view it as inferior.

After About 50 Years, the mRNA Revolution is Here

BioSpace

Between the Moderna and Pfizer-BioNTech COVID-19 vaccines, there are two mRNA therapeutics on the market … the only two

Crucial data on AstraZeneca's vaccine are coming. Here's what we may learn.

Bio Pharma Dive

Results from previous trials have raised questions about the vaccine and how well it works. Data from a large U.S. study could help clear up the confusion

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Profiteering off a Covid vaccine

World of DTC Marketing

SUMMARY: Johnson & Johnson and AstraZeneca publicly committed to not profiting off their products during the pandemic; Pfizer and Moderna made no such pledge and are already planning ways to make more money from their Covid vaccines.

Inflammation-fighting protein could improve treatment of rheumatoid arthritis

Scienmag

Credit: Photo by Cori Kogan, Washington State University Health Sciences Spokane SPOKANE, Wash.

AZ’s vaccine safety review shows ‘no evidence’ of an increased risk of blood clots

Pharma Times

Review included available safety data from over 17 million people vaccinated in the EU and UK with COVID-19 jab

AI algorithm automates analysis of cystic fibrosis scans

Outsourcing Pharma

Artificial intelligence software company Thirona has released PRAGMA-AI, technology that automates and accelerates CT scans in cystic fibrosis analysis. Clinical Development

DeepVerge’s nanochip-based COVID breath test could be ready this year

Pharma Phorum

DeepVerge has announced trial data showing its COVID-19 Microtox BT breath test can deliver accurate results in under 60 seconds, with a potential roll-out later this year if further tests support it.

Rivals J&J, Merck are latest to team up to boost production of coronavirus vaccines

Bio Pharma Dive

Merck will lend J&J the use of two separate facilities in the unusual agreement, which was brokered by the Biden administration and could help double supply of the one-dose shot

Can ROI ever be used with patient-centric?

World of DTC Marketing

SUMMARY: The goal of business is to maximize profits for shareholder returns but when a company that serves the public good pays CEOs millions of dollars in compensation while having among the highest profit margins within ANY industry I would argue that something is dreadfully wrong. The U.S.

New drug to regenerate lost teeth

Scienmag

Antibody for USAG-1 shown to stimulate tooth growth Credit: Kyoto University/Katsu Takahashi Japan — The tooth fairy is a welcome guest for any child who has lost a tooth.

Pfizer and BioNTech ramp up COVID-19 vaccine production to 2.5 billion doses

BioPharma Reporter

Pfizer and BioNTech expect to expand COVID-19 vaccine manufacturing capacity to up to 2.5 billion doses by the end of 2021, thanks to the optimization of production processes and the recent initiation of production in Marburg, Germany. Bio Developments

FDA Halts bamlanivimab Distribution in Three States as COVID-19 Variants Spread

BioSpace

The FDA will limit the use of monoclonal antibody treatments developed by Regeneron and Eli Lilly due to concerns the medications are not effective against these new strains

India's Covaxin Covid-19 Vaccine, Already in Use, Shows Promise in Trials

NY Times

Interim results from clinical trials suggested that Covaxin could be safe and effective, potentially removing one hurdle to New Delhi’s ambitious campaign to inoculate a vast population.

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FDA advisers reassert case against approval of Biogen's Alzheimer's drug

Bio Pharma Dive

In a new editorial, three of the agency's advisers reiterated that they see "no persuasive evidence to support approval of aducanumab at this time "

Drugs 233

Pharma’s reputational high will be short-lived

World of DTC Marketing

SUMMARY: Via the Financial Times , “pharmaceutical companies have never had it so good.