Gene Expression Medicine Protein Scientist 
Drug Discovery World
NOVEMBER 1, 2022
Researchers say they have successfully used a cell’s natural process for making proteins to ‘slide’ genetic instructions into a cell and produce critical proteins missing from those cells. . Splicing-linked expression design. Credit: Alexei Bygrave, Johns Hopkins Medicine. in their effectiveness. “We
The Pharma Data
MARCH 7, 2022
By combining CRISPR technology with a protein designed with artificial intelligence (AI), it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports.
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The Pharma Data
FEBRUARY 24, 2022
UNC researchers now show that these two factors can directly associate with one another, modulating cancer-cell-specific programs of gene expression. ” They found that EZH2 possesses two different binding patterns on chromatin in acute leukemia cells, eliciting two distinct gene-regulatory programs (Figure 1). .”
Scienmag
APRIL 5, 2021
Study shows that tumor-suppressor protein p53 brings speckles and DNA together to boost gene expression PHILADELPHIA – A team led by scientists at the Perelman School of Medicine at the University of Pennsylvania has illuminated the functions of mysterious structures in cells called “nuclear speckles,” showing that they can work in (..)
Drug Discovery World
OCTOBER 6, 2023
In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of genetics, genomics and gene editing in drug discovery.
XTalks
SEPTEMBER 21, 2020
UCSF scientists found that having an additional copy of the sex chromosome gives women two “doses” of a gene found only on that chromosome. The study was published in the journal Science Translational Medicine. The gene, called KDM6A , is a histone demethylase that is believed to function as a tumor suppressor.
XTalks
FEBRUARY 11, 2021
Much of the fundamental groundwork for genetics and genomic research was laid in the 20 th century, with significant contributions from women scientists, some of whom worked during times when acceptance of female researchers was not widespread. Here is a profile of some of those brilliant women who helped shape genetics research.
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