Gene Expression Genomics Medicine Scientist 
Drug Discovery World
NOVEMBER 1, 2022
Splicing-linked expression design. Two methods currently used to deliver protein-making packages into cells, ‘mini promoters’ and serotype-mediated gene expression, vary widely. Credit: Alexei Bygrave, Johns Hopkins Medicine. Dubbed ‘splicing-linked expression design’ (SLED). . in their effectiveness. “We
pharmaphorum
OCTOBER 19, 2022
million ($40 million) first-round financing that will be used to explore so-called ‘dark’ regions of the human genome. M Ventures’ Dr Bauke Anninga said that that the startup has a “differentiated platform technology has the potential to fundamentally shift the way we discover and develop precision medicines.
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Drug Discovery World
OCTOBER 6, 2023
In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of genetics, genomics and gene editing in drug discovery.
The Pharma Data
FEBRUARY 24, 2022
UNC researchers now show that these two factors can directly associate with one another, modulating cancer-cell-specific programs of gene expression. ” They found that EZH2 possesses two different binding patterns on chromatin in acute leukemia cells, eliciting two distinct gene-regulatory programs (Figure 1). .”
Drug Discovery World
JULY 10, 2023
If there’s one thing I would take from the Summer 2023 issue of Drug Discovery World , it would be that the application of technologies and processes throughout the pharmaceutical industry are changing how scientists pursue the development of therapies. This was done to assess the accuracy of the team’s machine-learning algorithms.
The Pharma Data
MARCH 7, 2022
Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports. “The beauty of this approach is we can safely upregulate specific genes to affect cell activity without permanently changing the genome and cause unintended mistakes,” Levy said. .
Drug Discovery World
DECEMBER 12, 2022
The announcement followed the signing of deals to make new medicines available across the country. . Other research updates include a study by NIH 5 researchers using post-mortem brain tissues to understand genomic differences in individuals with attention deficit hyperactivity disorder. Analysis .
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